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Parity and Risk of Stroke among Chinese Women: Cross-sectional Evidence from the Dongfeng-Tongji Cohort Study.

Zhang Y, Shen L, Wu J, Xu G, Song L, Yang S, Tian Y, Yuan J, Liang Y, Wang Y - Sci Rep (2015)

Bottom Line: We used data from the Dongfeng-Tongji Cohort Study.In total, 14,277 women were included in the analysis.Participants were classified into four groups according to parity.

View Article: PubMed Central - PubMed

Affiliation: MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science &Technology, Wuhan, China.

ABSTRACT
Epidemiological studies have investigated the association between parity and the risk of stroke, but the results have been inconsistent. The objective of this study was to assess the association among middle-aged and older Chinese women. We used data from the Dongfeng-Tongji Cohort Study. In total, 14,277 women were included in the analysis. Participants were classified into four groups according to parity. Stroke cases were self-reported during face-to-face interviews. Multivariable logistic regression models were used to investigate the association between parity and the risk of stroke while controlling for potential confounders. The prevalence of stroke among the study subjects was 2.7% (380 of 14,277). In the fully adjusted model, women who had experienced two, three, or four or more live births had 1.24 times (95% CI, 0.85-1.81), 1.97 times (95% CI, 1.30-2.98) and 1.86 times (95% CI, 1.14-3.03), higher risk of stroke, respectively, compared with women who had experienced one live birth. High parity was associated with an increasing risk of stroke in the present study. Further longitudinal studies are needed to confirm the association and to explore the unclear mechanism underlying the link between parity and stroke risk.

No MeSH data available.


Related in: MedlinePlus

Presents the fully-adjusted prevalence of stroke in women by parity.Every circle represents the point estimation value of stroke prevalence and every range line represents the 95% confidence interval.
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f2: Presents the fully-adjusted prevalence of stroke in women by parity.Every circle represents the point estimation value of stroke prevalence and every range line represents the 95% confidence interval.

Mentions: The age-adjusted and fully adjusted prevalence of stroke is presented by parity in Figs 1 and 2 respectively. In Fig. 1, the age-adjusted prevalence of stroke was higher for each increasing parity group. The fully adjusted prevalence of stroke (Fig. 2) increased from the one live birth group to the three live births group, but declined slowly in the group with four or more live births. However, the prevalence of stroke was still higher among those with four or more live births than among those with one or two live births.


Parity and Risk of Stroke among Chinese Women: Cross-sectional Evidence from the Dongfeng-Tongji Cohort Study.

Zhang Y, Shen L, Wu J, Xu G, Song L, Yang S, Tian Y, Yuan J, Liang Y, Wang Y - Sci Rep (2015)

Presents the fully-adjusted prevalence of stroke in women by parity.Every circle represents the point estimation value of stroke prevalence and every range line represents the 95% confidence interval.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4660279&req=5

f2: Presents the fully-adjusted prevalence of stroke in women by parity.Every circle represents the point estimation value of stroke prevalence and every range line represents the 95% confidence interval.
Mentions: The age-adjusted and fully adjusted prevalence of stroke is presented by parity in Figs 1 and 2 respectively. In Fig. 1, the age-adjusted prevalence of stroke was higher for each increasing parity group. The fully adjusted prevalence of stroke (Fig. 2) increased from the one live birth group to the three live births group, but declined slowly in the group with four or more live births. However, the prevalence of stroke was still higher among those with four or more live births than among those with one or two live births.

Bottom Line: We used data from the Dongfeng-Tongji Cohort Study.In total, 14,277 women were included in the analysis.Participants were classified into four groups according to parity.

View Article: PubMed Central - PubMed

Affiliation: MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science &Technology, Wuhan, China.

ABSTRACT
Epidemiological studies have investigated the association between parity and the risk of stroke, but the results have been inconsistent. The objective of this study was to assess the association among middle-aged and older Chinese women. We used data from the Dongfeng-Tongji Cohort Study. In total, 14,277 women were included in the analysis. Participants were classified into four groups according to parity. Stroke cases were self-reported during face-to-face interviews. Multivariable logistic regression models were used to investigate the association between parity and the risk of stroke while controlling for potential confounders. The prevalence of stroke among the study subjects was 2.7% (380 of 14,277). In the fully adjusted model, women who had experienced two, three, or four or more live births had 1.24 times (95% CI, 0.85-1.81), 1.97 times (95% CI, 1.30-2.98) and 1.86 times (95% CI, 1.14-3.03), higher risk of stroke, respectively, compared with women who had experienced one live birth. High parity was associated with an increasing risk of stroke in the present study. Further longitudinal studies are needed to confirm the association and to explore the unclear mechanism underlying the link between parity and stroke risk.

No MeSH data available.


Related in: MedlinePlus