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Aging effect on plasma metabolites and hormones concentrations in riding horses.

Kawasumi K, Yamamoto M, Koide M, Okada Y, Mori N, Yamamoto I, Arai T - Open Vet J (2015)

Bottom Line: Animals were divided into two groups: Young (3-8 years) and aged (11-18 years).Plasma non-esterified fatty acid levels and Insulin and malondialdehyde concentrations in aged group tended to increase compared to those in young group although there were not significant differences statistically.In aged group, malate dehydrogenase/lactate dehydrogenase (M/L) ratio, which is considered an energy metabolic indicator, did not change significantly compared to that in young group.

View Article: PubMed Central - PubMed

Affiliation: Department of Basic Veterinary Medicine, School of Veterinary Medicine, Nippon Veterinary and Life Science University, 1-7-1 Kyonancho, Musashino, Tokyo 180-8602, Japan.

ABSTRACT
Age effects on plasma metabolites, hormone concentrations, and enzyme activities related to energy metabolism were investigated in 20 riding horses. Animals were divided into two groups: Young (3-8 years) and aged (11-18 years). They were clinically healthy, and not obese. Plasma adiponectin (ADN) concentrations in aged horses were significantly lower than those in young horses (mean±SE, 6.5±1.3 µg mL(-1) vs, 10.9±1.7 µg mL(-1), Mann-Whitney U test, respectively; P=0.0233). Plasma non-esterified fatty acid levels and Insulin and malondialdehyde concentrations in aged group tended to increase compared to those in young group although there were not significant differences statistically. In aged group, malate dehydrogenase/lactate dehydrogenase (M/L) ratio, which is considered an energy metabolic indicator, did not change significantly compared to that in young group. Present data suggest that aging may negatively affect nutrition metabolism, but not induce remarkable changes in M/L ratio in riding horses.

No MeSH data available.


Related in: MedlinePlus

Representative horses in this study. Left: A young horse with EBCS 4 (Thoroughbred, female 7 years old). Right: An aged horse with EBCS 4 (Thoroughbred, gelding 18 years old).
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Figure 1: Representative horses in this study. Left: A young horse with EBCS 4 (Thoroughbred, female 7 years old). Right: An aged horse with EBCS 4 (Thoroughbred, gelding 18 years old).

Mentions: All profiles of horses examined in this study were shown in Table 1. Animals were judged as EBCS 4 by the modified Carroll and Huntington EBCS scoring system (Carroll and Huntington, 1988). They were healthy and not obese as shown in Fig.1. Their body weight ranges were estimated from 450 kg to 500 kg.


Aging effect on plasma metabolites and hormones concentrations in riding horses.

Kawasumi K, Yamamoto M, Koide M, Okada Y, Mori N, Yamamoto I, Arai T - Open Vet J (2015)

Representative horses in this study. Left: A young horse with EBCS 4 (Thoroughbred, female 7 years old). Right: An aged horse with EBCS 4 (Thoroughbred, gelding 18 years old).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4663796&req=5

Figure 1: Representative horses in this study. Left: A young horse with EBCS 4 (Thoroughbred, female 7 years old). Right: An aged horse with EBCS 4 (Thoroughbred, gelding 18 years old).
Mentions: All profiles of horses examined in this study were shown in Table 1. Animals were judged as EBCS 4 by the modified Carroll and Huntington EBCS scoring system (Carroll and Huntington, 1988). They were healthy and not obese as shown in Fig.1. Their body weight ranges were estimated from 450 kg to 500 kg.

Bottom Line: Animals were divided into two groups: Young (3-8 years) and aged (11-18 years).Plasma non-esterified fatty acid levels and Insulin and malondialdehyde concentrations in aged group tended to increase compared to those in young group although there were not significant differences statistically.In aged group, malate dehydrogenase/lactate dehydrogenase (M/L) ratio, which is considered an energy metabolic indicator, did not change significantly compared to that in young group.

View Article: PubMed Central - PubMed

Affiliation: Department of Basic Veterinary Medicine, School of Veterinary Medicine, Nippon Veterinary and Life Science University, 1-7-1 Kyonancho, Musashino, Tokyo 180-8602, Japan.

ABSTRACT
Age effects on plasma metabolites, hormone concentrations, and enzyme activities related to energy metabolism were investigated in 20 riding horses. Animals were divided into two groups: Young (3-8 years) and aged (11-18 years). They were clinically healthy, and not obese. Plasma adiponectin (ADN) concentrations in aged horses were significantly lower than those in young horses (mean±SE, 6.5±1.3 µg mL(-1) vs, 10.9±1.7 µg mL(-1), Mann-Whitney U test, respectively; P=0.0233). Plasma non-esterified fatty acid levels and Insulin and malondialdehyde concentrations in aged group tended to increase compared to those in young group although there were not significant differences statistically. In aged group, malate dehydrogenase/lactate dehydrogenase (M/L) ratio, which is considered an energy metabolic indicator, did not change significantly compared to that in young group. Present data suggest that aging may negatively affect nutrition metabolism, but not induce remarkable changes in M/L ratio in riding horses.

No MeSH data available.


Related in: MedlinePlus