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Histoid leprosy: a rare exuberant case.

Andrade PJ, Messias Sdos S, Ferreira PC, Sales AM, Machado Ade M, Nery JA - An Bras Dermatol (2015)

Bottom Line: AbstractLeprosy is a neglected disease.We point up the need of recognizing the unusual clinical presentations of the disease in order to make early diagnosis and proper treatment possible, and break the transmission chain.The authors report a rare type of multibacillary leprosy: histoid leprosy and present images of numerous well-circumscribed indurated papules and nodules distributed throughout the entire body.

View Article: PubMed Central - PubMed

Affiliation: Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil.

ABSTRACT
AbstractLeprosy is a neglected disease. We point up the need of recognizing the unusual clinical presentations of the disease in order to make early diagnosis and proper treatment possible, and break the transmission chain. The authors report a rare type of multibacillary leprosy: histoid leprosy and present images of numerous well-circumscribed indurated papules and nodules distributed throughout the entire body.

No MeSH data available.


Related in: MedlinePlus

Presence of several papular-nodular, ulcerated, crusted lesions on the left forearmand left hand
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f03: Presence of several papular-nodular, ulcerated, crusted lesions on the left forearmand left hand

Mentions: Histoid leprosy, an uncommon form of multibacillary leprosy, was first described by Wade in1963.1 Clinically, it ischaracterized by the presence of numerous indurated, infiltrated, keloid, skin-colored orerythematous papules and nodules with no preferred location (Figures 1,2 and 3).2,3,4 Skin histologyreveals an abundant amount of bacilli and elongated or fusiform histiocytes, similar toneurofibroma.3,5,6 This form is rarein treatment-naïve patients. The literature discusses causal factors, such as drugresistance to dapsone or mutation of strains of Mycobacteriumleprae..2,7 The differential diagnosis should be made with sarcoidosis,dermatofibroma, cutaneous metastasis and angiosarcoma.8


Histoid leprosy: a rare exuberant case.

Andrade PJ, Messias Sdos S, Ferreira PC, Sales AM, Machado Ade M, Nery JA - An Bras Dermatol (2015)

Presence of several papular-nodular, ulcerated, crusted lesions on the left forearmand left hand
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4631246&req=5

f03: Presence of several papular-nodular, ulcerated, crusted lesions on the left forearmand left hand
Mentions: Histoid leprosy, an uncommon form of multibacillary leprosy, was first described by Wade in1963.1 Clinically, it ischaracterized by the presence of numerous indurated, infiltrated, keloid, skin-colored orerythematous papules and nodules with no preferred location (Figures 1,2 and 3).2,3,4 Skin histologyreveals an abundant amount of bacilli and elongated or fusiform histiocytes, similar toneurofibroma.3,5,6 This form is rarein treatment-naïve patients. The literature discusses causal factors, such as drugresistance to dapsone or mutation of strains of Mycobacteriumleprae..2,7 The differential diagnosis should be made with sarcoidosis,dermatofibroma, cutaneous metastasis and angiosarcoma.8

Bottom Line: AbstractLeprosy is a neglected disease.We point up the need of recognizing the unusual clinical presentations of the disease in order to make early diagnosis and proper treatment possible, and break the transmission chain.The authors report a rare type of multibacillary leprosy: histoid leprosy and present images of numerous well-circumscribed indurated papules and nodules distributed throughout the entire body.

View Article: PubMed Central - PubMed

Affiliation: Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil.

ABSTRACT
AbstractLeprosy is a neglected disease. We point up the need of recognizing the unusual clinical presentations of the disease in order to make early diagnosis and proper treatment possible, and break the transmission chain. The authors report a rare type of multibacillary leprosy: histoid leprosy and present images of numerous well-circumscribed indurated papules and nodules distributed throughout the entire body.

No MeSH data available.


Related in: MedlinePlus