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Prolene Canalostenting in Deep Sclerectomy: A Pilot Study.

Abdelrahman AM, El-Sayed YM - Middle East Afr J Ophthalmol (2015 Oct-Dec)

Bottom Line: Mean IOP decreased statistically significant from 19 ± 4.2 mmHg preoperatively to 12 mmHg at 15 months postoperatively (P < 0.0001).The number of glaucoma medications was reduced from 3.7 ± 0.7 preoperatively to 0 postoperatively.Implantation of a 5/0 prolene suture in Schlemm's canal during deep sclerectomy was a safe, cost-effective adjunct to maintain the patency of the intrascleral space and Schlemm's canal thus controlling IOP for 6 months postoperatively.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Faculty of Medicine, Cairo University, Cairo, Egypt.

ABSTRACT

Purpose: To study the effect of implantation of a 5/0 prolene suture segment inside Schlemm's canal as an adjunct to deep sclerectomy.

Materials and methods: This was a prospective, interventional case series of nine eyes of six patients with open angle glaucoma. Patients underwent deep sclerectomy with insertion of a segment of 5/0 prolene into Schlemm's canal at the filtration site without suturing. The main outcome measures were: Intraocular pressure (IOP), postoperative interventions, and complications. Ultrasound biomicroscopy of the filtration area as well as the prolene suture was performed at 6 months postoperatively.

Results: Patients were followed for a mean of 8.1 ± 4.5 months. Mean IOP decreased statistically significant from 19 ± 4.2 mmHg preoperatively to 12 mmHg at 15 months postoperatively (P < 0.0001). The number of glaucoma medications was reduced from 3.7 ± 0.7 preoperatively to 0 postoperatively. No postoperative complications were noted. IOP remained in the low teens in all patients out to the last postoperative visit. Yttrium-aluminum-garnet laser goniopuncture was not required in any case.

Conclusion: Implantation of a 5/0 prolene suture in Schlemm's canal during deep sclerectomy was a safe, cost-effective adjunct to maintain the patency of the intrascleral space and Schlemm's canal thus controlling IOP for 6 months postoperatively.

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Reduction of intraocular pressure during the postoperative period
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Figure 2: Reduction of intraocular pressure during the postoperative period

Mentions: This study included nine eyes of 6 patients aged 39.7 ± 20.4 years (range, 20 years to 72 years). The mean follow-up was 8.1 ± 4.5 months. There was a statistically significant reduction of intraocular pressure (IOP), from a mean of 19 mmHg preoperatively to 12 mmHg at 15 months postoperatively (P < 0.0001) [Figure 2]. None of the patients required medical therapy or yttrium-aluminum-garnet (YAG) laser goniopuncture to control IOP out to last postoperative follow-up.


Prolene Canalostenting in Deep Sclerectomy: A Pilot Study.

Abdelrahman AM, El-Sayed YM - Middle East Afr J Ophthalmol (2015 Oct-Dec)

Reduction of intraocular pressure during the postoperative period
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4660542&req=5

Figure 2: Reduction of intraocular pressure during the postoperative period
Mentions: This study included nine eyes of 6 patients aged 39.7 ± 20.4 years (range, 20 years to 72 years). The mean follow-up was 8.1 ± 4.5 months. There was a statistically significant reduction of intraocular pressure (IOP), from a mean of 19 mmHg preoperatively to 12 mmHg at 15 months postoperatively (P < 0.0001) [Figure 2]. None of the patients required medical therapy or yttrium-aluminum-garnet (YAG) laser goniopuncture to control IOP out to last postoperative follow-up.

Bottom Line: Mean IOP decreased statistically significant from 19 ± 4.2 mmHg preoperatively to 12 mmHg at 15 months postoperatively (P < 0.0001).The number of glaucoma medications was reduced from 3.7 ± 0.7 preoperatively to 0 postoperatively.Implantation of a 5/0 prolene suture in Schlemm's canal during deep sclerectomy was a safe, cost-effective adjunct to maintain the patency of the intrascleral space and Schlemm's canal thus controlling IOP for 6 months postoperatively.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Faculty of Medicine, Cairo University, Cairo, Egypt.

ABSTRACT

Purpose: To study the effect of implantation of a 5/0 prolene suture segment inside Schlemm's canal as an adjunct to deep sclerectomy.

Materials and methods: This was a prospective, interventional case series of nine eyes of six patients with open angle glaucoma. Patients underwent deep sclerectomy with insertion of a segment of 5/0 prolene into Schlemm's canal at the filtration site without suturing. The main outcome measures were: Intraocular pressure (IOP), postoperative interventions, and complications. Ultrasound biomicroscopy of the filtration area as well as the prolene suture was performed at 6 months postoperatively.

Results: Patients were followed for a mean of 8.1 ± 4.5 months. Mean IOP decreased statistically significant from 19 ± 4.2 mmHg preoperatively to 12 mmHg at 15 months postoperatively (P < 0.0001). The number of glaucoma medications was reduced from 3.7 ± 0.7 preoperatively to 0 postoperatively. No postoperative complications were noted. IOP remained in the low teens in all patients out to the last postoperative visit. Yttrium-aluminum-garnet laser goniopuncture was not required in any case.

Conclusion: Implantation of a 5/0 prolene suture in Schlemm's canal during deep sclerectomy was a safe, cost-effective adjunct to maintain the patency of the intrascleral space and Schlemm's canal thus controlling IOP for 6 months postoperatively.

Show MeSH
Related in: MedlinePlus