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Colonic Metastasis Presenting as an Intraluminal Fungating Mass 8 Years After Surgery for Ovarian Cancer.

Kim JR, Kim BM, Kim YM, Lee WA, Namgung H - Ann Coloproctol (2015)

Bottom Line: We report a case of colonic metastasis from ovarian cancer presented as an intraluminal fungating mass mimicking primary colon cancer 8 years after surgery for ovarian cancer.A 70-year-old woman presented with constipation.A computed tomography scan showed a bulky intraluminal fungating mass in the rectosigmoid junction.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Dankook University College of Medicine, Cheonan, Korea.

ABSTRACT
We report a case of colonic metastasis from ovarian cancer presented as an intraluminal fungating mass mimicking primary colon cancer 8 years after surgery for ovarian cancer. A 70-year-old woman presented with constipation. She had undergone an extended total abdominal hysterectomy with bilateral salpingo-oophorectomy for an ovarian papillary serous cystadenocarcinoma 8 years earlier. Colonoscopy showed a large fungating mass 10 cm from the anal verge that was suspected to be colorectal cancer. A computed tomography scan showed a bulky intraluminal fungating mass in the rectosigmoid junction. After a lower anterior resection and a pathologic diagnosis, a diagnosis of a papillary serous adenocarcinoma due to metastasis from an ovarian tumor was made for this patient.

No MeSH data available.


Related in: MedlinePlus

The colonic mucosa shows a huge fungating tumor simulating the primary colon cancer.
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Figure 3: The colonic mucosa shows a huge fungating tumor simulating the primary colon cancer.

Mentions: The patient underwent a lower anterior resection with lymphnode dissection for the regional and the para-aortic lymph nodes. A 6-cm intraluminal mass was noted in the rectosigmoid junction with no evidence of a peritoneal seeding nodule in the pelvic and the abdominal cavities. Macroscopically, the mucosa revealed a huge fungating tumor mimicking the primary colon cancer (Fig. 3). Microscopically, the tumor was an adenocarcinoma with papillary and glandular architectures (Fig. 4). The tumor had infiltrated through the mucosa to the subserosa. Histology data from the previous ovarian cancer were reviewed and were found to be identical to histology data for the present colon tumor. Immunohistochemically, both the ovarian and the colon cancers were diffusely positive for cytokeratin 7 (CK7) and estrogen receptor (ER), but negative for CK20 and mucin 2 (MUC2). The histological and the immunohistochemical consistency of the two tumors demonstrated that the colon tumor was a metastatic papillary serous adenocarcinoma from the ovary. Two out of forty-six lymph nodes had microscopic evidence of a metastatic carcinoma. The patient was treated with six cycles of docetaxel and carboplatin. At the time of this report, her serum CA 125 levels had been in the normal range for 15 months, and there had been no evidence of recurrent or metastatic disease.


Colonic Metastasis Presenting as an Intraluminal Fungating Mass 8 Years After Surgery for Ovarian Cancer.

Kim JR, Kim BM, Kim YM, Lee WA, Namgung H - Ann Coloproctol (2015)

The colonic mucosa shows a huge fungating tumor simulating the primary colon cancer.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4644708&req=5

Figure 3: The colonic mucosa shows a huge fungating tumor simulating the primary colon cancer.
Mentions: The patient underwent a lower anterior resection with lymphnode dissection for the regional and the para-aortic lymph nodes. A 6-cm intraluminal mass was noted in the rectosigmoid junction with no evidence of a peritoneal seeding nodule in the pelvic and the abdominal cavities. Macroscopically, the mucosa revealed a huge fungating tumor mimicking the primary colon cancer (Fig. 3). Microscopically, the tumor was an adenocarcinoma with papillary and glandular architectures (Fig. 4). The tumor had infiltrated through the mucosa to the subserosa. Histology data from the previous ovarian cancer were reviewed and were found to be identical to histology data for the present colon tumor. Immunohistochemically, both the ovarian and the colon cancers were diffusely positive for cytokeratin 7 (CK7) and estrogen receptor (ER), but negative for CK20 and mucin 2 (MUC2). The histological and the immunohistochemical consistency of the two tumors demonstrated that the colon tumor was a metastatic papillary serous adenocarcinoma from the ovary. Two out of forty-six lymph nodes had microscopic evidence of a metastatic carcinoma. The patient was treated with six cycles of docetaxel and carboplatin. At the time of this report, her serum CA 125 levels had been in the normal range for 15 months, and there had been no evidence of recurrent or metastatic disease.

Bottom Line: We report a case of colonic metastasis from ovarian cancer presented as an intraluminal fungating mass mimicking primary colon cancer 8 years after surgery for ovarian cancer.A 70-year-old woman presented with constipation.A computed tomography scan showed a bulky intraluminal fungating mass in the rectosigmoid junction.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Dankook University College of Medicine, Cheonan, Korea.

ABSTRACT
We report a case of colonic metastasis from ovarian cancer presented as an intraluminal fungating mass mimicking primary colon cancer 8 years after surgery for ovarian cancer. A 70-year-old woman presented with constipation. She had undergone an extended total abdominal hysterectomy with bilateral salpingo-oophorectomy for an ovarian papillary serous cystadenocarcinoma 8 years earlier. Colonoscopy showed a large fungating mass 10 cm from the anal verge that was suspected to be colorectal cancer. A computed tomography scan showed a bulky intraluminal fungating mass in the rectosigmoid junction. After a lower anterior resection and a pathologic diagnosis, a diagnosis of a papillary serous adenocarcinoma due to metastasis from an ovarian tumor was made for this patient.

No MeSH data available.


Related in: MedlinePlus