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Brachytherapy in the treatment of lung cancer - a valuable solution.

Skowronek J - J Contemp Brachytherapy (2015)

Bottom Line: Efforts to relieve this obstructive process are worthwhile, because patients may experience improved quality of their life (QoL).This option is fast, inexpensive, and easy to perform on an outpatient basis.Clinical indications, different techniques, results, and complications are presented in this work.

View Article: PubMed Central - PubMed

Affiliation: Brachytherapy Department, Greater Poland Cancer Center ; Electroradiology Department, Poznan University of Medical Sciences, Poznan, Poland.

ABSTRACT
The majority of patients with lung cancer are diagnosed with clinically advanced disease. Many of these patients have a short life expectancy and are treated with palliative aim. Because of uncontrolled local or recurrent disease, patients may have significant symptoms such as: cough, dyspnea, hemoptysis, obstructive pneumonia, or atelectasis. Brachytherapy is one of the most efficient methods in overcoming difficulties in breathing that is caused by endobronchial obstruction in palliative treatment of bronchus cancer. Efforts to relieve this obstructive process are worthwhile, because patients may experience improved quality of their life (QoL). Brachytherapy plays a limited but specific role in definitive treatment with curative intent in selected cases of early endobronchial disease as well as in the postoperative treatment of small residual peribronchial disease. Depending on the location of the lesion, in some cases brachytherapy is a treatment of choice. This option is fast, inexpensive, and easy to perform on an outpatient basis. Clinical indications, different techniques, results, and complications are presented in this work.

No MeSH data available.


Related in: MedlinePlus

Lung metastasis of colorectal carcinoma treated with a singlebrachytherapy catheter. The inner isodose represents 20 Gy. Note thesteep gradient with the outer isodose, illustrating a dose of 3 Gy[46]
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Figure 0010: Lung metastasis of colorectal carcinoma treated with a singlebrachytherapy catheter. The inner isodose represents 20 Gy. Note thesteep gradient with the outer isodose, illustrating a dose of 3 Gy[46]

Mentions: An alternative for permanent brachytherapy could be interstitialbrachytherapy with the use of HDR sources. Sometimes the costs are the mostimportant reason for choosing this technique. If permanent implants are notavailable, in one procedure elastic applicators (using steel needles first)are inserted into tumor tissue. After preparing a treatment plan, a patientis connected to the HDR unit and irradiated. High-dose-rate brachytherapy isused in tumors smaller than 2 cm in diameter. One fraction of 10-20 Gy wasused so far (Figure 10). After notcomplete tumor excision, elastic applicators can be fixed in tumor bed.Three to seven days after surgery HDR-BT is performed, 3-4 fractions of 4-5Gy are used (one fraction daily) [40, 41, 45, 46].


Brachytherapy in the treatment of lung cancer - a valuable solution.

Skowronek J - J Contemp Brachytherapy (2015)

Lung metastasis of colorectal carcinoma treated with a singlebrachytherapy catheter. The inner isodose represents 20 Gy. Note thesteep gradient with the outer isodose, illustrating a dose of 3 Gy[46]
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4643732&req=5

Figure 0010: Lung metastasis of colorectal carcinoma treated with a singlebrachytherapy catheter. The inner isodose represents 20 Gy. Note thesteep gradient with the outer isodose, illustrating a dose of 3 Gy[46]
Mentions: An alternative for permanent brachytherapy could be interstitialbrachytherapy with the use of HDR sources. Sometimes the costs are the mostimportant reason for choosing this technique. If permanent implants are notavailable, in one procedure elastic applicators (using steel needles first)are inserted into tumor tissue. After preparing a treatment plan, a patientis connected to the HDR unit and irradiated. High-dose-rate brachytherapy isused in tumors smaller than 2 cm in diameter. One fraction of 10-20 Gy wasused so far (Figure 10). After notcomplete tumor excision, elastic applicators can be fixed in tumor bed.Three to seven days after surgery HDR-BT is performed, 3-4 fractions of 4-5Gy are used (one fraction daily) [40, 41, 45, 46].

Bottom Line: Efforts to relieve this obstructive process are worthwhile, because patients may experience improved quality of their life (QoL).This option is fast, inexpensive, and easy to perform on an outpatient basis.Clinical indications, different techniques, results, and complications are presented in this work.

View Article: PubMed Central - PubMed

Affiliation: Brachytherapy Department, Greater Poland Cancer Center ; Electroradiology Department, Poznan University of Medical Sciences, Poznan, Poland.

ABSTRACT
The majority of patients with lung cancer are diagnosed with clinically advanced disease. Many of these patients have a short life expectancy and are treated with palliative aim. Because of uncontrolled local or recurrent disease, patients may have significant symptoms such as: cough, dyspnea, hemoptysis, obstructive pneumonia, or atelectasis. Brachytherapy is one of the most efficient methods in overcoming difficulties in breathing that is caused by endobronchial obstruction in palliative treatment of bronchus cancer. Efforts to relieve this obstructive process are worthwhile, because patients may experience improved quality of their life (QoL). Brachytherapy plays a limited but specific role in definitive treatment with curative intent in selected cases of early endobronchial disease as well as in the postoperative treatment of small residual peribronchial disease. Depending on the location of the lesion, in some cases brachytherapy is a treatment of choice. This option is fast, inexpensive, and easy to perform on an outpatient basis. Clinical indications, different techniques, results, and complications are presented in this work.

No MeSH data available.


Related in: MedlinePlus