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Risk Factors of a Pulmonary Thromboembolism After Colorectal Surgery.

Kim J, Bae BN, Jung HS, Park I, Cho H, Gwak G, Kim K, Kim HJ, Kim YD - Ann Coloproctol (2015)

Bottom Line: The postoperative patients with PTE were 14 (4.5%), and they were classified by sex, age, and stage as a 1:3 paired match to the control group.A multiple logistic regression was performed to identify which factors were associated with PTE.One patient was in stage I, 3 in stage II, 9 in stage III, and 1 in stage IV.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, Inje University Sanggye Paik Hospital, Seoul, Korea.

ABSTRACT

Purpose: Previous studies have revealed that predictors and risk factors of pulmonary thromboembolism (PTE) are malignancy, immobilization, diabetes, and obesity in the postoperative patients. However, in patients undergoing colorectal cancer, studies of PTE have not been enough. Thus, we investigated the risk factors of PTE related to colorectal surgery.

Methods: From January 2009 to October 2014, 312 patients received colorectal surgery without other organ resection. The postoperative patients with PTE were 14 (4.5%), and they were classified by sex, age, and stage as a 1:3 paired match to the control group. A multiple logistic regression was performed to identify which factors were associated with PTE.

Results: One patient was in stage I, 3 in stage II, 9 in stage III, and 1 in stage IV. In the binary logistic regression analysis, history of diabetes mellitus (odds ratio, 6.498; P = 0.031) and being overweight (odds ratio, 10.018; P = 0.014) were independent risk factors for PTE in patients undergoing colorectal cancer.

Conclusion: A history of diabetes mellitus and being overweight were independent risk factors of PTE after colorectal cancer.

No MeSH data available.


Related in: MedlinePlus

Flow chart of the study. PTE, pulmonary thromboembolism; DVT, deep vein thrombosis.
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Figure 1: Flow chart of the study. PTE, pulmonary thromboembolism; DVT, deep vein thrombosis.

Mentions: We evaluated 414 patients who had undergone colorectal cancer surgery between January 2009 and October 2014 at the Department of Surgery, Inje University Sanggye Paik Hospital, via a retrospective review of their medical records. Institutional Review Board approval was obtained from Inje University Sanggye Paik Hospital (IRB No. 2015-05-18). After patients with a history of synchronous organ resection at other metastatic sites and deep vein thrombosis (DVT) had been excluded, a total of 312 patients with colorectal cancer were included for our retrospective analysis. PTE was postoperatively diagnosed by using chest computed tomography (CT) before initiation of chemotherapy or regular clinical laboratory tests. Patients underwent routine chest and abdominal CT scans every 3 months after the surgical procedure for the first year, then every 6 months for 2 years, and every year thereafter. For recurrent colorectal cancer, chest CT scans were performed prior to chemotherapy. Of the 312 patients screened, a total of 14 patients (4.5%) were finally diagnosed with PTE, and these patients underwent a chest CT scan every 3 months (Fig. 1).


Risk Factors of a Pulmonary Thromboembolism After Colorectal Surgery.

Kim J, Bae BN, Jung HS, Park I, Cho H, Gwak G, Kim K, Kim HJ, Kim YD - Ann Coloproctol (2015)

Flow chart of the study. PTE, pulmonary thromboembolism; DVT, deep vein thrombosis.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4644706&req=5

Figure 1: Flow chart of the study. PTE, pulmonary thromboembolism; DVT, deep vein thrombosis.
Mentions: We evaluated 414 patients who had undergone colorectal cancer surgery between January 2009 and October 2014 at the Department of Surgery, Inje University Sanggye Paik Hospital, via a retrospective review of their medical records. Institutional Review Board approval was obtained from Inje University Sanggye Paik Hospital (IRB No. 2015-05-18). After patients with a history of synchronous organ resection at other metastatic sites and deep vein thrombosis (DVT) had been excluded, a total of 312 patients with colorectal cancer were included for our retrospective analysis. PTE was postoperatively diagnosed by using chest computed tomography (CT) before initiation of chemotherapy or regular clinical laboratory tests. Patients underwent routine chest and abdominal CT scans every 3 months after the surgical procedure for the first year, then every 6 months for 2 years, and every year thereafter. For recurrent colorectal cancer, chest CT scans were performed prior to chemotherapy. Of the 312 patients screened, a total of 14 patients (4.5%) were finally diagnosed with PTE, and these patients underwent a chest CT scan every 3 months (Fig. 1).

Bottom Line: The postoperative patients with PTE were 14 (4.5%), and they were classified by sex, age, and stage as a 1:3 paired match to the control group.A multiple logistic regression was performed to identify which factors were associated with PTE.One patient was in stage I, 3 in stage II, 9 in stage III, and 1 in stage IV.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, Inje University Sanggye Paik Hospital, Seoul, Korea.

ABSTRACT

Purpose: Previous studies have revealed that predictors and risk factors of pulmonary thromboembolism (PTE) are malignancy, immobilization, diabetes, and obesity in the postoperative patients. However, in patients undergoing colorectal cancer, studies of PTE have not been enough. Thus, we investigated the risk factors of PTE related to colorectal surgery.

Methods: From January 2009 to October 2014, 312 patients received colorectal surgery without other organ resection. The postoperative patients with PTE were 14 (4.5%), and they were classified by sex, age, and stage as a 1:3 paired match to the control group. A multiple logistic regression was performed to identify which factors were associated with PTE.

Results: One patient was in stage I, 3 in stage II, 9 in stage III, and 1 in stage IV. In the binary logistic regression analysis, history of diabetes mellitus (odds ratio, 6.498; P = 0.031) and being overweight (odds ratio, 10.018; P = 0.014) were independent risk factors for PTE in patients undergoing colorectal cancer.

Conclusion: A history of diabetes mellitus and being overweight were independent risk factors of PTE after colorectal cancer.

No MeSH data available.


Related in: MedlinePlus