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Independent prognostic value of left atrial function by two-dimensional speckle tracking imaging in patients with non -ST-segment-elevation acute myocardial infarction.

Shao C, Zhu J, Chen J, Xu W - BMC Cardiovasc Disord (2015)

Bottom Line: The final study population consisted of 51 individuals (43 males and 8 females; mean age of 62.9 ± 11.1 years) and a 12 ± 3 months follow-up was performed.A total of 22 combined cardiovascular events(20 patients) occurred.With the use of Univariable Cox regression, all parameters were evaluated in the prediction of cardiac events, ischemic events, and/or cardiac death.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiology, The Second Affiliated Hospital of Soochow University, Sanxiang Street 1055, Suzhou, China. aquariusheart@hotmail.com.

ABSTRACT

Background: The objective of this study is to evaluate left atrial(LA) function and its prognostic value by two-dimensional speckle tracking echocardiography (STE) in patients with non-ST-segment-elevation acute myocardial infarction (NSTEAMI).

Methods: Global longitudinal LA S/SR data obtained by 2D speckle imaging with automated software (Echo PAC, GE Medical).

Results: Clinical variables and angiographic, echocardiographic, and STE parameters were studied in 65 patients with NSTEAMI (51 males and 14 females; mean age of 60.7 ± 9.8 years) who underwent elective PCI. The final study population consisted of 51 individuals (43 males and 8 females; mean age of 62.9 ± 11.1 years) and a 12 ± 3 months follow-up was performed. A total of 22 combined cardiovascular events(20 patients) occurred. With the use of Univariable Cox regression, all parameters were evaluated in the prediction of cardiac events, ischemic events, and/or cardiac death. According to ROC analysis, baseline mean global left atrial SRs (ROC area 0.82, p = 0.001) and baseline mean global left atrial SRe (ROC area 0.68, p = 0.036) were the only predictive variables.

Conclusions: In patients with NSTEAMI, we found that the novel global strain parameter of left atrial function is a valuable predictor of combined cardiovascular events over conventional echocardiography and may therefore be an important clinical tool for risk stratification in the acute phase of NSTEAMI.

No MeSH data available.


Related in: MedlinePlus

Receiver operator characteristic analyses of echocardiography parameters to predict Combined Cardiovascular Events with optimal cut-offs in patients with NSTEAMI
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Fig3: Receiver operator characteristic analyses of echocardiography parameters to predict Combined Cardiovascular Events with optimal cut-offs in patients with NSTEAMI

Mentions: In accordance to the ROC analysis, baseline mean GLSRs (ROC area 0.82, p = 0.001) and baseline mean GLSRe (ROC area 0.68, p = 0.036) displayed a better prognostic value in predicting cardiac events than LAPEF (ROC area 0.64, p = 0.094) and LA total EF (ROC area 0.39, p = 0.174). The “optimal” cut off values of baseline mean GLSRs and baseline mean Glare for cardiac events were 1.62 (s−1) and −1.16 (s−1), respectively (Table 6 and Fig. 3).Table 6


Independent prognostic value of left atrial function by two-dimensional speckle tracking imaging in patients with non -ST-segment-elevation acute myocardial infarction.

Shao C, Zhu J, Chen J, Xu W - BMC Cardiovasc Disord (2015)

Receiver operator characteristic analyses of echocardiography parameters to predict Combined Cardiovascular Events with optimal cut-offs in patients with NSTEAMI
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4634898&req=5

Fig3: Receiver operator characteristic analyses of echocardiography parameters to predict Combined Cardiovascular Events with optimal cut-offs in patients with NSTEAMI
Mentions: In accordance to the ROC analysis, baseline mean GLSRs (ROC area 0.82, p = 0.001) and baseline mean GLSRe (ROC area 0.68, p = 0.036) displayed a better prognostic value in predicting cardiac events than LAPEF (ROC area 0.64, p = 0.094) and LA total EF (ROC area 0.39, p = 0.174). The “optimal” cut off values of baseline mean GLSRs and baseline mean Glare for cardiac events were 1.62 (s−1) and −1.16 (s−1), respectively (Table 6 and Fig. 3).Table 6

Bottom Line: The final study population consisted of 51 individuals (43 males and 8 females; mean age of 62.9 ± 11.1 years) and a 12 ± 3 months follow-up was performed.A total of 22 combined cardiovascular events(20 patients) occurred.With the use of Univariable Cox regression, all parameters were evaluated in the prediction of cardiac events, ischemic events, and/or cardiac death.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiology, The Second Affiliated Hospital of Soochow University, Sanxiang Street 1055, Suzhou, China. aquariusheart@hotmail.com.

ABSTRACT

Background: The objective of this study is to evaluate left atrial(LA) function and its prognostic value by two-dimensional speckle tracking echocardiography (STE) in patients with non-ST-segment-elevation acute myocardial infarction (NSTEAMI).

Methods: Global longitudinal LA S/SR data obtained by 2D speckle imaging with automated software (Echo PAC, GE Medical).

Results: Clinical variables and angiographic, echocardiographic, and STE parameters were studied in 65 patients with NSTEAMI (51 males and 14 females; mean age of 60.7 ± 9.8 years) who underwent elective PCI. The final study population consisted of 51 individuals (43 males and 8 females; mean age of 62.9 ± 11.1 years) and a 12 ± 3 months follow-up was performed. A total of 22 combined cardiovascular events(20 patients) occurred. With the use of Univariable Cox regression, all parameters were evaluated in the prediction of cardiac events, ischemic events, and/or cardiac death. According to ROC analysis, baseline mean global left atrial SRs (ROC area 0.82, p = 0.001) and baseline mean global left atrial SRe (ROC area 0.68, p = 0.036) were the only predictive variables.

Conclusions: In patients with NSTEAMI, we found that the novel global strain parameter of left atrial function is a valuable predictor of combined cardiovascular events over conventional echocardiography and may therefore be an important clinical tool for risk stratification in the acute phase of NSTEAMI.

No MeSH data available.


Related in: MedlinePlus