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Elimination of Mother-To-Child Transmission of HIV Infection: The Drug Resource Enhancement against AIDS and Malnutrition Model.

Liotta G, Marazzi MC, Mothibi KE, Zimba I, Amangoua EE, Bonje EK, Bossiky BN, Robinson PA, Scarcella P, Musokotwane K, Palombi L, Germano P, Narciso P, de Luca A, Alumando E, Mamary SH, Magid NA, Guidotti G, Mancinelli S, Orlando S, Peroni M, Buonomo E, Nielsen-Saines K - Int J Environ Res Public Health (2015)

Bottom Line: Comprehensive strategies including peer-to-peer education, social support and laboratory monitoring can reduce refusals to less than 5% and attain retention rates approaching 90%.Several components of the model of care for reduction of HIV-1 MTCT are feasible and implementable in scale-up strategies.A review of this model of care for HIV eMTCT is provided.

View Article: PubMed Central - PubMed

Affiliation: University of Tor Vergata, 18-00173 Rome, Italy. giuseppeliotta@hotmail.com.

ABSTRACT
The Drug Resource Enhancement against AIDS and Malnutrition Program (DREAM) gathered professionals in the field of Elimination of HIV-Mother-To-Child Transmission (EMTCT) in Maputo in 2013 to discuss obstacles and solutions for the elimination of HIV vertical transmission in sub-Saharan Africa. During this workshop, the benefits of administrating combined antiretroviral therapy (cART) to HIV positive women from pregnancy throughout breastfeeding were reviewed. cART is capable of reducing vertical transmission to less than 5% at 24 months of age, as well as maternal mortality and infant mortality in both HIV infected and exposed populations to levels similar to those of uninfected individuals. The challenge for programs targeting eMTCT in developing countries is retention in care and treatment adherence. Both are intrinsically related to the model of care. The drop-out from eMTCT programs before cART initiation ranges from 33%-88% while retention rates at 18-24 months are less than 50%. Comprehensive strategies including peer-to-peer education, social support and laboratory monitoring can reduce refusals to less than 5% and attain retention rates approaching 90%. Several components of the model of care for reduction of HIV-1 MTCT are feasible and implementable in scale-up strategies. A review of this model of care for HIV eMTCT is provided.

No MeSH data available.


Related in: MedlinePlus

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ijerph-12-13224-f005: Electronic medical records.

Mentions: Electronic medical records: Use of electronic medical records is routine throughout the program centers with informatization of all patient data, including medical history and physical exams, laboratory data, appointments, medical encounters, prescription refills, and nutritional supplementation. This enables caretakers to plot virus load data, CD4 cell counts and body mass index data in real time while the patient is being evaluated as well as monitoring of adherence to prescriptions and medical visits [38] (Figure 5).


Elimination of Mother-To-Child Transmission of HIV Infection: The Drug Resource Enhancement against AIDS and Malnutrition Model.

Liotta G, Marazzi MC, Mothibi KE, Zimba I, Amangoua EE, Bonje EK, Bossiky BN, Robinson PA, Scarcella P, Musokotwane K, Palombi L, Germano P, Narciso P, de Luca A, Alumando E, Mamary SH, Magid NA, Guidotti G, Mancinelli S, Orlando S, Peroni M, Buonomo E, Nielsen-Saines K - Int J Environ Res Public Health (2015)

Electronic medical records.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4627027&req=5

ijerph-12-13224-f005: Electronic medical records.
Mentions: Electronic medical records: Use of electronic medical records is routine throughout the program centers with informatization of all patient data, including medical history and physical exams, laboratory data, appointments, medical encounters, prescription refills, and nutritional supplementation. This enables caretakers to plot virus load data, CD4 cell counts and body mass index data in real time while the patient is being evaluated as well as monitoring of adherence to prescriptions and medical visits [38] (Figure 5).

Bottom Line: Comprehensive strategies including peer-to-peer education, social support and laboratory monitoring can reduce refusals to less than 5% and attain retention rates approaching 90%.Several components of the model of care for reduction of HIV-1 MTCT are feasible and implementable in scale-up strategies.A review of this model of care for HIV eMTCT is provided.

View Article: PubMed Central - PubMed

Affiliation: University of Tor Vergata, 18-00173 Rome, Italy. giuseppeliotta@hotmail.com.

ABSTRACT
The Drug Resource Enhancement against AIDS and Malnutrition Program (DREAM) gathered professionals in the field of Elimination of HIV-Mother-To-Child Transmission (EMTCT) in Maputo in 2013 to discuss obstacles and solutions for the elimination of HIV vertical transmission in sub-Saharan Africa. During this workshop, the benefits of administrating combined antiretroviral therapy (cART) to HIV positive women from pregnancy throughout breastfeeding were reviewed. cART is capable of reducing vertical transmission to less than 5% at 24 months of age, as well as maternal mortality and infant mortality in both HIV infected and exposed populations to levels similar to those of uninfected individuals. The challenge for programs targeting eMTCT in developing countries is retention in care and treatment adherence. Both are intrinsically related to the model of care. The drop-out from eMTCT programs before cART initiation ranges from 33%-88% while retention rates at 18-24 months are less than 50%. Comprehensive strategies including peer-to-peer education, social support and laboratory monitoring can reduce refusals to less than 5% and attain retention rates approaching 90%. Several components of the model of care for reduction of HIV-1 MTCT are feasible and implementable in scale-up strategies. A review of this model of care for HIV eMTCT is provided.

No MeSH data available.


Related in: MedlinePlus