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Psycho-education for substance use and antisocial personality disorder: a randomized trial.

Thylstrup B, Schrøder S, Hesse M - BMC Psychiatry (2015)

Bottom Line: All patients reduced drug and alcohol problems at 9 months with small within-group effect sizes.Intention-to-treat analyses indicated significant differences between ILC and TAU in mean drugs composite score (p = .018) and in PDA (p = .041) at 3 months.ISRCTN registry, ISRCTN67266318 , 17/7/2012.

View Article: PubMed Central - PubMed

Affiliation: Centre for Alcohol and Drug Research, Aarhus University, Artillerivej 90, 2nd, 2300, Copenhagen S, Denmark. bt.crf@psy.au.dk.

ABSTRACT

Background: Antisocial personality disorder often co-exists with drug and alcohol use disorders.

Methods: This trial examined the effectiveness of offering psycho-education for antisocial personality disorder in community substance use disorder treatment centers in Denmark. A total of 176 patients were randomly allocated to treatment as usual (TAU, n = 80) or TAU plus a psycho-educative program, Impulsive Lifestyle Counselling (ILC, n = 96) delivered by site clinicians (n = 39). Using follow-up interviews 3 and 9 months after randomization, we examined changes in drug and alcohol use (Addiction Severity Index Composite Scores), percent days abstinent (PDA) within last month, and aggression as measured with the Buss-Perry Aggression Questionnaire-Short Form and the Self-Report of Aggression and Social Behavior Measure.

Results: Overall engagement in psychological interventions was modest: 71 (76 %) of participants randomized to psycho-education attended at least one counselling session, and 21 (23 %) attended all six sessions. The Median number of sessions was 2. All patients reduced drug and alcohol problems at 9 months with small within-group effect sizes. Intention-to-treat analyses indicated significant differences between ILC and TAU in mean drugs composite score (p = .018) and in PDA (p = .041) at 3 months. Aggression declined in both groups, but no differences between ILC and TAU were observed in terms of alcohol problems or aggression at any follow-up.

Conclusions: Moderate short-term improvements in substance use were associated with randomization to Impulsive Lifestyle Counselling. The findings support the usefulness of providing psycho-education to outpatients with antisocial personality disorder.

Trial registration: ISRCTN registry, ISRCTN67266318 , 17/7/2012.

No MeSH data available.


Related in: MedlinePlus

Flow diagram
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Related In: Results  -  Collection

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Fig1: Flow diagram

Mentions: The flow of patients through the trial is illustrated in Fig. 1.Fig. 1


Psycho-education for substance use and antisocial personality disorder: a randomized trial.

Thylstrup B, Schrøder S, Hesse M - BMC Psychiatry (2015)

Flow diagram
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4647713&req=5

Fig1: Flow diagram
Mentions: The flow of patients through the trial is illustrated in Fig. 1.Fig. 1

Bottom Line: All patients reduced drug and alcohol problems at 9 months with small within-group effect sizes.Intention-to-treat analyses indicated significant differences between ILC and TAU in mean drugs composite score (p = .018) and in PDA (p = .041) at 3 months.ISRCTN registry, ISRCTN67266318 , 17/7/2012.

View Article: PubMed Central - PubMed

Affiliation: Centre for Alcohol and Drug Research, Aarhus University, Artillerivej 90, 2nd, 2300, Copenhagen S, Denmark. bt.crf@psy.au.dk.

ABSTRACT

Background: Antisocial personality disorder often co-exists with drug and alcohol use disorders.

Methods: This trial examined the effectiveness of offering psycho-education for antisocial personality disorder in community substance use disorder treatment centers in Denmark. A total of 176 patients were randomly allocated to treatment as usual (TAU, n = 80) or TAU plus a psycho-educative program, Impulsive Lifestyle Counselling (ILC, n = 96) delivered by site clinicians (n = 39). Using follow-up interviews 3 and 9 months after randomization, we examined changes in drug and alcohol use (Addiction Severity Index Composite Scores), percent days abstinent (PDA) within last month, and aggression as measured with the Buss-Perry Aggression Questionnaire-Short Form and the Self-Report of Aggression and Social Behavior Measure.

Results: Overall engagement in psychological interventions was modest: 71 (76 %) of participants randomized to psycho-education attended at least one counselling session, and 21 (23 %) attended all six sessions. The Median number of sessions was 2. All patients reduced drug and alcohol problems at 9 months with small within-group effect sizes. Intention-to-treat analyses indicated significant differences between ILC and TAU in mean drugs composite score (p = .018) and in PDA (p = .041) at 3 months. Aggression declined in both groups, but no differences between ILC and TAU were observed in terms of alcohol problems or aggression at any follow-up.

Conclusions: Moderate short-term improvements in substance use were associated with randomization to Impulsive Lifestyle Counselling. The findings support the usefulness of providing psycho-education to outpatients with antisocial personality disorder.

Trial registration: ISRCTN registry, ISRCTN67266318 , 17/7/2012.

No MeSH data available.


Related in: MedlinePlus