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Parapharyngeal Angiofibroma: A Case Report.

Lee BH - Iran J Radiol (2015)

Bottom Line: Nasopharyngeal angiofibroma is a relatively uncommon vascular tumor affecting adolescent males and it characteristically originates in the posterior lateral wall of the nasopharynx.Primary extra-nasopharyngeal angiofibroma is very rare.Here, I present a case of angiofibroma of the parapharyngeal space in a 53-year-old woman with CT and sonographic findings.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Ilsan Paik Hospital, Inje University School of Medicine, Gyeonggi-do, South Korea.

ABSTRACT
Nasopharyngeal angiofibroma is a relatively uncommon vascular tumor affecting adolescent males and it characteristically originates in the posterior lateral wall of the nasopharynx. Primary extra-nasopharyngeal angiofibroma is very rare. Here, I present a case of angiofibroma of the parapharyngeal space in a 53-year-old woman with CT and sonographic findings.

No MeSH data available.


Related in: MedlinePlus

A, Microscopic examination reveals intricate mixture of stellate and staghorn blood vessels with variable shapes with fibrous and edematous stroma (H & E ×100). B, CD34 immunohistochemistry shows well-defined variable sized vessels (×100).
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fig19202: A, Microscopic examination reveals intricate mixture of stellate and staghorn blood vessels with variable shapes with fibrous and edematous stroma (H & E ×100). B, CD34 immunohistochemistry shows well-defined variable sized vessels (×100).

Mentions: A 53-year-old woman presented with a diffuse anterior neck swelling of one-month duration. The patient had not undergone any previous surgery. Physical examination revealed no evidence of palpable cervical lymphadenopathy. Ultrasonography (US) showed diffuse goiter with multiple thyroid nodules. A homogeneous and hypoechoic solid mass, adjacent to the upper margin of the right submandibular gland with focal flow signals on color Doppler sonography within the mass was detected (Figure 1). A computed tomography (CT) scan revealed a circumscribed mass, hypodense to the masseter muscle and hyperdense to the parotid gland in the right parapharyngeal space (Figure 2 A-C). After intravenous contrast administration, the mass, 1.7 × 1.7 × 1.6 cm in size, demonstrated homogeneous enhancement without infiltration to the adjacent muscle. At that time, radiological differential diagnoses included salivary gland origin tumor or paraganglioma or neurogenic tumors. Enlargement of the bilateral thyroid lobes with multiple non-enhancing hypodense and calcified thyroid nodules was also noted. Under general anesthesia, this mass was excised surgically. The histological diagnosis was an angiofibroma without evidence of malignancy (Figure 3). After surgery, the patient revealed an uneventful postoperative course. At the three-year follow-up examination, the patient remained free of any recurrence.


Parapharyngeal Angiofibroma: A Case Report.

Lee BH - Iran J Radiol (2015)

A, Microscopic examination reveals intricate mixture of stellate and staghorn blood vessels with variable shapes with fibrous and edematous stroma (H & E ×100). B, CD34 immunohistochemistry shows well-defined variable sized vessels (×100).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4632154&req=5

fig19202: A, Microscopic examination reveals intricate mixture of stellate and staghorn blood vessels with variable shapes with fibrous and edematous stroma (H & E ×100). B, CD34 immunohistochemistry shows well-defined variable sized vessels (×100).
Mentions: A 53-year-old woman presented with a diffuse anterior neck swelling of one-month duration. The patient had not undergone any previous surgery. Physical examination revealed no evidence of palpable cervical lymphadenopathy. Ultrasonography (US) showed diffuse goiter with multiple thyroid nodules. A homogeneous and hypoechoic solid mass, adjacent to the upper margin of the right submandibular gland with focal flow signals on color Doppler sonography within the mass was detected (Figure 1). A computed tomography (CT) scan revealed a circumscribed mass, hypodense to the masseter muscle and hyperdense to the parotid gland in the right parapharyngeal space (Figure 2 A-C). After intravenous contrast administration, the mass, 1.7 × 1.7 × 1.6 cm in size, demonstrated homogeneous enhancement without infiltration to the adjacent muscle. At that time, radiological differential diagnoses included salivary gland origin tumor or paraganglioma or neurogenic tumors. Enlargement of the bilateral thyroid lobes with multiple non-enhancing hypodense and calcified thyroid nodules was also noted. Under general anesthesia, this mass was excised surgically. The histological diagnosis was an angiofibroma without evidence of malignancy (Figure 3). After surgery, the patient revealed an uneventful postoperative course. At the three-year follow-up examination, the patient remained free of any recurrence.

Bottom Line: Nasopharyngeal angiofibroma is a relatively uncommon vascular tumor affecting adolescent males and it characteristically originates in the posterior lateral wall of the nasopharynx.Primary extra-nasopharyngeal angiofibroma is very rare.Here, I present a case of angiofibroma of the parapharyngeal space in a 53-year-old woman with CT and sonographic findings.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Ilsan Paik Hospital, Inje University School of Medicine, Gyeonggi-do, South Korea.

ABSTRACT
Nasopharyngeal angiofibroma is a relatively uncommon vascular tumor affecting adolescent males and it characteristically originates in the posterior lateral wall of the nasopharynx. Primary extra-nasopharyngeal angiofibroma is very rare. Here, I present a case of angiofibroma of the parapharyngeal space in a 53-year-old woman with CT and sonographic findings.

No MeSH data available.


Related in: MedlinePlus