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Subtraction MR Venography Acquired from Time-Resolved Contrast-Enhanced MR Angiography: Comparison with Phase-Contrast MR Venography and Single-Phase Contrast-Enhanced MR Venography.

Jang J, Kim BS, Sung J, Kim BY, Choi HS, Jung SL, Ahn KJ - Korean J Radiol (2015)

Bottom Line: Image quality and the degree of arterial contamination of the three MRVs were compared.The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of the three MRVs were also compared.The dural sinus score of SMRV (median and interquartile range [IQR] 48, 43-50 for reviewer 1, 47, 43-49 for reviewer 2) was significantly higher than for PCMRV (median and IQR 31, 25-34 for reviewer 1, 30, 23-32 for reviewer 2) (p < 0.01) and did not differ from that of CEMRV (median and IQR 50, 47-52 for reviewer 1, 49, 45-51 for reviewer 2) (p = 0.146 in reviewer 1 and 0.123 in reviewer 2).

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.

ABSTRACT

Objective: To evaluate the image characteristics of subtraction magnetic resonance venography (SMRV) from time-resolved contrast-enhanced MR angiography (TRMRA) compared with phase-contrast MR venography (PCMRV) and single-phase contrast-enhanced MR venography (CEMRV).

Materials and methods: Twenty-one patients who underwent brain MR venography (MRV) using standard protocols (PCMRV, CEMRV, and TRMRA) were included. SMRV was made by subtracting the arterial phase data from the venous phase data in TRMRA. Co-registration and subtraction of the two volume data was done using commercially available software. Image quality and the degree of arterial contamination of the three MRVs were compared. In the three MRVs, 19 pre-defined venous structures (14 dural sinuses and 5 cerebral veins) were evaluated. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of the three MRVs were also compared.

Results: Single-phase contrast-enhanced MR venography showed better image quality (median score 4 in both reviewers) than did the other two MRVs (p < 0.001), whereas SMRV (median score 3 in both reviewers) and PCMRV (median score 3 in both reviewers) had similar image quality (p ≥ 0.951). SMRV (median score 0 in both reviewers) suppressed arterial signal better than did the other MRVs (median score 1 in CEMRV, median score 2 in PCMRV, both reviewers) (p < 0.001). The dural sinus score of SMRV (median and interquartile range [IQR] 48, 43-50 for reviewer 1, 47, 43-49 for reviewer 2) was significantly higher than for PCMRV (median and IQR 31, 25-34 for reviewer 1, 30, 23-32 for reviewer 2) (p < 0.01) and did not differ from that of CEMRV (median and IQR 50, 47-52 for reviewer 1, 49, 45-51 for reviewer 2) (p = 0.146 in reviewer 1 and 0.123 in reviewer 2). The SNR and CNR of SMRV (median and IQR 104.5, 83.1-121.2 and 104.1, 74.9-120.5, respectively) were between those of CEMRV (median and IQR 150.3, 111-182.6 and 148.4, 108-178.2) and PCMRV (median and IQR 59.4, 49.2-74.9 and 53.6, 43.8-69.2).

Conclusion: Subtraction magnetic resonance venography is a promising MRV method, with acceptable image quality and good arterial suppression.

No MeSH data available.


Related in: MedlinePlus

Box plot of reviewer 1's cerebral vein and dural sinus scores of three MRVs.Presented P values were obtained from post hoc test (Wilcoxon signed rank test with Bonferroni correction). CEMRV = single-phase contrast-enhanced MR venography, MRV = MR venography, PCMRV = phase-contrast MR venography, SMRV = subtraction MR venography
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Figure 2: Box plot of reviewer 1's cerebral vein and dural sinus scores of three MRVs.Presented P values were obtained from post hoc test (Wilcoxon signed rank test with Bonferroni correction). CEMRV = single-phase contrast-enhanced MR venography, MRV = MR venography, PCMRV = phase-contrast MR venography, SMRV = subtraction MR venography

Mentions: There were significant differences in total vein scores, dural sinus scores and cerebral vein scores in the three MRVs (Table 2). Post hoc tests revealed the highest total vein scores for CEMRV (median and IQR 68, 63-70 and 66, 61-70 in reviewer 1 and 2, respectively), which were significantly different from the other MRVs in both reviewers. In addition, SMRV (median and IQR 62, 60-67 in reviewer 1, 63, 57-64 in reviewer 2) had significantly higher total vein scores than PCMRV (39, 34-45 and 37, 32-42 in each reviewer, respectively). This tendency was same in cerebral vein score. In contrast, the dural sinus scores of SMRV (median and IQR 48, 43-50 in reviewer 1, 47, 43-49 in reviewer 2) and CEMRV (median and IQR 50, 47-52 in reviewer 1, 49, 45-51 in reviewer 2) were not significantly different in the post hoc test (p = 0.146 in reviewer 1 and p = 0.121 in reviewer 2). Dural sinus scores of CEMRV and PCMRV (median and IQR 31, 25-34 in reviewer 1, 30, 23-32 in reviewer 2) were significantly different (Fig. 2).


