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Leprosy in a University Hospital in Southern Brazil.

Lima AS, Pinto KC, Bona MP, Mattos SM, Hoffmann MP, Mulinari-Brenner FA, Ottoboni VC - An Bras Dermatol (2015)

Bottom Line: Neural enlargement was found in more than 50% of the patients and 48.44% of them developed reactional states.Hemolysis was the most commonly detected drug side effect.The most prevalent associated disease was hypertension.

View Article: PubMed Central - PubMed

Affiliation: Private Clinic, Brusque, SC, Brazil.

ABSTRACT

Unlabelled: Abstract

Background: Leprosy is an infectious disease that may lead to irreversible nerve damage, compromising patient's quality of life and leading to loss of working years.

Objectives: To evaluate the epidemiological profile of patients followed at a University Hospital.

Materials and methods: This is a retrospective observational study, based on a review of medical records. We studied the clinical and epidemiological features of patients with leprosy monitored at the Hospital de Clínicas of the Federal University of Paraná between January 2005 and January 2010.

Results: The mean age was 47.51, while 35.94% of patients were aged 41-60. The male:female rate was 1.8:1. The most prevalent occupations were: retired, students or rural workers. Patients came mainly from Curitiba or nearby areas, but there were also patients from the countryside. The mean diagnostic delay was 24.57 months. Multibacillary forms prevailed, with the lepromatous variety being the most common, closely followed by the borderline type. Neural enlargement was found in more than 50% of the patients and 48.44% of them developed reactional states. Hemolysis was the most commonly detected drug side effect. Initial functional evaluation was possible in 70% of patients, 55% of whom had disabilities upon diagnosis. The most prevalent associated disease was hypertension.

Conclusions: This study showed an important diagnostic delay and a high rate of sequelae in this specific population. Brazil is one of the few remaining countries that has not yet eradicated leprosy and it is important to improve health policies in order to prevent sequelae and achieve eradication.

No MeSH data available.


Related in: MedlinePlus

Age range of patients, showing that the disease is more prevalent during theirworking years
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f01: Age range of patients, showing that the disease is more prevalent during theirworking years

Mentions: Eighty-one patients were examined in Dermatology's Leprosy outpatient clinic during theperiod. Sixty-four were eligible for this study. Among these cases, the mean age was47.51 years. Fifteen patients were younger than 20 (7.81%), twenty (31.25%) were aged20-40, twenty-three (35.94%) were aged 41-60, while sixteen patients (25%) were agedover 60 (Graph 1). According to SINAN, during thisperiod, a total of 9.169 cases were reported across the state, involving mostly peopleaged over 15.


Leprosy in a University Hospital in Southern Brazil.

Lima AS, Pinto KC, Bona MP, Mattos SM, Hoffmann MP, Mulinari-Brenner FA, Ottoboni VC - An Bras Dermatol (2015)

Age range of patients, showing that the disease is more prevalent during theirworking years
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4631230&req=5

f01: Age range of patients, showing that the disease is more prevalent during theirworking years
Mentions: Eighty-one patients were examined in Dermatology's Leprosy outpatient clinic during theperiod. Sixty-four were eligible for this study. Among these cases, the mean age was47.51 years. Fifteen patients were younger than 20 (7.81%), twenty (31.25%) were aged20-40, twenty-three (35.94%) were aged 41-60, while sixteen patients (25%) were agedover 60 (Graph 1). According to SINAN, during thisperiod, a total of 9.169 cases were reported across the state, involving mostly peopleaged over 15.

Bottom Line: Neural enlargement was found in more than 50% of the patients and 48.44% of them developed reactional states.Hemolysis was the most commonly detected drug side effect.The most prevalent associated disease was hypertension.

View Article: PubMed Central - PubMed

Affiliation: Private Clinic, Brusque, SC, Brazil.

ABSTRACT

Unlabelled: Abstract

Background: Leprosy is an infectious disease that may lead to irreversible nerve damage, compromising patient's quality of life and leading to loss of working years.

Objectives: To evaluate the epidemiological profile of patients followed at a University Hospital.

Materials and methods: This is a retrospective observational study, based on a review of medical records. We studied the clinical and epidemiological features of patients with leprosy monitored at the Hospital de Clínicas of the Federal University of Paraná between January 2005 and January 2010.

Results: The mean age was 47.51, while 35.94% of patients were aged 41-60. The male:female rate was 1.8:1. The most prevalent occupations were: retired, students or rural workers. Patients came mainly from Curitiba or nearby areas, but there were also patients from the countryside. The mean diagnostic delay was 24.57 months. Multibacillary forms prevailed, with the lepromatous variety being the most common, closely followed by the borderline type. Neural enlargement was found in more than 50% of the patients and 48.44% of them developed reactional states. Hemolysis was the most commonly detected drug side effect. Initial functional evaluation was possible in 70% of patients, 55% of whom had disabilities upon diagnosis. The most prevalent associated disease was hypertension.

Conclusions: This study showed an important diagnostic delay and a high rate of sequelae in this specific population. Brazil is one of the few remaining countries that has not yet eradicated leprosy and it is important to improve health policies in order to prevent sequelae and achieve eradication.

No MeSH data available.


Related in: MedlinePlus