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Assessing potentially inappropriate prescribing (PIP) and predicting patient outcomes in Ontario's older population: a population-based cohort study applying subsets of the STOPP/START and Beers' criteria in large health administrative databases.

Bjerre LM, Ramsay T, Cahir C, Ryan C, Halil R, Farrell B, Thavorn K, Catley C, Hawken S, Gillespie U, Manuel DG - BMJ Open (2015)

Bottom Line: The aim of this study is to describe the occurrence of PIP in Ontario's older population (aged 65 years and older), and to assess the health outcomes and health system costs associated with PIP-more specifically, the association between PIP and the occurrence of ED visits, hospitalisations and death, and their related costs.Ethical approval was obtained from the Ottawa Health Services Network Ethical Review Board and from the Bruyère Research Institute Ethics Review Board.Dissemination will occur via publication, presentation at national and international conferences, and ongoing exchanges with regional, provincial and national stakeholders, including the Ontario Drug Policy Research Network and the Ontario Ministry of Health and Long-Term Care.

View Article: PubMed Central - PubMed

Affiliation: Department of Family Medicine, University of Ottawa, Ottawa, Ontario, Canada Bruyère Research Institute, Ottawa, Ontario, Canada ICES@ uOttawa, Ottawa, Ontario, Canada School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, Ontario, Canada.

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Definition of observation period (OHIP, Ontario Health Insurance Plan).
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BMJOPEN2015010146F1: Definition of observation period (OHIP, Ontario Health Insurance Plan).

Mentions: The study period will span from 1 April 2002 to 31 March 2014. These dates were chosen based on availability for all the required databases at the projected time of study initiation (fall 2015); should recent data be available at the time the study is conducted, the end of the study period will be adjusted to allow inclusion of these data. The accrual period is defined at the period for ascertainment of exposure (the occurrence of PIP); it starts 1 year after the start of the study period (ie, on 1 April 2003), and ends 1 year before the end of the study period (ie, on 31 March 2013). This will allow a 1-year look-back period preceding the first included PIP, to describe prior health services utilisation, medication use and comorbidities (baseline risks), as well as a 1-year follow-up period after the last possible PIP, to allow for adequate follow-up of patient outcomes (see figure 1 for a graphical illustration of study period, accrual period and time frame for ascertainment of baseline risks, exposures and outcomes).


Assessing potentially inappropriate prescribing (PIP) and predicting patient outcomes in Ontario's older population: a population-based cohort study applying subsets of the STOPP/START and Beers' criteria in large health administrative databases.

Bjerre LM, Ramsay T, Cahir C, Ryan C, Halil R, Farrell B, Thavorn K, Catley C, Hawken S, Gillespie U, Manuel DG - BMJ Open (2015)

Definition of observation period (OHIP, Ontario Health Insurance Plan).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4663446&req=5

BMJOPEN2015010146F1: Definition of observation period (OHIP, Ontario Health Insurance Plan).
Mentions: The study period will span from 1 April 2002 to 31 March 2014. These dates were chosen based on availability for all the required databases at the projected time of study initiation (fall 2015); should recent data be available at the time the study is conducted, the end of the study period will be adjusted to allow inclusion of these data. The accrual period is defined at the period for ascertainment of exposure (the occurrence of PIP); it starts 1 year after the start of the study period (ie, on 1 April 2003), and ends 1 year before the end of the study period (ie, on 31 March 2013). This will allow a 1-year look-back period preceding the first included PIP, to describe prior health services utilisation, medication use and comorbidities (baseline risks), as well as a 1-year follow-up period after the last possible PIP, to allow for adequate follow-up of patient outcomes (see figure 1 for a graphical illustration of study period, accrual period and time frame for ascertainment of baseline risks, exposures and outcomes).

Bottom Line: The aim of this study is to describe the occurrence of PIP in Ontario's older population (aged 65 years and older), and to assess the health outcomes and health system costs associated with PIP-more specifically, the association between PIP and the occurrence of ED visits, hospitalisations and death, and their related costs.Ethical approval was obtained from the Ottawa Health Services Network Ethical Review Board and from the Bruyère Research Institute Ethics Review Board.Dissemination will occur via publication, presentation at national and international conferences, and ongoing exchanges with regional, provincial and national stakeholders, including the Ontario Drug Policy Research Network and the Ontario Ministry of Health and Long-Term Care.

View Article: PubMed Central - PubMed

Affiliation: Department of Family Medicine, University of Ottawa, Ottawa, Ontario, Canada Bruyère Research Institute, Ottawa, Ontario, Canada ICES@ uOttawa, Ottawa, Ontario, Canada School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, Ontario, Canada.

Show MeSH
Related in: MedlinePlus