Asymmetrical white matter networks for attending to global versus local features.
Bottom Line: We found (i) that reproduction of local features in figure copying was supported by a neural network confined to the left hemisphere, consisting of cortical loci within parietal, occipital and insular lobes and interconnected by the inferior-fronto-occipital fasciculus (IFOF), and (ii) that global feature processing was associated with a right hemisphere network interconnected by the third branch of the superior longitudinal fasciculus and the long segment of the perisylvian network.The data support the argument that asymmetrical white matter disconnections within long-range association pathways predict poor complex figure drawing resulting from deficits in hierarchical representation.We conclude that hemispheric asymmetries in attending to local versus global features exist on the level of both cortical loci and the supporting white matter pathways.
Affiliation: Department of Experimental Psychology, University of Oxford, Oxford, UK. Electronic address: firstname.lastname@example.org.Show MeSH
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Mentions: The BCoS complex figure consists of a rectangular box divided into 3 global rectangles. Within each of these rectangles are various local features, such as dots, diagonal lines and arrows (see Fig. 1A and Humphreys et al., 2012 for details). Two criteria are used to determine whether patient could be tested on the task: (1) whether the patient was able to hold a pen and (2) whether the patient could make fluent marks/lines on paper. The complex figure was presented to the patient in the top half of an A4 page and the patient was asked to draw an exact copy of the image underneath the original. Patients were given a maximum of 5 min to complete the task. Following the BCoS manual, once the figure has been copied, performance was scored according to whether or not the visual elements were present (1 point each), the correct shapes were represented (1 point each), and whether the elements were assigned their correct position (1 point each), with the maximum achievable score being 47 points (see Fig. 1A for full details of scoring).
Affiliation: Department of Experimental Psychology, University of Oxford, Oxford, UK. Electronic address: email@example.com.