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Memory for gist and detail information in patients with Parkinson's disease.

Yu RL, Tan CH, Wu YR, Wu RM, Chiu MJ, Hua MS - BMJ Open (2015)

Bottom Line: Memory deficits have been reported in patients with Parkinson's disease (PD); however, few studies have explicitly addressed the nature of these deficits.Each participant received a gist-based recognition test following the Deese-Roediger-McDermott paradigm, as well as neuropsychological tests and measures of clinical characteristics.Correlation analysis showed that item-specific memory was related to executive functions in normal controls and early-stage patients with PD (H&Y stage: I-II); however, item-specific memory was related to episodic memory, rather than to executive functions, in advanced-stage patients with PD.

View Article: PubMed Central - PubMed

Affiliation: Institute of Behavioral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

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Related in: MedlinePlus

Gist and item-specific memory performances among the study groups (*p<0.05). The advanced-stage PD group exhibited the worst gist memory performance; no significant difference in item-specific memory performance was found between the three groups. NC, normal controls; PD, Parkinson's disease.
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BMJOPEN2015009795F1: Gist and item-specific memory performances among the study groups (*p<0.05). The advanced-stage PD group exhibited the worst gist memory performance; no significant difference in item-specific memory performance was found between the three groups. NC, normal controls; PD, Parkinson's disease.

Mentions: As shown in table 2 and figure 1, after correcting for response bias, the ANOVA revealed a significant group difference in gist memory (F2,64=3.58, p=0.033). Post hoc tests indicated that the advanced-stage PD group had the worst gist memory performance. No significant difference in item-specific memory was found between the three groups. Furthermore, there was a significant group effect (F2,64=6.00, p=0.004) for the corrected target recognition rate (studied–unstudied). At the individual level, there was a significant intra-subject difference in the performance of item-specific memory relative to that of gist memory in the DRM paradigm among early-stage patients with PD (paired t test, t(28)=4.13, p<0.0001) and NCs (t(27)=4.23, p<0.0001).


Memory for gist and detail information in patients with Parkinson's disease.

Yu RL, Tan CH, Wu YR, Wu RM, Chiu MJ, Hua MS - BMJ Open (2015)

Gist and item-specific memory performances among the study groups (*p<0.05). The advanced-stage PD group exhibited the worst gist memory performance; no significant difference in item-specific memory performance was found between the three groups. NC, normal controls; PD, Parkinson's disease.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4663425&req=5

BMJOPEN2015009795F1: Gist and item-specific memory performances among the study groups (*p<0.05). The advanced-stage PD group exhibited the worst gist memory performance; no significant difference in item-specific memory performance was found between the three groups. NC, normal controls; PD, Parkinson's disease.
Mentions: As shown in table 2 and figure 1, after correcting for response bias, the ANOVA revealed a significant group difference in gist memory (F2,64=3.58, p=0.033). Post hoc tests indicated that the advanced-stage PD group had the worst gist memory performance. No significant difference in item-specific memory was found between the three groups. Furthermore, there was a significant group effect (F2,64=6.00, p=0.004) for the corrected target recognition rate (studied–unstudied). At the individual level, there was a significant intra-subject difference in the performance of item-specific memory relative to that of gist memory in the DRM paradigm among early-stage patients with PD (paired t test, t(28)=4.13, p<0.0001) and NCs (t(27)=4.23, p<0.0001).

Bottom Line: Memory deficits have been reported in patients with Parkinson's disease (PD); however, few studies have explicitly addressed the nature of these deficits.Each participant received a gist-based recognition test following the Deese-Roediger-McDermott paradigm, as well as neuropsychological tests and measures of clinical characteristics.Correlation analysis showed that item-specific memory was related to executive functions in normal controls and early-stage patients with PD (H&Y stage: I-II); however, item-specific memory was related to episodic memory, rather than to executive functions, in advanced-stage patients with PD.

View Article: PubMed Central - PubMed

Affiliation: Institute of Behavioral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

Show MeSH
Related in: MedlinePlus