Subtraction MR Venography Acquired from Time-Resolved Contrast-Enhanced MR Angiography: Comparison with Phase-Contrast MR Venography and Single-Phase Contrast-Enhanced MR Venography.

Jang J, Kim BS, Sung J, Kim BY, Choi HS, Jung SL, Ahn KJ - Korean J Radiol (2015)

Box plot of reviewer 1's cerebral vein and dural sinus scores of three MRVs.Presented P values were obtained from post hoc test (Wilcoxon signed rank test with Bonferroni correction). CEMRV = single-phase contrast-enhanced MR venography, MRV = MR venography, PCMRV = phase-contrast MR venography, SMRV = subtraction MR venography
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4644759&req=5

Figure 2: Box plot of reviewer 1's cerebral vein and dural sinus scores of three MRVs.Presented P values were obtained from post hoc test (Wilcoxon signed rank test with Bonferroni correction). CEMRV = single-phase contrast-enhanced MR venography, MRV = MR venography, PCMRV = phase-contrast MR venography, SMRV = subtraction MR venography
Mentions: There were significant differences in total vein scores, dural sinus scores and cerebral vein scores in the three MRVs (Table 2). Post hoc tests revealed the highest total vein scores for CEMRV (median and IQR 68, 63-70 and 66, 61-70 in reviewer 1 and 2, respectively), which were significantly different from the other MRVs in both reviewers. In addition, SMRV (median and IQR 62, 60-67 in reviewer 1, 63, 57-64 in reviewer 2) had significantly higher total vein scores than PCMRV (39, 34-45 and 37, 32-42 in each reviewer, respectively). This tendency was same in cerebral vein score. In contrast, the dural sinus scores of SMRV (median and IQR 48, 43-50 in reviewer 1, 47, 43-49 in reviewer 2) and CEMRV (median and IQR 50, 47-52 in reviewer 1, 49, 45-51 in reviewer 2) were not significantly different in the post hoc test (p = 0.146 in reviewer 1 and p = 0.121 in reviewer 2). Dural sinus scores of CEMRV and PCMRV (median and IQR 31, 25-34 in reviewer 1, 30, 23-32 in reviewer 2) were significantly different (Fig. 2).

Bottom Line: Image quality and the degree of arterial contamination of the three MRVs were compared.The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of the three MRVs were also compared.The dural sinus score of SMRV (median and interquartile range [IQR] 48, 43-50 for reviewer 1, 47, 43-49 for reviewer 2) was significantly higher than for PCMRV (median and IQR 31, 25-34 for reviewer 1, 30, 23-32 for reviewer 2) (p < 0.01) and did not differ from that of CEMRV (median and IQR 50, 47-52 for reviewer 1, 49, 45-51 for reviewer 2) (p = 0.146 in reviewer 1 and 0.123 in reviewer 2).

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.

ABSTRACT

Objective: To evaluate the image characteristics of subtraction magnetic resonance venography (SMRV) from time-resolved contrast-enhanced MR angiography (TRMRA) compared with phase-contrast MR venography (PCMRV) and single-phase contrast-enhanced MR venography (CEMRV).

Materials and methods: Twenty-one patients who underwent brain MR venography (MRV) using standard protocols (PCMRV, CEMRV, and TRMRA) were included. SMRV was made by subtracting the arterial phase data from the venous phase data in TRMRA. Co-registration and subtraction of the two volume data was done using commercially available software. Image quality and the degree of arterial contamination of the three MRVs were compared. In the three MRVs, 19 pre-defined venous structures (14 dural sinuses and 5 cerebral veins) were evaluated. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of the three MRVs were also compared.

Results: Single-phase contrast-enhanced MR venography showed better image quality (median score 4 in both reviewers) than did the other two MRVs (p < 0.001), whereas SMRV (median score 3 in both reviewers) and PCMRV (median score 3 in both reviewers) had similar image quality (p ≥ 0.951). SMRV (median score 0 in both reviewers) suppressed arterial signal better than did the other MRVs (median score 1 in CEMRV, median score 2 in PCMRV, both reviewers) (p < 0.001). The dural sinus score of SMRV (median and interquartile range [IQR] 48, 43-50 for reviewer 1, 47, 43-49 for reviewer 2) was significantly higher than for PCMRV (median and IQR 31, 25-34 for reviewer 1, 30, 23-32 for reviewer 2) (p < 0.01) and did not differ from that of CEMRV (median and IQR 50, 47-52 for reviewer 1, 49, 45-51 for reviewer 2) (p = 0.146 in reviewer 1 and 0.123 in reviewer 2). The SNR and CNR of SMRV (median and IQR 104.5, 83.1-121.2 and 104.1, 74.9-120.5, respectively) were between those of CEMRV (median and IQR 150.3, 111-182.6 and 148.4, 108-178.2) and PCMRV (median and IQR 59.4, 49.2-74.9 and 53.6, 43.8-69.2).

Conclusion: Subtraction magnetic resonance venography is a promising MRV method, with acceptable image quality and good arterial suppression.

No MeSH data available.


Related in: MedlinePlus