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Blastomycosis in northwestern Ontario, 2004 to 2014.

Dalcin D, Ahmed SZ - Can J Infect Dis Med Microbiol (2015 Sep-Oct)

Bottom Line: Aboriginals were observed to be disproportionately represented in the patient population.Of the patients whose smoking status was known, 71.4% had a history of smoking. 59.4% of patients had underlying comorbidities and a higher comorbidity rate was observed among Aboriginal patients.Abstract available from the publisher.

View Article: PubMed Central - PubMed

Affiliation: Northern Ontario School of Medicine, Thunder Bay Regional Health Sciences Centre, Thunder Bay, Ontario.

ABSTRACT
Blastomycosis is an invasive fungal disease caused by Blastomyces dermatitidis and the recently discovered Blastomyces gilchristii. The medical charts of 64 patients with confirmed cases of blastomycosis in northwestern Ontario during a 10-year period (2004 to 2014) were retrospectively reviewed. The number of patients diagnosed with blastomycosis in Ontario was observed to have increased substantially compared with before 1990, when blastomycosis was removed from the list of reportable diseases. Aboriginals were observed to be disproportionately represented in the patient population. Of the patients whose smoking status was known, 71.4% had a history of smoking. 59.4% of patients had underlying comorbidities and a higher comorbidity rate was observed among Aboriginal patients. The case-fatality rate from direct complications of blastomycosis disease was calculated to be 20.3%; this case-fatality rate is the highest ever to be reported in Canada and more than double that of previously published Canadian studies. The clinical characteristics of 64 patients diagnosed with blastomycosis are summarized.

No MeSH data available.


Related in: MedlinePlus

Number (No) of patients presenting with blastomycosis at the Thunder Bay Regional Health Services Centre (TBRHSC, Thunder Bay, Ontario) according to year of diagnosis from February 1, 2004 to January 31, 2014. The number of cases of blastomycosis diagnosed in Ontario has substantially increased since 1990, when a mean of two cases were diagnosed per year. The mean number of cases diagnosed at the TBRHSC was 6.4 per year
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f1-cjidmm-26-259: Number (No) of patients presenting with blastomycosis at the Thunder Bay Regional Health Services Centre (TBRHSC, Thunder Bay, Ontario) according to year of diagnosis from February 1, 2004 to January 31, 2014. The number of cases of blastomycosis diagnosed in Ontario has substantially increased since 1990, when a mean of two cases were diagnosed per year. The mean number of cases diagnosed at the TBRHSC was 6.4 per year

Mentions: Due to incomplete information from patients transferred to the TBRHSC from other facilities, the month and year of diagnosis was available for only 60 patients. Cases of blastomycosis were diagnosed in all months of the year; however, a slightly higher proportion of patients were diagnosed between October and March (60.0% of patients). The number of cases diagnosed per year ranged from two to 11 cases, with a mean of 6.4 cases per year (Figure 1).


Blastomycosis in northwestern Ontario, 2004 to 2014.

Dalcin D, Ahmed SZ - Can J Infect Dis Med Microbiol (2015 Sep-Oct)

Number (No) of patients presenting with blastomycosis at the Thunder Bay Regional Health Services Centre (TBRHSC, Thunder Bay, Ontario) according to year of diagnosis from February 1, 2004 to January 31, 2014. The number of cases of blastomycosis diagnosed in Ontario has substantially increased since 1990, when a mean of two cases were diagnosed per year. The mean number of cases diagnosed at the TBRHSC was 6.4 per year
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4644009&req=5

f1-cjidmm-26-259: Number (No) of patients presenting with blastomycosis at the Thunder Bay Regional Health Services Centre (TBRHSC, Thunder Bay, Ontario) according to year of diagnosis from February 1, 2004 to January 31, 2014. The number of cases of blastomycosis diagnosed in Ontario has substantially increased since 1990, when a mean of two cases were diagnosed per year. The mean number of cases diagnosed at the TBRHSC was 6.4 per year
Mentions: Due to incomplete information from patients transferred to the TBRHSC from other facilities, the month and year of diagnosis was available for only 60 patients. Cases of blastomycosis were diagnosed in all months of the year; however, a slightly higher proportion of patients were diagnosed between October and March (60.0% of patients). The number of cases diagnosed per year ranged from two to 11 cases, with a mean of 6.4 cases per year (Figure 1).

Bottom Line: Aboriginals were observed to be disproportionately represented in the patient population.Of the patients whose smoking status was known, 71.4% had a history of smoking. 59.4% of patients had underlying comorbidities and a higher comorbidity rate was observed among Aboriginal patients.Abstract available from the publisher.

View Article: PubMed Central - PubMed

Affiliation: Northern Ontario School of Medicine, Thunder Bay Regional Health Sciences Centre, Thunder Bay, Ontario.

ABSTRACT
Blastomycosis is an invasive fungal disease caused by Blastomyces dermatitidis and the recently discovered Blastomyces gilchristii. The medical charts of 64 patients with confirmed cases of blastomycosis in northwestern Ontario during a 10-year period (2004 to 2014) were retrospectively reviewed. The number of patients diagnosed with blastomycosis in Ontario was observed to have increased substantially compared with before 1990, when blastomycosis was removed from the list of reportable diseases. Aboriginals were observed to be disproportionately represented in the patient population. Of the patients whose smoking status was known, 71.4% had a history of smoking. 59.4% of patients had underlying comorbidities and a higher comorbidity rate was observed among Aboriginal patients. The case-fatality rate from direct complications of blastomycosis disease was calculated to be 20.3%; this case-fatality rate is the highest ever to be reported in Canada and more than double that of previously published Canadian studies. The clinical characteristics of 64 patients diagnosed with blastomycosis are summarized.

No MeSH data available.


Related in: MedlinePlus