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Leprosy in a University Hospital in Southern Brazil.

Lima AS, Pinto KC, Bona MP, Mattos SM, Hoffmann MP, Mulinari-Brenner FA, Ottoboni VC - An Bras Dermatol (2015)

Bottom Line: Neural enlargement was found in more than 50% of the patients and 48.44% of them developed reactional states.Hemolysis was the most commonly detected drug side effect.The most prevalent associated disease was hypertension.

View Article: PubMed Central - PubMed

Affiliation: Private Clinic, Brusque, SC, Brazil.

ABSTRACT

Unlabelled: Abstract

Background: Leprosy is an infectious disease that may lead to irreversible nerve damage, compromising patient's quality of life and leading to loss of working years.

Objectives: To evaluate the epidemiological profile of patients followed at a University Hospital.

Materials and methods: This is a retrospective observational study, based on a review of medical records. We studied the clinical and epidemiological features of patients with leprosy monitored at the Hospital de Clínicas of the Federal University of Paraná between January 2005 and January 2010.

Results: The mean age was 47.51, while 35.94% of patients were aged 41-60. The male:female rate was 1.8:1. The most prevalent occupations were: retired, students or rural workers. Patients came mainly from Curitiba or nearby areas, but there were also patients from the countryside. The mean diagnostic delay was 24.57 months. Multibacillary forms prevailed, with the lepromatous variety being the most common, closely followed by the borderline type. Neural enlargement was found in more than 50% of the patients and 48.44% of them developed reactional states. Hemolysis was the most commonly detected drug side effect. Initial functional evaluation was possible in 70% of patients, 55% of whom had disabilities upon diagnosis. The most prevalent associated disease was hypertension.

Conclusions: This study showed an important diagnostic delay and a high rate of sequelae in this specific population. Brazil is one of the few remaining countries that has not yet eradicated leprosy and it is important to improve health policies in order to prevent sequelae and achieve eradication.

No MeSH data available.


Related in: MedlinePlus

Neural Thickening. Neural Thickening frequency, showing that the ulnar nerve wasthe most commonly affected
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f04: Neural Thickening. Neural Thickening frequency, showing that the ulnar nerve wasthe most commonly affected

Mentions: Neural thickening was detected in 57.81% of patients during clinical examination. Theulnar nerve was the most commonly affected (51.56% of the cases), followed by thetibial, fibular (peroneal) and great auricular nerves, with 6.25% each (Graph 4).


Leprosy in a University Hospital in Southern Brazil.

Lima AS, Pinto KC, Bona MP, Mattos SM, Hoffmann MP, Mulinari-Brenner FA, Ottoboni VC - An Bras Dermatol (2015)

Neural Thickening. Neural Thickening frequency, showing that the ulnar nerve wasthe most commonly affected
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4631230&req=5

f04: Neural Thickening. Neural Thickening frequency, showing that the ulnar nerve wasthe most commonly affected
Mentions: Neural thickening was detected in 57.81% of patients during clinical examination. Theulnar nerve was the most commonly affected (51.56% of the cases), followed by thetibial, fibular (peroneal) and great auricular nerves, with 6.25% each (Graph 4).

Bottom Line: Neural enlargement was found in more than 50% of the patients and 48.44% of them developed reactional states.Hemolysis was the most commonly detected drug side effect.The most prevalent associated disease was hypertension.

View Article: PubMed Central - PubMed

Affiliation: Private Clinic, Brusque, SC, Brazil.

ABSTRACT

Unlabelled: Abstract

Background: Leprosy is an infectious disease that may lead to irreversible nerve damage, compromising patient's quality of life and leading to loss of working years.

Objectives: To evaluate the epidemiological profile of patients followed at a University Hospital.

Materials and methods: This is a retrospective observational study, based on a review of medical records. We studied the clinical and epidemiological features of patients with leprosy monitored at the Hospital de Clínicas of the Federal University of Paraná between January 2005 and January 2010.

Results: The mean age was 47.51, while 35.94% of patients were aged 41-60. The male:female rate was 1.8:1. The most prevalent occupations were: retired, students or rural workers. Patients came mainly from Curitiba or nearby areas, but there were also patients from the countryside. The mean diagnostic delay was 24.57 months. Multibacillary forms prevailed, with the lepromatous variety being the most common, closely followed by the borderline type. Neural enlargement was found in more than 50% of the patients and 48.44% of them developed reactional states. Hemolysis was the most commonly detected drug side effect. Initial functional evaluation was possible in 70% of patients, 55% of whom had disabilities upon diagnosis. The most prevalent associated disease was hypertension.

Conclusions: This study showed an important diagnostic delay and a high rate of sequelae in this specific population. Brazil is one of the few remaining countries that has not yet eradicated leprosy and it is important to improve health policies in order to prevent sequelae and achieve eradication.

No MeSH data available.


Related in: MedlinePlus