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Subtraction MR Venography Acquired from Time-Resolved Contrast-Enhanced MR Angiography: Comparison with Phase-Contrast MR Venography and Single-Phase Contrast-Enhanced MR Venography.

Jang J, Kim BS, Sung J, Kim BY, Choi HS, Jung SL, Ahn KJ - Korean J Radiol (2015)

Bottom Line: Image quality and the degree of arterial contamination of the three MRVs were compared.The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of the three MRVs were also compared.The dural sinus score of SMRV (median and interquartile range [IQR] 48, 43-50 for reviewer 1, 47, 43-49 for reviewer 2) was significantly higher than for PCMRV (median and IQR 31, 25-34 for reviewer 1, 30, 23-32 for reviewer 2) (p < 0.01) and did not differ from that of CEMRV (median and IQR 50, 47-52 for reviewer 1, 49, 45-51 for reviewer 2) (p = 0.146 in reviewer 1 and 0.123 in reviewer 2).

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.

ABSTRACT

Objective: To evaluate the image characteristics of subtraction magnetic resonance venography (SMRV) from time-resolved contrast-enhanced MR angiography (TRMRA) compared with phase-contrast MR venography (PCMRV) and single-phase contrast-enhanced MR venography (CEMRV).

Materials and methods: Twenty-one patients who underwent brain MR venography (MRV) using standard protocols (PCMRV, CEMRV, and TRMRA) were included. SMRV was made by subtracting the arterial phase data from the venous phase data in TRMRA. Co-registration and subtraction of the two volume data was done using commercially available software. Image quality and the degree of arterial contamination of the three MRVs were compared. In the three MRVs, 19 pre-defined venous structures (14 dural sinuses and 5 cerebral veins) were evaluated. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of the three MRVs were also compared.

Results: Single-phase contrast-enhanced MR venography showed better image quality (median score 4 in both reviewers) than did the other two MRVs (p < 0.001), whereas SMRV (median score 3 in both reviewers) and PCMRV (median score 3 in both reviewers) had similar image quality (p ≥ 0.951). SMRV (median score 0 in both reviewers) suppressed arterial signal better than did the other MRVs (median score 1 in CEMRV, median score 2 in PCMRV, both reviewers) (p < 0.001). The dural sinus score of SMRV (median and interquartile range [IQR] 48, 43-50 for reviewer 1, 47, 43-49 for reviewer 2) was significantly higher than for PCMRV (median and IQR 31, 25-34 for reviewer 1, 30, 23-32 for reviewer 2) (p < 0.01) and did not differ from that of CEMRV (median and IQR 50, 47-52 for reviewer 1, 49, 45-51 for reviewer 2) (p = 0.146 in reviewer 1 and 0.123 in reviewer 2). The SNR and CNR of SMRV (median and IQR 104.5, 83.1-121.2 and 104.1, 74.9-120.5, respectively) were between those of CEMRV (median and IQR 150.3, 111-182.6 and 148.4, 108-178.2) and PCMRV (median and IQR 59.4, 49.2-74.9 and 53.6, 43.8-69.2).

Conclusion: Subtraction magnetic resonance venography is a promising MRV method, with acceptable image quality and good arterial suppression.

No MeSH data available.


Related in: MedlinePlus

Representative case for choosing optimal phase for SMRV from TRMRA of 64-year-old female.On time-intensity curve (D) of right common carotid artery (CCA; black curve, white circle in B) and internal jugular vein (IJV; gray curve, black circle in B), signal characteristics of phases A and B were identified. Phase A (A) corresponds to time point of start of venous opacification (thin line), not arterial peak phase (dashed line). Phase B (thick line) had maximum venous structure signal. Phase B (B) shows substantial arterial signal, which is not desirable in MRV images. Acquired SMRV (C) image shows that arterial signal was clearly removed and cavernous and inferior petrosal sinuses were clearly visualized. SMRV = subtraction MR venography, TRMRA = time-resolved contrast-enhanced MR angiography
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Figure 1: Representative case for choosing optimal phase for SMRV from TRMRA of 64-year-old female.On time-intensity curve (D) of right common carotid artery (CCA; black curve, white circle in B) and internal jugular vein (IJV; gray curve, black circle in B), signal characteristics of phases A and B were identified. Phase A (A) corresponds to time point of start of venous opacification (thin line), not arterial peak phase (dashed line). Phase B (thick line) had maximum venous structure signal. Phase B (B) shows substantial arterial signal, which is not desirable in MRV images. Acquired SMRV (C) image shows that arterial signal was clearly removed and cavernous and inferior petrosal sinuses were clearly visualized. SMRV = subtraction MR venography, TRMRA = time-resolved contrast-enhanced MR angiography

Mentions: Subtraction MR venography was obtained by post-processing the TRMRA data. After reviewing the time-series of the coronal and sagittal maximal intensity projection (MIP) TRMRA images, a neuroradiologist chose two phases from each patient's TRMRA (Fig. 1A, B), a phase just before the visualization of the right internal jugular vein (phase A; Fig. 1A, thin line on Fig. 1D) and another phase with peak opacification of the right internal jugular vein (phase B; Fig. 1B, thick line on Fig. 1D). The A and B phases were selected for each patient based on the evaluation of his or her TRMRA images with 30 mm3 region of interest (ROI) on the mid-portion of the right internal jugular vein (black circle on Fig. 1B). After automated co-registration of the volume data for those two phases, a voxel-by-voxel subtraction was performed (phase B-phase A). Negative values were considered zero. Acquired volume data were used for variable image reconstructions, such as rotational MIP images (Fig. 1C) and thin slice multi-planar reformation (MPR) images. Image data were processed using commercially available software (Aquarius iNtuition, TeraRecon, Inc., Foster City, CA, USA).


