Limits...
Market Assessment and Product Evaluation of Probiotic Containing Dietary Supplements Available in Bangladesh Market.

Begum AA, Jakaria DM, Anisuzzaman SM, Islam M, Mahmud SA - J Pharm (Cairo) (2015)

Bottom Line: These plates were then incubated at 37°C for 48 hours and colonies were counted.Legislation and regulation regarding prebiotic-probiotic containing products should be built up in Bangladesh to ensure quality products supply to the consumers.Moreover, manufacturers of probiotic containing products should take the responsibility for providing the consumer with scientifically and legally correct information.

View Article: PubMed Central - PubMed

Affiliation: Department of Pharmacy, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh.

ABSTRACT
Probiotics containing food supplements available in Bangladesh market were identified and collected for assessment. To assess their label claim, they were resuspended into sterile distilled water. Then, series dilutions of each sample solution were prepared and immediately plated out, in duplicate, into De Man Rogosa Sharpe (MRS) agar. These plates were then incubated at 37°C for 48 hours and colonies were counted. Viable cell numbers stated on the labels were compared with actual viable cell numbers. To assess the viability of the probiotics included in the products, probiotic strains were isolated from each of the four products and screened for inhibitory activity against six indicator strains. It was surprisingly found that although the viable cell numbers of all supplements were three to four log cycles lower than label claim of the products, however, this problem did not affect the inhibitory activity of the probiotic strains against indicator strains according to in vitro assessment. Legislation and regulation regarding prebiotic-probiotic containing products should be built up in Bangladesh to ensure quality products supply to the consumers. Moreover, manufacturers of probiotic containing products should take the responsibility for providing the consumer with scientifically and legally correct information.

No MeSH data available.


Related in: MedlinePlus

A partial presentation of growth of probiotics of four different products.
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC4663338&req=5

fig1: A partial presentation of growth of probiotics of four different products.

Mentions: The prebiotic and probiotic containing product market is a fast-growing industry worldwide and the list of available products increases on a daily basis. Although as a developing country, Bangladesh has limited scope and facility but is trying to cope up with the health demand of probiotic. One of the leading pharmaceutical companies has realized the importance of functional food and launched a probiotics product in capsule form. Throughout the world prebiotics and probiotics are available in fermented food like yoghurt and also in baby foods. Through the market assessment, different types of food products were found containing probiotics and combination of probiotics and prebiotics. Among them some are fortified baby food, dairy products, and yoghurt products. But only four food supplements were found in Bangladesh containing only probiotics. Among them one product is manufactured in Bangladesh and two capsules were from India and one sachet (powder) was from Taiwan. Three samples were of capsule form and only one was in powdered form available in sachet. But no food supplements were found having probiotic and prebiotic combination. All the four samples contained same probiotics like Lactobacillus acidophilus, Lactobacillus bulgaricus, Bifidobacterium bifidum, Lactobacillus salivarius, Lactobacillus casei, Bifidobacterium longum, Saccharomyces boulardii, Lactobacillus rhamnosus, Bifidobacterium infantis, Lactococcus lactis, Lactobacillus paracasei, and Streptococcus thermophilus but the viable cell numbers are different. As a functional food component, prebiotics and probiotics are conceptually intermediate between foods and drugs. Depending on the jurisdiction, they typically receive an intermediate level of regulatory scrutiny, in particular of the health claims made concerning them. For probiotic to exert beneficial properties, they must have a high viability in the product and have robust survival properties in the gut, which is their first point of contact [22]. That is why assessment of the label claim is necessary for these food products. Comparison of viable cell numbers stated on the labels of the supplements with the actual viable cell numbers is presented in Table 1 and Figure 1.


Market Assessment and Product Evaluation of Probiotic Containing Dietary Supplements Available in Bangladesh Market.

Begum AA, Jakaria DM, Anisuzzaman SM, Islam M, Mahmud SA - J Pharm (Cairo) (2015)

A partial presentation of growth of probiotics of four different products.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4663338&req=5

fig1: A partial presentation of growth of probiotics of four different products.
Mentions: The prebiotic and probiotic containing product market is a fast-growing industry worldwide and the list of available products increases on a daily basis. Although as a developing country, Bangladesh has limited scope and facility but is trying to cope up with the health demand of probiotic. One of the leading pharmaceutical companies has realized the importance of functional food and launched a probiotics product in capsule form. Throughout the world prebiotics and probiotics are available in fermented food like yoghurt and also in baby foods. Through the market assessment, different types of food products were found containing probiotics and combination of probiotics and prebiotics. Among them some are fortified baby food, dairy products, and yoghurt products. But only four food supplements were found in Bangladesh containing only probiotics. Among them one product is manufactured in Bangladesh and two capsules were from India and one sachet (powder) was from Taiwan. Three samples were of capsule form and only one was in powdered form available in sachet. But no food supplements were found having probiotic and prebiotic combination. All the four samples contained same probiotics like Lactobacillus acidophilus, Lactobacillus bulgaricus, Bifidobacterium bifidum, Lactobacillus salivarius, Lactobacillus casei, Bifidobacterium longum, Saccharomyces boulardii, Lactobacillus rhamnosus, Bifidobacterium infantis, Lactococcus lactis, Lactobacillus paracasei, and Streptococcus thermophilus but the viable cell numbers are different. As a functional food component, prebiotics and probiotics are conceptually intermediate between foods and drugs. Depending on the jurisdiction, they typically receive an intermediate level of regulatory scrutiny, in particular of the health claims made concerning them. For probiotic to exert beneficial properties, they must have a high viability in the product and have robust survival properties in the gut, which is their first point of contact [22]. That is why assessment of the label claim is necessary for these food products. Comparison of viable cell numbers stated on the labels of the supplements with the actual viable cell numbers is presented in Table 1 and Figure 1.

Bottom Line: These plates were then incubated at 37°C for 48 hours and colonies were counted.Legislation and regulation regarding prebiotic-probiotic containing products should be built up in Bangladesh to ensure quality products supply to the consumers.Moreover, manufacturers of probiotic containing products should take the responsibility for providing the consumer with scientifically and legally correct information.

View Article: PubMed Central - PubMed

Affiliation: Department of Pharmacy, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh.

ABSTRACT
Probiotics containing food supplements available in Bangladesh market were identified and collected for assessment. To assess their label claim, they were resuspended into sterile distilled water. Then, series dilutions of each sample solution were prepared and immediately plated out, in duplicate, into De Man Rogosa Sharpe (MRS) agar. These plates were then incubated at 37°C for 48 hours and colonies were counted. Viable cell numbers stated on the labels were compared with actual viable cell numbers. To assess the viability of the probiotics included in the products, probiotic strains were isolated from each of the four products and screened for inhibitory activity against six indicator strains. It was surprisingly found that although the viable cell numbers of all supplements were three to four log cycles lower than label claim of the products, however, this problem did not affect the inhibitory activity of the probiotic strains against indicator strains according to in vitro assessment. Legislation and regulation regarding prebiotic-probiotic containing products should be built up in Bangladesh to ensure quality products supply to the consumers. Moreover, manufacturers of probiotic containing products should take the responsibility for providing the consumer with scientifically and legally correct information.

No MeSH data available.


Related in: MedlinePlus