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Biomonitoring of Lead, Cadmium, Total Mercury, and Methylmercury Levels in Maternal Blood and in Umbilical Cord Blood at Birth in South Korea.

Kim YM, Chung JY, An HS, Park SY, Kim BG, Bae JW, Han M, Cho YJ, Hong YS - Int J Environ Res Public Health (2015)

Bottom Line: With rising concerns of heavy metal exposure in pregnancy and early childhood, this study was conducted to assess the relationship between the lead, cadmium, mercury, and methylmercury blood levels in pregnancy and neonatal period.The geometric mean maternal blood levels of lead, cadmium, total mercury, and methylmercury at the second trimester were 1.02 ± 1.39 µg/dL, 0.61 ± 1.51 µg/L, 2.97 ± 1.45 µg/L, and 2.39 ± 1.45 µg/L, respectively, and in the newborns, these levels at birth were 0.71 ± 1.42 µg/dL, 0.01 ± 5.31 µg/L, 4.44 ± 1.49 µg/L, and 3.67 ± 1.51 µg/L, respectively.The mean ratios of lead, cadmium, total mercury, and methylmercury levels in the newborns to those in the mothers were 0.72, 0.04, 1.76, and 1.81, respectively.

View Article: PubMed Central - PubMed

Affiliation: Department of Preventive Medicine and Dong-A University Heavy Metal Exposure Environmental Health Center, Dong-A University College of Medicine, 49201 Busan, Korea. kimyumi@dau.ac.kr.

ABSTRACT
With rising concerns of heavy metal exposure in pregnancy and early childhood, this study was conducted to assess the relationship between the lead, cadmium, mercury, and methylmercury blood levels in pregnancy and neonatal period. The study population included 104 mothers and their children pairs who completed both baseline maternal blood sampling at the second trimester and umbilical cord blood sampling at birth. The geometric mean maternal blood levels of lead, cadmium, total mercury, and methylmercury at the second trimester were 1.02 ± 1.39 µg/dL, 0.61 ± 1.51 µg/L, 2.97 ± 1.45 µg/L, and 2.39 ± 1.45 µg/L, respectively, and in the newborns, these levels at birth were 0.71 ± 1.42 µg/dL, 0.01 ± 5.31 µg/L, 4.44 ± 1.49 µg/L, and 3.67 ± 1.51 µg/L, respectively. The mean ratios of lead, cadmium, total mercury, and methylmercury levels in the newborns to those in the mothers were 0.72, 0.04, 1.76, and 1.81, respectively. The levels of most heavy metals in pregnant women and infants were higher in this study than in studies from industrialized western countries. The placenta appears to protect fetuses from cadmium; however, total mercury and methylmercury were able to cross the placenta and accumulate in fetuses.

No MeSH data available.


Related in: MedlinePlus

Scatter plots and Spearman’s correlation analysis between maternal blood levels of heavy metals at the delivery and newborn blood levels of heavy metals at birth from 79 pairs. Abbreviations: ρ, Spearman’s correlation coefficient; CI, confidence interval.
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ijerph-12-13482-f002: Scatter plots and Spearman’s correlation analysis between maternal blood levels of heavy metals at the delivery and newborn blood levels of heavy metals at birth from 79 pairs. Abbreviations: ρ, Spearman’s correlation coefficient; CI, confidence interval.

Mentions: Using scatter plots and Spearman’s correlation analysis, linear trends were noted between maternal blood levels of heavy metals at delivery and newborn blood levels of heavy metals at birth from 79 mother-child pairs (Figure 2).


Biomonitoring of Lead, Cadmium, Total Mercury, and Methylmercury Levels in Maternal Blood and in Umbilical Cord Blood at Birth in South Korea.

Kim YM, Chung JY, An HS, Park SY, Kim BG, Bae JW, Han M, Cho YJ, Hong YS - Int J Environ Res Public Health (2015)

Scatter plots and Spearman’s correlation analysis between maternal blood levels of heavy metals at the delivery and newborn blood levels of heavy metals at birth from 79 pairs. Abbreviations: ρ, Spearman’s correlation coefficient; CI, confidence interval.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4627044&req=5

ijerph-12-13482-f002: Scatter plots and Spearman’s correlation analysis between maternal blood levels of heavy metals at the delivery and newborn blood levels of heavy metals at birth from 79 pairs. Abbreviations: ρ, Spearman’s correlation coefficient; CI, confidence interval.
Mentions: Using scatter plots and Spearman’s correlation analysis, linear trends were noted between maternal blood levels of heavy metals at delivery and newborn blood levels of heavy metals at birth from 79 mother-child pairs (Figure 2).

Bottom Line: With rising concerns of heavy metal exposure in pregnancy and early childhood, this study was conducted to assess the relationship between the lead, cadmium, mercury, and methylmercury blood levels in pregnancy and neonatal period.The geometric mean maternal blood levels of lead, cadmium, total mercury, and methylmercury at the second trimester were 1.02 ± 1.39 µg/dL, 0.61 ± 1.51 µg/L, 2.97 ± 1.45 µg/L, and 2.39 ± 1.45 µg/L, respectively, and in the newborns, these levels at birth were 0.71 ± 1.42 µg/dL, 0.01 ± 5.31 µg/L, 4.44 ± 1.49 µg/L, and 3.67 ± 1.51 µg/L, respectively.The mean ratios of lead, cadmium, total mercury, and methylmercury levels in the newborns to those in the mothers were 0.72, 0.04, 1.76, and 1.81, respectively.

View Article: PubMed Central - PubMed

Affiliation: Department of Preventive Medicine and Dong-A University Heavy Metal Exposure Environmental Health Center, Dong-A University College of Medicine, 49201 Busan, Korea. kimyumi@dau.ac.kr.

ABSTRACT
With rising concerns of heavy metal exposure in pregnancy and early childhood, this study was conducted to assess the relationship between the lead, cadmium, mercury, and methylmercury blood levels in pregnancy and neonatal period. The study population included 104 mothers and their children pairs who completed both baseline maternal blood sampling at the second trimester and umbilical cord blood sampling at birth. The geometric mean maternal blood levels of lead, cadmium, total mercury, and methylmercury at the second trimester were 1.02 ± 1.39 µg/dL, 0.61 ± 1.51 µg/L, 2.97 ± 1.45 µg/L, and 2.39 ± 1.45 µg/L, respectively, and in the newborns, these levels at birth were 0.71 ± 1.42 µg/dL, 0.01 ± 5.31 µg/L, 4.44 ± 1.49 µg/L, and 3.67 ± 1.51 µg/L, respectively. The mean ratios of lead, cadmium, total mercury, and methylmercury levels in the newborns to those in the mothers were 0.72, 0.04, 1.76, and 1.81, respectively. The levels of most heavy metals in pregnant women and infants were higher in this study than in studies from industrialized western countries. The placenta appears to protect fetuses from cadmium; however, total mercury and methylmercury were able to cross the placenta and accumulate in fetuses.

No MeSH data available.


Related in: MedlinePlus