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Syphilis: Is it making resurgence?

Shah BJ, Karia DR, Pawara CL - Indian J Sex Transm Dis (2015 Jul-Dec)

Bottom Line: Thorough sociodemographic, clinical, and investigational data were assessed and compared with the annual incidence of last 4 years.Twenty-seven (24.5%) patients were human immunodeficiency virus (HIV) reactive.The major risk factors considered are the HIV infection and homosexual behavior.

View Article: PubMed Central - PubMed

Affiliation: Department of Skin and VD, B.J. Medical College and Civil Hospital, Ahmedabad, Gujarat, India.

ABSTRACT

Background: Syphilis, the "great imitator", presents with a wide range of mucocutaneous and systemic manifestations, which can mimic many more diseases. Though there has been a rising prevalence of viral sexually transmitted infections (STIs), syphilis is not an uncommon diagnosis.

Aims: To study the recent trend of acquired syphilis in the patients attending STI clinic.

Materials and methods: Retrospective analysis of all the syphilis patients registered with STI clinic of our institute from January 2013 to December 2014 was done. Thorough sociodemographic, clinical, and investigational data were assessed and compared with the annual incidence of last 4 years.

Results: Of the total 1010 STI patients who attended the STI clinic, 110 cases were diagnosed as syphilis. There were 78 (70.9%) males and 32 (29.1%) females. Twenty-five (22.7%) patients were men who have sex with men (MSM). Primary syphilis was diagnosed in 28 (25.5%), secondary in 47 (42.7%), and latent in 35 (31.8%) cases. Lymphadenopathy was present in 55 (50%) patients with syphilis. Mixed infection was diagnosed in 29 (26.4%) patients of whom genital herpes was the most common. Twenty-seven (24.5%) patients were human immunodeficiency virus (HIV) reactive.

Conclusion: Incidence of syphilis has shown a rising trend over past few years. The major risk factors considered are the HIV infection and homosexual behavior.

No MeSH data available.


Related in: MedlinePlus

Palmoplantar syphilides in a patient with secondary syphilis (left) with concomitant chancroid (right)
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Figure 2: Palmoplantar syphilides in a patient with secondary syphilis (left) with concomitant chancroid (right)

Mentions: 42.7% (n = 47) patients were diagnosed as having secondary syphilis. Most of them presented with asymptomatic rash and condylomata lata, [Table 2], [Figure 1]. Other features included palmoplantar syphilides (n = 9), split papules (n = 7), mucous patches (n = 3), syphilitic cornee (n = 3), and lues maligna (n = 3) [Figure 2]. Thirty-five (31.8%) patients were diagnosed as having latent syphilis based on positive serology. Twenty-eight (25.5%) patients were diagnosed as having primary syphilis.


Syphilis: Is it making resurgence?

Shah BJ, Karia DR, Pawara CL - Indian J Sex Transm Dis (2015 Jul-Dec)

Palmoplantar syphilides in a patient with secondary syphilis (left) with concomitant chancroid (right)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4660560&req=5

Figure 2: Palmoplantar syphilides in a patient with secondary syphilis (left) with concomitant chancroid (right)
Mentions: 42.7% (n = 47) patients were diagnosed as having secondary syphilis. Most of them presented with asymptomatic rash and condylomata lata, [Table 2], [Figure 1]. Other features included palmoplantar syphilides (n = 9), split papules (n = 7), mucous patches (n = 3), syphilitic cornee (n = 3), and lues maligna (n = 3) [Figure 2]. Thirty-five (31.8%) patients were diagnosed as having latent syphilis based on positive serology. Twenty-eight (25.5%) patients were diagnosed as having primary syphilis.

Bottom Line: Thorough sociodemographic, clinical, and investigational data were assessed and compared with the annual incidence of last 4 years.Twenty-seven (24.5%) patients were human immunodeficiency virus (HIV) reactive.The major risk factors considered are the HIV infection and homosexual behavior.

View Article: PubMed Central - PubMed

Affiliation: Department of Skin and VD, B.J. Medical College and Civil Hospital, Ahmedabad, Gujarat, India.

ABSTRACT

Background: Syphilis, the "great imitator", presents with a wide range of mucocutaneous and systemic manifestations, which can mimic many more diseases. Though there has been a rising prevalence of viral sexually transmitted infections (STIs), syphilis is not an uncommon diagnosis.

Aims: To study the recent trend of acquired syphilis in the patients attending STI clinic.

Materials and methods: Retrospective analysis of all the syphilis patients registered with STI clinic of our institute from January 2013 to December 2014 was done. Thorough sociodemographic, clinical, and investigational data were assessed and compared with the annual incidence of last 4 years.

Results: Of the total 1010 STI patients who attended the STI clinic, 110 cases were diagnosed as syphilis. There were 78 (70.9%) males and 32 (29.1%) females. Twenty-five (22.7%) patients were men who have sex with men (MSM). Primary syphilis was diagnosed in 28 (25.5%), secondary in 47 (42.7%), and latent in 35 (31.8%) cases. Lymphadenopathy was present in 55 (50%) patients with syphilis. Mixed infection was diagnosed in 29 (26.4%) patients of whom genital herpes was the most common. Twenty-seven (24.5%) patients were human immunodeficiency virus (HIV) reactive.

Conclusion: Incidence of syphilis has shown a rising trend over past few years. The major risk factors considered are the HIV infection and homosexual behavior.

No MeSH data available.


Related in: MedlinePlus