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Prevalence of schizophrenia in China between 1990 and 2010.

Chan KY, Zhao FF, Meng S, Demaio AR, Reed C, Theodoratou E, Campbell H, Wang W, Rudan I, Global Health Epidemiology Reference Group (GHER - J Glob Health (2015)

Bottom Line: In rural areas, the corresponding rates were 0.37% (0.34-0.40%), 0.43% (0.42-0.44%) and 0.50% (0.47-0.53%).The number of cases rose to 7.16 (6.57-7.75) million in 2010, a 132% increase, while the total population increased by 18%.The contribution of cases from urban areas to the overall burden increased from 27% in 1990 to 62% in 2010.

View Article: PubMed Central - PubMed

Affiliation: Centre for Population Health Sciences and Global Health Academy, University of Edinburgh Medical School, Scotland, UK ; World Health Organization's Collaborative Centre for Population Health Research and Training ; Nossal Institute for Global Health, University of Melbourne, Australia ; Joint first authors.

ABSTRACT

Background: Dramatic development and changes in lifestyle in many low and middle-income countries (LMIC) over the past three decades may have affected mental health of their populations. Being the largest country and having the most striking record of development, industrialization and urbanization, China provides an important opportunity for studying the nature and magnitude of possible effects.

Methods: We reviewed CNKI, WanFang and PubMed databases for epidemiological studies of schizophrenia in mainland China published between 1990 and 2010. We identified 42 studies that reported schizophrenia prevalence using internationally recognized diagnostic criteria, with breakdown by rural and urban residency. The analysis involved a total of 2 284 957 persons, with 10 506 diagnosed with schizophrenia. Bayesian methods were used to estimate the probability of case of schizophrenia ("prevalence") by type of residency in different years.

Findings: In urban China, lifetime prevalence was 0.39% (0.37-0.41%) in 1990, 0.57% (0.55-0.59%) in 2000 and 0.83% (0.75-0.91%) in 2010. In rural areas, the corresponding rates were 0.37% (0.34-0.40%), 0.43% (0.42-0.44%) and 0.50% (0.47-0.53%). In 1990 there were 3.09 (2.87-3.32) million people in China affected with schizophrenia during their lifetime. The number of cases rose to 7.16 (6.57-7.75) million in 2010, a 132% increase, while the total population increased by 18%. The contribution of cases from urban areas to the overall burden increased from 27% in 1990 to 62% in 2010.

Conclusions: The prevalence of schizophrenia in China has more than doubled between 1990 and 2010, with rates being particularly high in the most developed areas of modern China. This has broad implications, as the ongoing development in LMIC countries may be increasing the global prevalence of schizophrenia.

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Absolute number of schizophrenia cases in China 1990–2010 by type of residency, based on estimates of lifetime prevalence.
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Figure 3: Absolute number of schizophrenia cases in China 1990–2010 by type of residency, based on estimates of lifetime prevalence.

Mentions: Applying those probabilities to the corresponding population estimates for China and taking into account the percentage living in urban areas in 1990, 2000 and 2010, it is estimated that there were 3.09 (2.87–3.32) million persons in China affected with schizophrenia during their lifetime in the year 1990. 27% of the cases were from urban areas, which is comparable to the population of China rbanizatio as “urban” in 1990 in demographic records [11]. By 2010, the number of persons ever affected with schizophrenia has risen sharply to 7.16 (6.57–7.75) million – a 132% increase – while the total population of China only increased by 18% during this period [11]. Moreover, the contribution of expected cases from developed urban areas to the overall burden increased from 27% in 1990 to 62% in 2010, well above the proportion of urban residents in China in 2010 that was just below 50% (Figure 3) [11].


Prevalence of schizophrenia in China between 1990 and 2010.

Chan KY, Zhao FF, Meng S, Demaio AR, Reed C, Theodoratou E, Campbell H, Wang W, Rudan I, Global Health Epidemiology Reference Group (GHER - J Glob Health (2015)

Absolute number of schizophrenia cases in China 1990–2010 by type of residency, based on estimates of lifetime prevalence.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4663755&req=5

Figure 3: Absolute number of schizophrenia cases in China 1990–2010 by type of residency, based on estimates of lifetime prevalence.
Mentions: Applying those probabilities to the corresponding population estimates for China and taking into account the percentage living in urban areas in 1990, 2000 and 2010, it is estimated that there were 3.09 (2.87–3.32) million persons in China affected with schizophrenia during their lifetime in the year 1990. 27% of the cases were from urban areas, which is comparable to the population of China rbanizatio as “urban” in 1990 in demographic records [11]. By 2010, the number of persons ever affected with schizophrenia has risen sharply to 7.16 (6.57–7.75) million – a 132% increase – while the total population of China only increased by 18% during this period [11]. Moreover, the contribution of expected cases from developed urban areas to the overall burden increased from 27% in 1990 to 62% in 2010, well above the proportion of urban residents in China in 2010 that was just below 50% (Figure 3) [11].

Bottom Line: In rural areas, the corresponding rates were 0.37% (0.34-0.40%), 0.43% (0.42-0.44%) and 0.50% (0.47-0.53%).The number of cases rose to 7.16 (6.57-7.75) million in 2010, a 132% increase, while the total population increased by 18%.The contribution of cases from urban areas to the overall burden increased from 27% in 1990 to 62% in 2010.

View Article: PubMed Central - PubMed

Affiliation: Centre for Population Health Sciences and Global Health Academy, University of Edinburgh Medical School, Scotland, UK ; World Health Organization's Collaborative Centre for Population Health Research and Training ; Nossal Institute for Global Health, University of Melbourne, Australia ; Joint first authors.

ABSTRACT

Background: Dramatic development and changes in lifestyle in many low and middle-income countries (LMIC) over the past three decades may have affected mental health of their populations. Being the largest country and having the most striking record of development, industrialization and urbanization, China provides an important opportunity for studying the nature and magnitude of possible effects.

Methods: We reviewed CNKI, WanFang and PubMed databases for epidemiological studies of schizophrenia in mainland China published between 1990 and 2010. We identified 42 studies that reported schizophrenia prevalence using internationally recognized diagnostic criteria, with breakdown by rural and urban residency. The analysis involved a total of 2 284 957 persons, with 10 506 diagnosed with schizophrenia. Bayesian methods were used to estimate the probability of case of schizophrenia ("prevalence") by type of residency in different years.

Findings: In urban China, lifetime prevalence was 0.39% (0.37-0.41%) in 1990, 0.57% (0.55-0.59%) in 2000 and 0.83% (0.75-0.91%) in 2010. In rural areas, the corresponding rates were 0.37% (0.34-0.40%), 0.43% (0.42-0.44%) and 0.50% (0.47-0.53%). In 1990 there were 3.09 (2.87-3.32) million people in China affected with schizophrenia during their lifetime. The number of cases rose to 7.16 (6.57-7.75) million in 2010, a 132% increase, while the total population increased by 18%. The contribution of cases from urban areas to the overall burden increased from 27% in 1990 to 62% in 2010.

Conclusions: The prevalence of schizophrenia in China has more than doubled between 1990 and 2010, with rates being particularly high in the most developed areas of modern China. This has broad implications, as the ongoing development in LMIC countries may be increasing the global prevalence of schizophrenia.

Show MeSH
Related in: MedlinePlus