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Adequacy of twice weekly hemodialysis in end stage renal disease patients at a tertiary care dialysis centre.

Chauhan R, Mendonca S - Indian J Nephrol (2015 Nov-Dec)

Bottom Line: Hemoglobin (Hb) levels, albumin levels, mean arterial pressure and World Health Organization (WHO) quality of life (QoL) score were compared in the two groups after 6 months.There was significant improvement in Hb levels (1.47 vs. 0.15 g/dl), mean arterial pressure levels (15.2 vs. 3.16 mm Hg), serum albumin levels (0.82 vs. 0.11 g/dl) and WHO QoL score (17.2 vs. 2.24) in study group as compared to control group.However, studies with larger sample size are required to conclusively prove our results.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, Command Hospital (Southern Command), Wanowrie, Pune, Maharashtra, India.

ABSTRACT
Hemodialysis has improved the morbidity and mortality associated with end stage renal disease. In India, hemodialysis prescription is empiric, which leads to complications related to under-dialysis. Hence, adequacy of hemodialysis in Indian setting was analyzed in this study. A total of 50 patients on twice per week hemodialysis were assessed for 1 month. The number of sessions meeting standards laid out by Kidney Diseases Outcome Quality Initiatives (KDOQI) guidelines were calculated. They were divided into two groups: one in whom dialysis was monitored and session length enhanced to meet the minimum standard Kt/V of 2 and second control group; where Kt/V was not monitored. Hemoglobin (Hb) levels, albumin levels, mean arterial pressure and World Health Organization (WHO) quality of life (QoL) score were compared in the two groups after 6 months. Only 28% of hemodialysis sessions were adequate as per KDOQI guidelines. There was significant improvement in Hb levels (1.47 vs. 0.15 g/dl), mean arterial pressure levels (15.2 vs. 3.16 mm Hg), serum albumin levels (0.82 vs. 0.11 g/dl) and WHO QoL score (17.2 vs. 2.24) in study group as compared to control group. Standard Kt/V can be used as an important tool to modify twice weekly dialysis sessions to provide better QoL to the patients. However, studies with larger sample size are required to conclusively prove our results.

No MeSH data available.


Related in: MedlinePlus

Bar diagram depicting change in all parameters. Significant improvement in group A (dialysis sessions monitored and modified as per Kt/V) as compared to group B (continued on conventional 4 h dialysis sessions twice per week)
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Figure 3: Bar diagram depicting change in all parameters. Significant improvement in group A (dialysis sessions monitored and modified as per Kt/V) as compared to group B (continued on conventional 4 h dialysis sessions twice per week)

Mentions: The average hemodialysis duration in study group (group A) was 318.22 ± 34.11 (range: 240–360) min. In group B, the average duration was 240 ± 30 min [Figure 3].


Adequacy of twice weekly hemodialysis in end stage renal disease patients at a tertiary care dialysis centre.

Chauhan R, Mendonca S - Indian J Nephrol (2015 Nov-Dec)

Bar diagram depicting change in all parameters. Significant improvement in group A (dialysis sessions monitored and modified as per Kt/V) as compared to group B (continued on conventional 4 h dialysis sessions twice per week)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4663768&req=5

Figure 3: Bar diagram depicting change in all parameters. Significant improvement in group A (dialysis sessions monitored and modified as per Kt/V) as compared to group B (continued on conventional 4 h dialysis sessions twice per week)
Mentions: The average hemodialysis duration in study group (group A) was 318.22 ± 34.11 (range: 240–360) min. In group B, the average duration was 240 ± 30 min [Figure 3].

Bottom Line: Hemoglobin (Hb) levels, albumin levels, mean arterial pressure and World Health Organization (WHO) quality of life (QoL) score were compared in the two groups after 6 months.There was significant improvement in Hb levels (1.47 vs. 0.15 g/dl), mean arterial pressure levels (15.2 vs. 3.16 mm Hg), serum albumin levels (0.82 vs. 0.11 g/dl) and WHO QoL score (17.2 vs. 2.24) in study group as compared to control group.However, studies with larger sample size are required to conclusively prove our results.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, Command Hospital (Southern Command), Wanowrie, Pune, Maharashtra, India.

ABSTRACT
Hemodialysis has improved the morbidity and mortality associated with end stage renal disease. In India, hemodialysis prescription is empiric, which leads to complications related to under-dialysis. Hence, adequacy of hemodialysis in Indian setting was analyzed in this study. A total of 50 patients on twice per week hemodialysis were assessed for 1 month. The number of sessions meeting standards laid out by Kidney Diseases Outcome Quality Initiatives (KDOQI) guidelines were calculated. They were divided into two groups: one in whom dialysis was monitored and session length enhanced to meet the minimum standard Kt/V of 2 and second control group; where Kt/V was not monitored. Hemoglobin (Hb) levels, albumin levels, mean arterial pressure and World Health Organization (WHO) quality of life (QoL) score were compared in the two groups after 6 months. Only 28% of hemodialysis sessions were adequate as per KDOQI guidelines. There was significant improvement in Hb levels (1.47 vs. 0.15 g/dl), mean arterial pressure levels (15.2 vs. 3.16 mm Hg), serum albumin levels (0.82 vs. 0.11 g/dl) and WHO QoL score (17.2 vs. 2.24) in study group as compared to control group. Standard Kt/V can be used as an important tool to modify twice weekly dialysis sessions to provide better QoL to the patients. However, studies with larger sample size are required to conclusively prove our results.

No MeSH data available.


Related in: MedlinePlus