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Use of high doses of folic acid supplements in pregnant women in Spain: an INMA cohort study.

Navarrete-Muñoz EM, Valera-Gran D, García de la Hera M, Gimenez-Monzo D, Morales E, Julvez J, Riaño I, Tardón A, Ibarluzea J, Santa-Marina L, Murcia M, Rebagliato M, Vioque J, INMA Proje - BMJ Open (2015)

Bottom Line: In the second period, only tobacco smoking was significantly associated with high FAS dosage use (RRR=0.67).A high proportion of pregnant women did not reach the recommended dosages of FAS in periconception and a considerable proportion also used FAS dosages ≥1000 μg/day.Action should be planned by the Health Care System and health professionals to improve the appropriate periconceptional use of FAS, taking into consideration the associated factors.

View Article: PubMed Central - PubMed

Affiliation: Departamento Salud Pública, Universidad Miguel Hernández, San Juan de Alicante, Spain CIBER de Epidemiología y Salud Pública (CIBERESP), Spain.

No MeSH data available.


Related in: MedlinePlus

Folic acid supplements use among 2422 participants in all cohorts of the INMA Project, Spain (2003-2008). Percentage by months of pregnancy.
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BMJOPEN2015009202F1: Folic acid supplements use among 2422 participants in all cohorts of the INMA Project, Spain (2003-2008). Percentage by months of pregnancy.

Mentions: Figure 1 shows the proportion of women using FAS during pregnancy. The percentage of women using FAS in preconception, the first, second and third month of pregnancy was 22.8%, 30.4%, 57.4% and 85.8%, respectively. The proportion of women using FAS in the periconceptional period was similar in the four geographical areas although significant differences were noted afterwards: women in Valencia and Asturias continued using FAS after the third month (84% and 95%, respectively), while most women in Guipuzcoa and Sabadell stopped (approximately 10% continued). Overall, 149 of the women did not take FAS at any time during pregnancy; most were from Sabadell and Guipuzcoa (89%). Considering the entire pregnancy, approximately one-third of the women reported the use of high dosages of FAS (≥1000 µg/day), although this proportion varied by geographical area: Asturias and Guipuzcoa showed higher percentages of women using FAS dosages ≥1000 µg/day than women from Sabadell and Valencia (data not show). The major sources of high dosages of FAS (≥1000 µg/day) were specific single folic acid preparations such as ACFOL (5000 µg/day) or ASPOL (10 000 µg/day).


Use of high doses of folic acid supplements in pregnant women in Spain: an INMA cohort study.

Navarrete-Muñoz EM, Valera-Gran D, García de la Hera M, Gimenez-Monzo D, Morales E, Julvez J, Riaño I, Tardón A, Ibarluzea J, Santa-Marina L, Murcia M, Rebagliato M, Vioque J, INMA Proje - BMJ Open (2015)

Folic acid supplements use among 2422 participants in all cohorts of the INMA Project, Spain (2003-2008). Percentage by months of pregnancy.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4663411&req=5

BMJOPEN2015009202F1: Folic acid supplements use among 2422 participants in all cohorts of the INMA Project, Spain (2003-2008). Percentage by months of pregnancy.
Mentions: Figure 1 shows the proportion of women using FAS during pregnancy. The percentage of women using FAS in preconception, the first, second and third month of pregnancy was 22.8%, 30.4%, 57.4% and 85.8%, respectively. The proportion of women using FAS in the periconceptional period was similar in the four geographical areas although significant differences were noted afterwards: women in Valencia and Asturias continued using FAS after the third month (84% and 95%, respectively), while most women in Guipuzcoa and Sabadell stopped (approximately 10% continued). Overall, 149 of the women did not take FAS at any time during pregnancy; most were from Sabadell and Guipuzcoa (89%). Considering the entire pregnancy, approximately one-third of the women reported the use of high dosages of FAS (≥1000 µg/day), although this proportion varied by geographical area: Asturias and Guipuzcoa showed higher percentages of women using FAS dosages ≥1000 µg/day than women from Sabadell and Valencia (data not show). The major sources of high dosages of FAS (≥1000 µg/day) were specific single folic acid preparations such as ACFOL (5000 µg/day) or ASPOL (10 000 µg/day).

Bottom Line: In the second period, only tobacco smoking was significantly associated with high FAS dosage use (RRR=0.67).A high proportion of pregnant women did not reach the recommended dosages of FAS in periconception and a considerable proportion also used FAS dosages ≥1000 μg/day.Action should be planned by the Health Care System and health professionals to improve the appropriate periconceptional use of FAS, taking into consideration the associated factors.

View Article: PubMed Central - PubMed

Affiliation: Departamento Salud Pública, Universidad Miguel Hernández, San Juan de Alicante, Spain CIBER de Epidemiología y Salud Pública (CIBERESP), Spain.

No MeSH data available.


Related in: MedlinePlus