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First case of congenital idiopathic hypohidrosis in China.

Shi G, Zhu CY, Zhou Y, Yang YP, Fan YM - An Bras Dermatol (2015)

Bottom Line: AbstractA 43-year-old Chinese man presented with generalized hypohidrosis, which he had had since birth, without obvious abnormalities of other skin appendages except a sparse beard and axillary hairs.Histopathologic examination showed that the sweat glands were absent in the forearm and thigh, but some eccrine and apocrine sweat glands were present in the right axilla.S-100 was expressed in the nerve terminals surrounding the acini and ducts of the eccrine sweat glands, while PGP9.5 was positive in the acini of apocrine glands and the nerve terminals surrounding the eccrine glands in the axilla.

View Article: PubMed Central - PubMed

Affiliation: Guangdong Medical College, Guangdong, China.

ABSTRACT
AbstractA 43-year-old Chinese man presented with generalized hypohidrosis, which he had had since birth, without obvious abnormalities of other skin appendages except a sparse beard and axillary hairs. The sweat test revealed localized sweating on the face, axillae and palms. Histopathologic examination showed that the sweat glands were absent in the forearm and thigh, but some eccrine and apocrine sweat glands were present in the right axilla. S-100 was expressed in the nerve terminals surrounding the acini and ducts of the eccrine sweat glands, while PGP9.5 was positive in the acini of apocrine glands and the nerve terminals surrounding the eccrine glands in the axilla. To our knowledge, this is the first case of congenital idiopathic hypohidrosis in China.

No MeSH data available.


Related in: MedlinePlus

Iodine-starch test: A. Blue-black stain on forehead, cheeks and chin,with a sparse beard; B. Blueblack stain on both axillae, with sparseaxillary hairs
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f01: Iodine-starch test: A. Blue-black stain on forehead, cheeks and chin,with a sparse beard; B. Blueblack stain on both axillae, with sparseaxillary hairs

Mentions: Examination revealed generalized dry skin with mild palmoplantar hyperkeratosis. Thefacies, hair and teeth and nails were normal but his beard and axillary hairs weresparse (Figure 1). In addition, his generalhealth, intelligence, neurologic and ophthalmologic examination, and electrocardiographyand abdominal ultrasonography were all normal. Furthermore, the complete blood count andurinalysis, general biochemical profile, thyroid function and cholinesterase levels werewithin normal limits.


First case of congenital idiopathic hypohidrosis in China.

Shi G, Zhu CY, Zhou Y, Yang YP, Fan YM - An Bras Dermatol (2015)

Iodine-starch test: A. Blue-black stain on forehead, cheeks and chin,with a sparse beard; B. Blueblack stain on both axillae, with sparseaxillary hairs
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4631239&req=5

f01: Iodine-starch test: A. Blue-black stain on forehead, cheeks and chin,with a sparse beard; B. Blueblack stain on both axillae, with sparseaxillary hairs
Mentions: Examination revealed generalized dry skin with mild palmoplantar hyperkeratosis. Thefacies, hair and teeth and nails were normal but his beard and axillary hairs weresparse (Figure 1). In addition, his generalhealth, intelligence, neurologic and ophthalmologic examination, and electrocardiographyand abdominal ultrasonography were all normal. Furthermore, the complete blood count andurinalysis, general biochemical profile, thyroid function and cholinesterase levels werewithin normal limits.

Bottom Line: AbstractA 43-year-old Chinese man presented with generalized hypohidrosis, which he had had since birth, without obvious abnormalities of other skin appendages except a sparse beard and axillary hairs.Histopathologic examination showed that the sweat glands were absent in the forearm and thigh, but some eccrine and apocrine sweat glands were present in the right axilla.S-100 was expressed in the nerve terminals surrounding the acini and ducts of the eccrine sweat glands, while PGP9.5 was positive in the acini of apocrine glands and the nerve terminals surrounding the eccrine glands in the axilla.

View Article: PubMed Central - PubMed

Affiliation: Guangdong Medical College, Guangdong, China.

ABSTRACT
AbstractA 43-year-old Chinese man presented with generalized hypohidrosis, which he had had since birth, without obvious abnormalities of other skin appendages except a sparse beard and axillary hairs. The sweat test revealed localized sweating on the face, axillae and palms. Histopathologic examination showed that the sweat glands were absent in the forearm and thigh, but some eccrine and apocrine sweat glands were present in the right axilla. S-100 was expressed in the nerve terminals surrounding the acini and ducts of the eccrine sweat glands, while PGP9.5 was positive in the acini of apocrine glands and the nerve terminals surrounding the eccrine glands in the axilla. To our knowledge, this is the first case of congenital idiopathic hypohidrosis in China.

No MeSH data available.


Related in: MedlinePlus