Computed tomography neck (left lateral view) showing th

Unmasking of primary hyperparathyroidism by Vitamin D therapy. Bala S, Shah B, Rajput P, Rao P - Indian J Nephrol (2015 Nov-Dec) Bottom Line: A 38-year-old female on Vitamin D therapy presented with hypercalcemia induced acute kidney injury.Evaluation revealed primary hyperparathyroidism (PHPT) and iatrogenic hypervitaminosis D.This case highlights unmasking of subclinical hyperparathyroidism by vitamin D therapy leading to severe hypercalcemia. View Article: PubMed Central - PubMed Affiliation: Department of Nephrology, Global Hospital, Mumbai, Maharashtra, India. ABSTRACT A 38-year-old female on Vitamin D therapy presented with hypercalcemia induced acute kidney injury. Evaluation revealed primary hyperparathyroidism (PHPT) and iatrogenic hypervitaminosis D. After medical stabilization, she underwent surgical removal of the parathyroid adenoma, and made a full recovery. This case highlights unmasking of subclinical hyperparathyroidism by vitamin D therapy leading to severe hypercalcemia. No MeSH data available. Related in: MedlinePlus	© Copyright Policy - open-access Related In: Results - Collection License Show All Figures getmorefigures.php?uid=PMC4663778&req=5 Figure 2: Computed tomography neck (left lateral view) showing the left parathyroid adenoma Mentions: Physical examination was unremarkable. Investigations showed high 25(OH) Vitamin D (25(OH) D) at 100 ng/ml and elevated iPTH at 1464.90 pg/ml. Serum protein electrophoresis was normal. Electrocardiography showed short QT interval of 260 ms. USG kidneys showed normal sized kidneys. Computed tomography of the neck showed parathyroid adenoma of the left lower pole [Figures 1 and 2]. Sestamibi scan confirmed the parathyroid adenoma [Figure 3].

Unmasking of primary hyperparathyroidism by Vitamin D therapy.

Bala S, Shah B, Rajput P, Rao P - Indian J Nephrol (2015 Nov-Dec)

Bottom Line: A 38-year-old female on Vitamin D therapy presented with hypercalcemia induced acute kidney injury.Evaluation revealed primary hyperparathyroidism (PHPT) and iatrogenic hypervitaminosis D.This case highlights unmasking of subclinical hyperparathyroidism by vitamin D therapy leading to severe hypercalcemia.

View Article: PubMed Central - PubMed

Affiliation: Department of Nephrology, Global Hospital, Mumbai, Maharashtra, India.

ABSTRACT

A 38-year-old female on Vitamin D therapy presented with hypercalcemia induced acute kidney injury. Evaluation revealed primary hyperparathyroidism (PHPT) and iatrogenic hypervitaminosis D. After medical stabilization, she underwent surgical removal of the parathyroid adenoma, and made a full recovery. This case highlights unmasking of subclinical hyperparathyroidism by vitamin D therapy leading to severe hypercalcemia.

No MeSH data available.

Related in: MedlinePlus

Computed tomography neck (left lateral view) showing the left parathyroid adenoma

Related In: Results - Collection

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Figure 2: Computed tomography neck (left lateral view) showing the left parathyroid adenoma

Mentions: Physical examination was unremarkable. Investigations showed high 25(OH) Vitamin D (25(OH) D) at 100 ng/ml and elevated iPTH at 1464.90 pg/ml. Serum protein electrophoresis was normal. Electrocardiography showed short QT interval of 260 ms. USG kidneys showed normal sized kidneys. Computed tomography of the neck showed parathyroid adenoma of the left lower pole [Figures 1 and 2]. Sestamibi scan confirmed the parathyroid adenoma [Figure 3].