Limits...
Design and Evaluation of a Fully Implantable Control Unit for Blood Pumps.

Unthan K, Gräf F, Laumen M, Finocchiaro T, Sommer C, Lanmüller H, Steinseifer U - Biomed Res Int (2015)

Bottom Line: As the number of donor hearts is limited while more and more patients suffer from end stage biventricular heart failure, Total Artificial Hearts become a promising alternative to conventional treatment.In validation tests, the control unit demonstrated a stable operation on TET and battery supply and a safe switching from one supply to the other.The overall mean efficiency is 14% on TET and 22% on battery supply.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, Helmholtz Institute, RWTH Aachen University, 52074 Aachen, Germany.

ABSTRACT
As the number of donor hearts is limited while more and more patients suffer from end stage biventricular heart failure, Total Artificial Hearts become a promising alternative to conventional treatment. While pneumatic devices sufficiently supply the patients with blood flow, the patient's quality of life is limited by the percutaneous pressure lines and the size of the external control unit. This paper describes the development of the control unit of the ReinHeart, a fully implantable Total Artificial Heart. General requirements for any implantable control unit are defined from a technical and medical point of view: necessity of a Transcutaneous Energy Transmission, autonomous operation, safety, geometry, and efficiency. Based on the requirements, a prototype is designed; it incorporates a LiFePo4 battery pack with charger, a rectifier for transcutaneous energy transmission, the motor's driver electronics, and a microcontroller which monitors and controls all functions. In validation tests, the control unit demonstrated a stable operation on TET and battery supply and a safe switching from one supply to the other. The overall mean efficiency is 14% on TET and 22% on battery supply. The control unit is suitable for chronic animal trials of the ReinHeart.

No MeSH data available.


Related in: MedlinePlus

Assembly of the complete TAH system [5].
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Related In: Results  -  Collection


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fig2: Assembly of the complete TAH system [5].

Mentions: Anatomical fitting studies, both virtual and cadaver studies, were conducted to determine the optimal size and location of the pump unit in a former study [11]. As a result, the TAH motor unit and ventricles have a diameter of 85 mm and a height of 90 mm. Because the space of the native heart is taken up completely by the pump unit, the electronics must be placed in a separate casing, which is located in the abdomen. To minimize the invasive approach, the electronics and the internal batteries must fit in the same casing. The resulting device configuration is displayed in Figure 2.


Design and Evaluation of a Fully Implantable Control Unit for Blood Pumps.

Unthan K, Gräf F, Laumen M, Finocchiaro T, Sommer C, Lanmüller H, Steinseifer U - Biomed Res Int (2015)

Assembly of the complete TAH system [5].
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4637009&req=5

fig2: Assembly of the complete TAH system [5].
Mentions: Anatomical fitting studies, both virtual and cadaver studies, were conducted to determine the optimal size and location of the pump unit in a former study [11]. As a result, the TAH motor unit and ventricles have a diameter of 85 mm and a height of 90 mm. Because the space of the native heart is taken up completely by the pump unit, the electronics must be placed in a separate casing, which is located in the abdomen. To minimize the invasive approach, the electronics and the internal batteries must fit in the same casing. The resulting device configuration is displayed in Figure 2.

Bottom Line: As the number of donor hearts is limited while more and more patients suffer from end stage biventricular heart failure, Total Artificial Hearts become a promising alternative to conventional treatment.In validation tests, the control unit demonstrated a stable operation on TET and battery supply and a safe switching from one supply to the other.The overall mean efficiency is 14% on TET and 22% on battery supply.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, Helmholtz Institute, RWTH Aachen University, 52074 Aachen, Germany.

ABSTRACT
As the number of donor hearts is limited while more and more patients suffer from end stage biventricular heart failure, Total Artificial Hearts become a promising alternative to conventional treatment. While pneumatic devices sufficiently supply the patients with blood flow, the patient's quality of life is limited by the percutaneous pressure lines and the size of the external control unit. This paper describes the development of the control unit of the ReinHeart, a fully implantable Total Artificial Heart. General requirements for any implantable control unit are defined from a technical and medical point of view: necessity of a Transcutaneous Energy Transmission, autonomous operation, safety, geometry, and efficiency. Based on the requirements, a prototype is designed; it incorporates a LiFePo4 battery pack with charger, a rectifier for transcutaneous energy transmission, the motor's driver electronics, and a microcontroller which monitors and controls all functions. In validation tests, the control unit demonstrated a stable operation on TET and battery supply and a safe switching from one supply to the other. The overall mean efficiency is 14% on TET and 22% on battery supply. The control unit is suitable for chronic animal trials of the ReinHeart.

No MeSH data available.


Related in: MedlinePlus