Limits...
One-Stage Reconstruction of Scalp after Full-Thickness Oncologic Defects Using a Dermal Regeneration Template (Integra).

De Angelis B, Gentile P, Tati E, Bottini DJ, Bocchini I, Orlandi F, Pepe G, Di Segni C, Cervelli G, Cervelli V - Biomed Res Int (2015)

Bottom Line: In group A, the excisions were performed to the galeal layer avoiding pericranium, and in group B the excisions were performed including pericranium layer with subsequent coverage of the exposed bone with local pericranial flap.In 3 weeks we observed the complete healing of the wound bed by secondary intention with acceptable cosmetic results and stable scars.Scalp reconstruction using a DRT is a valid coverage technique for minor and major scalp defects and it can be conducted with good results in elderly patients with multiple comorbidities.

View Article: PubMed Central - PubMed

Affiliation: Department of Plastic and Reconstructive Surgery, University of Rome "Tor Vergata", 00133 Rome, Italy.

ABSTRACT
The use of Dermal Regeneration Template (DRT) can be a valid alternative for scalp reconstruction, especially in elderly patients where a rapid procedure with an acceptable aesthetic and reliable functional outcome is required. We reviewed the surgical outcome of 20 patients, 14 (70%) males and 6 (30%) females, who underwent application of DRT for scalp reconstruction for small defects (group A: mean defect size of 12.51 cm(2)) and for large defects (group B: mean defect size of 28.7 cm(2)) after wide excision of scalp neoplasm (basal cell carcinoma and squamous cell carcinoma). In group A, the excisions were performed to the galeal layer avoiding pericranium, and in group B the excisions were performed including pericranium layer with subsequent coverage of the exposed bone with local pericranial flap. In both the groups (A and B) after the excision of the tumor, the wound bed was covered with Dermal Regeneration Template. In 3 weeks we observed the complete healing of the wound bed by secondary intention with acceptable cosmetic results and stable scars. Scalp reconstruction using a DRT is a valid coverage technique for minor and major scalp defects and it can be conducted with good results in elderly patients with multiple comorbidities.

No MeSH data available.


Related in: MedlinePlus

Histological analysis: (a) switching between skin covered by skin and ulcerated area, (b) side with the overlying skin epidermidis, (c) ulcerated area with underlying lattice partially amorphous material, and (d) higher magnification image 1 particularly of amorphous material.
© Copyright Policy
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4663323&req=5

fig9: Histological analysis: (a) switching between skin covered by skin and ulcerated area, (b) side with the overlying skin epidermidis, (c) ulcerated area with underlying lattice partially amorphous material, and (d) higher magnification image 1 particularly of amorphous material.

Mentions: Microscopic evaluation showed a progressive process of wound reepithelialization, starting from an ulcerated area with underlying lattice partially amorphous material (Figures 9(c) and 9(d)), proceeding through the formation of dermal granulation tissue rich in newly deposed vessels with overlying early migration of cheratinocytes with switching area between skin and wound (Figure 9(a)), and finally resulting in overlying skin epidermis.


One-Stage Reconstruction of Scalp after Full-Thickness Oncologic Defects Using a Dermal Regeneration Template (Integra).

De Angelis B, Gentile P, Tati E, Bottini DJ, Bocchini I, Orlandi F, Pepe G, Di Segni C, Cervelli G, Cervelli V - Biomed Res Int (2015)

Histological analysis: (a) switching between skin covered by skin and ulcerated area, (b) side with the overlying skin epidermidis, (c) ulcerated area with underlying lattice partially amorphous material, and (d) higher magnification image 1 particularly of amorphous material.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4663323&req=5

fig9: Histological analysis: (a) switching between skin covered by skin and ulcerated area, (b) side with the overlying skin epidermidis, (c) ulcerated area with underlying lattice partially amorphous material, and (d) higher magnification image 1 particularly of amorphous material.
Mentions: Microscopic evaluation showed a progressive process of wound reepithelialization, starting from an ulcerated area with underlying lattice partially amorphous material (Figures 9(c) and 9(d)), proceeding through the formation of dermal granulation tissue rich in newly deposed vessels with overlying early migration of cheratinocytes with switching area between skin and wound (Figure 9(a)), and finally resulting in overlying skin epidermis.

Bottom Line: In group A, the excisions were performed to the galeal layer avoiding pericranium, and in group B the excisions were performed including pericranium layer with subsequent coverage of the exposed bone with local pericranial flap.In 3 weeks we observed the complete healing of the wound bed by secondary intention with acceptable cosmetic results and stable scars.Scalp reconstruction using a DRT is a valid coverage technique for minor and major scalp defects and it can be conducted with good results in elderly patients with multiple comorbidities.

View Article: PubMed Central - PubMed

Affiliation: Department of Plastic and Reconstructive Surgery, University of Rome "Tor Vergata", 00133 Rome, Italy.

ABSTRACT
The use of Dermal Regeneration Template (DRT) can be a valid alternative for scalp reconstruction, especially in elderly patients where a rapid procedure with an acceptable aesthetic and reliable functional outcome is required. We reviewed the surgical outcome of 20 patients, 14 (70%) males and 6 (30%) females, who underwent application of DRT for scalp reconstruction for small defects (group A: mean defect size of 12.51 cm(2)) and for large defects (group B: mean defect size of 28.7 cm(2)) after wide excision of scalp neoplasm (basal cell carcinoma and squamous cell carcinoma). In group A, the excisions were performed to the galeal layer avoiding pericranium, and in group B the excisions were performed including pericranium layer with subsequent coverage of the exposed bone with local pericranial flap. In both the groups (A and B) after the excision of the tumor, the wound bed was covered with Dermal Regeneration Template. In 3 weeks we observed the complete healing of the wound bed by secondary intention with acceptable cosmetic results and stable scars. Scalp reconstruction using a DRT is a valid coverage technique for minor and major scalp defects and it can be conducted with good results in elderly patients with multiple comorbidities.

No MeSH data available.


Related in: MedlinePlus