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Linkage Mapping Reveals Strong Chiasma Interference in Sockeye Salmon: Implications for Interpreting Genomic Data.

Limborg MT, Waples RK, Allendorf FW, Seeb JE - G3 (Bethesda) (2015)

Bottom Line: Salmonid fishes provide a valuable system for studying the effects of recombination in nonmodel species.We also estimate the strength of interference across each chromosome; results reveal strong interference and crossovers are mostly limited to one per arm.We discuss the relevance of these findings for both mapping and population genomic studies.

View Article: PubMed Central - PubMed

Affiliation: School of Aquatic and Fishery Sciences, University of Washington, Seattle, Washington 98195 National Institute of Aquatic Resources, Technical University of Denmark, Vejlsøvej 39, Silkeborg, Denmark morten.limborg@gmail.com.

No MeSH data available.


Genome-wide distribution of y values estimated for all nonduplicated loci in the gynogenetic diploid family. Loci with values near zero are expected to be proximal to centromeres, and loci with higher values are expected to be more distally located. Values of y above 0.67 are only expected with the occurrence of positive crossover interference.
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fig4: Genome-wide distribution of y values estimated for all nonduplicated loci in the gynogenetic diploid family. Loci with values near zero are expected to be proximal to centromeres, and loci with higher values are expected to be more distally located. Values of y above 0.67 are only expected with the occurrence of positive crossover interference.

Mentions: The number of observed recombination events for each arm reveals a pattern of strong, but incomplete, interference. Among haploid progeny, only 64 of 1902 (3.4%) observations showed two crossovers within a single arm (Table 2). Similarly, we observed 178 of 3777 (4.7%) arms with more than one crossover among the diploid progeny (Table 2). Further evidence for interference was revealed by a high fraction of distal loci with y values above 0.67 (Figure 4).


Linkage Mapping Reveals Strong Chiasma Interference in Sockeye Salmon: Implications for Interpreting Genomic Data.

Limborg MT, Waples RK, Allendorf FW, Seeb JE - G3 (Bethesda) (2015)

Genome-wide distribution of y values estimated for all nonduplicated loci in the gynogenetic diploid family. Loci with values near zero are expected to be proximal to centromeres, and loci with higher values are expected to be more distally located. Values of y above 0.67 are only expected with the occurrence of positive crossover interference.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4632065&req=5

fig4: Genome-wide distribution of y values estimated for all nonduplicated loci in the gynogenetic diploid family. Loci with values near zero are expected to be proximal to centromeres, and loci with higher values are expected to be more distally located. Values of y above 0.67 are only expected with the occurrence of positive crossover interference.
Mentions: The number of observed recombination events for each arm reveals a pattern of strong, but incomplete, interference. Among haploid progeny, only 64 of 1902 (3.4%) observations showed two crossovers within a single arm (Table 2). Similarly, we observed 178 of 3777 (4.7%) arms with more than one crossover among the diploid progeny (Table 2). Further evidence for interference was revealed by a high fraction of distal loci with y values above 0.67 (Figure 4).

Bottom Line: Salmonid fishes provide a valuable system for studying the effects of recombination in nonmodel species.We also estimate the strength of interference across each chromosome; results reveal strong interference and crossovers are mostly limited to one per arm.We discuss the relevance of these findings for both mapping and population genomic studies.

View Article: PubMed Central - PubMed

Affiliation: School of Aquatic and Fishery Sciences, University of Washington, Seattle, Washington 98195 National Institute of Aquatic Resources, Technical University of Denmark, Vejlsøvej 39, Silkeborg, Denmark morten.limborg@gmail.com.

No MeSH data available.