Subtraction MR Venography Acquired from Time-Resolved Contrast-Enhanced MR Angiography: Comparison with Phase-Contrast MR Venography and Single-Phase Contrast-Enhanced MR Venography.

Jang J, Kim BS, Sung J, Kim BY, Choi HS, Jung SL, Ahn KJ - Korean J Radiol (2015)

Representative case for choosing optimal phase for SMRV from TRMRA of 64-year-old female.On time-intensity curve (D) of right common carotid artery (CCA; black curve, white circle in B) and internal jugular vein (IJV; gray curve, black circle in B), signal characteristics of phases A and B were identified. Phase A (A) corresponds to time point of start of venous opacification (thin line), not arterial peak phase (dashed line). Phase B (thick line) had maximum venous structure signal. Phase B (B) shows substantial arterial signal, which is not desirable in MRV images. Acquired SMRV (C) image shows that arterial signal was clearly removed and cavernous and inferior petrosal sinuses were clearly visualized. SMRV = subtraction MR venography, TRMRA = time-resolved contrast-enhanced MR angiography
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4644759&req=5

Figure 1: Representative case for choosing optimal phase for SMRV from TRMRA of 64-year-old female.On time-intensity curve (D) of right common carotid artery (CCA; black curve, white circle in B) and internal jugular vein (IJV; gray curve, black circle in B), signal characteristics of phases A and B were identified. Phase A (A) corresponds to time point of start of venous opacification (thin line), not arterial peak phase (dashed line). Phase B (thick line) had maximum venous structure signal. Phase B (B) shows substantial arterial signal, which is not desirable in MRV images. Acquired SMRV (C) image shows that arterial signal was clearly removed and cavernous and inferior petrosal sinuses were clearly visualized. SMRV = subtraction MR venography, TRMRA = time-resolved contrast-enhanced MR angiography
Mentions: Subtraction MR venography was obtained by post-processing the TRMRA data. After reviewing the time-series of the coronal and sagittal maximal intensity projection (MIP) TRMRA images, a neuroradiologist chose two phases from each patient's TRMRA (Fig. 1A, B), a phase just before the visualization of the right internal jugular vein (phase A; Fig. 1A, thin line on Fig. 1D) and another phase with peak opacification of the right internal jugular vein (phase B; Fig. 1B, thick line on Fig. 1D). The A and B phases were selected for each patient based on the evaluation of his or her TRMRA images with 30 mm3 region of interest (ROI) on the mid-portion of the right internal jugular vein (black circle on Fig. 1B). After automated co-registration of the volume data for those two phases, a voxel-by-voxel subtraction was performed (phase B-phase A). Negative values were considered zero. Acquired volume data were used for variable image reconstructions, such as rotational MIP images (Fig. 1C) and thin slice multi-planar reformation (MPR) images. Image data were processed using commercially available software (Aquarius iNtuition, TeraRecon, Inc., Foster City, CA, USA).

Bottom Line: Image quality and the degree of arterial contamination of the three MRVs were compared.The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of the three MRVs were also compared.The dural sinus score of SMRV (median and interquartile range [IQR] 48, 43-50 for reviewer 1, 47, 43-49 for reviewer 2) was significantly higher than for PCMRV (median and IQR 31, 25-34 for reviewer 1, 30, 23-32 for reviewer 2) (p < 0.01) and did not differ from that of CEMRV (median and IQR 50, 47-52 for reviewer 1, 49, 45-51 for reviewer 2) (p = 0.146 in reviewer 1 and 0.123 in reviewer 2).

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.

ABSTRACT

Objective: To evaluate the image characteristics of subtraction magnetic resonance venography (SMRV) from time-resolved contrast-enhanced MR angiography (TRMRA) compared with phase-contrast MR venography (PCMRV) and single-phase contrast-enhanced MR venography (CEMRV).

Materials and methods: Twenty-one patients who underwent brain MR venography (MRV) using standard protocols (PCMRV, CEMRV, and TRMRA) were included. SMRV was made by subtracting the arterial phase data from the venous phase data in TRMRA. Co-registration and subtraction of the two volume data was done using commercially available software. Image quality and the degree of arterial contamination of the three MRVs were compared. In the three MRVs, 19 pre-defined venous structures (14 dural sinuses and 5 cerebral veins) were evaluated. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of the three MRVs were also compared.

Results: Single-phase contrast-enhanced MR venography showed better image quality (median score 4 in both reviewers) than did the other two MRVs (p < 0.001), whereas SMRV (median score 3 in both reviewers) and PCMRV (median score 3 in both reviewers) had similar image quality (p ≥ 0.951). SMRV (median score 0 in both reviewers) suppressed arterial signal better than did the other MRVs (median score 1 in CEMRV, median score 2 in PCMRV, both reviewers) (p < 0.001). The dural sinus score of SMRV (median and interquartile range [IQR] 48, 43-50 for reviewer 1, 47, 43-49 for reviewer 2) was significantly higher than for PCMRV (median and IQR 31, 25-34 for reviewer 1, 30, 23-32 for reviewer 2) (p < 0.01) and did not differ from that of CEMRV (median and IQR 50, 47-52 for reviewer 1, 49, 45-51 for reviewer 2) (p = 0.146 in reviewer 1 and 0.123 in reviewer 2). The SNR and CNR of SMRV (median and IQR 104.5, 83.1-121.2 and 104.1, 74.9-120.5, respectively) were between those of CEMRV (median and IQR 150.3, 111-182.6 and 148.4, 108-178.2) and PCMRV (median and IQR 59.4, 49.2-74.9 and 53.6, 43.8-69.2).

Conclusion: Subtraction magnetic resonance venography is a promising MRV method, with acceptable image quality and good arterial suppression.

No MeSH data available.


Related in: MedlinePlus