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In-situ Real-Time Monitoring of Volatile Organic Compound Exposure and Heart Rate Variability for Patients with Multiple Chemical Sensitivity.

Mizukoshi A, Kumagai K, Yamamoto N, Noguchi M, Yoshiuchi K, Kumano H, Sakabe K, Yanagisawa Y - Int J Environ Res Public Health (2015)

Bottom Line: The results revealed no significantly different parameters for averaged values such as VOC concentration, HF (high frequency), and LF (low frequency) to HF ratio compared with previous data from healthy subjects (Int.Environ.Based on these characteristics, prevention measures of symptoms for each subject may be proposed.

View Article: PubMed Central - PubMed

Affiliation: Department of Environmental Medicine and Behavioral Science, Kinki University Faculty of Medicine, 377-2, Ohno-higashi, Osakasayama, Osaka 589-8511, Japan. mizukoshi@med.kindai.ac.jp.

ABSTRACT
In-situ real-time monitoring of volatile organic compound (VOC) exposure and heart rate variability (HRV) were conducted for eight multiple chemical sensitivity (MCS) patients using a VOC monitor, a Holter monitor, and a time-activity questionnaire for 24 h to identify the relationship between VOC exposure, biological effects, and subjective symptoms in actual life. The results revealed no significantly different parameters for averaged values such as VOC concentration, HF (high frequency), and LF (low frequency) to HF ratio compared with previous data from healthy subjects (Int. J. Environ. Res. Public Health 2010, 7, 4127-4138). Significant negative correlations for four subjects were observed between HF and amounts of VOC change. These results suggest that some patients show inhibition of parasympathetic activities along with VOC exposure as observed in healthy subjects. Comparing the parameters during subjective symptoms and normal condition, VOC concentration and/or VOC change were high except for one subject. HF values were low for five subjects during subjective symptoms. Examining the time-series data for VOC exposure and HF of each subject showed that the subjective symptoms, VOC exposure, and HF seemed well related in some symptoms. Based on these characteristics, prevention measures of symptoms for each subject may be proposed.

No MeSH data available.


Related in: MedlinePlus

Time-series data of VOC concentration and log10 HF (subject H). Subjective symptoms and personal activities are indicated in upper side and locations are indicated in lower side. The values on subjective symptoms are symptom levels.
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ijerph-12-12446-f010: Time-series data of VOC concentration and log10 HF (subject H). Subjective symptoms and personal activities are indicated in upper side and locations are indicated in lower side. The values on subjective symptoms are symptom levels.

Mentions: Subject H was a 54-year-old female and a company owner. Figure 10 shows time-series data of VOC concentration and log10 HF of subject H. After decrease in HF, the subjective symptom appeared during relatively high concentration at 21:55. For other symptoms, consistent tendencies were not observed between VOC exposure, symptoms, and HF.


In-situ Real-Time Monitoring of Volatile Organic Compound Exposure and Heart Rate Variability for Patients with Multiple Chemical Sensitivity.

Mizukoshi A, Kumagai K, Yamamoto N, Noguchi M, Yoshiuchi K, Kumano H, Sakabe K, Yanagisawa Y - Int J Environ Res Public Health (2015)

Time-series data of VOC concentration and log10 HF (subject H). Subjective symptoms and personal activities are indicated in upper side and locations are indicated in lower side. The values on subjective symptoms are symptom levels.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4626978&req=5

ijerph-12-12446-f010: Time-series data of VOC concentration and log10 HF (subject H). Subjective symptoms and personal activities are indicated in upper side and locations are indicated in lower side. The values on subjective symptoms are symptom levels.
Mentions: Subject H was a 54-year-old female and a company owner. Figure 10 shows time-series data of VOC concentration and log10 HF of subject H. After decrease in HF, the subjective symptom appeared during relatively high concentration at 21:55. For other symptoms, consistent tendencies were not observed between VOC exposure, symptoms, and HF.

Bottom Line: The results revealed no significantly different parameters for averaged values such as VOC concentration, HF (high frequency), and LF (low frequency) to HF ratio compared with previous data from healthy subjects (Int.Environ.Based on these characteristics, prevention measures of symptoms for each subject may be proposed.

View Article: PubMed Central - PubMed

Affiliation: Department of Environmental Medicine and Behavioral Science, Kinki University Faculty of Medicine, 377-2, Ohno-higashi, Osakasayama, Osaka 589-8511, Japan. mizukoshi@med.kindai.ac.jp.

ABSTRACT
In-situ real-time monitoring of volatile organic compound (VOC) exposure and heart rate variability (HRV) were conducted for eight multiple chemical sensitivity (MCS) patients using a VOC monitor, a Holter monitor, and a time-activity questionnaire for 24 h to identify the relationship between VOC exposure, biological effects, and subjective symptoms in actual life. The results revealed no significantly different parameters for averaged values such as VOC concentration, HF (high frequency), and LF (low frequency) to HF ratio compared with previous data from healthy subjects (Int. J. Environ. Res. Public Health 2010, 7, 4127-4138). Significant negative correlations for four subjects were observed between HF and amounts of VOC change. These results suggest that some patients show inhibition of parasympathetic activities along with VOC exposure as observed in healthy subjects. Comparing the parameters during subjective symptoms and normal condition, VOC concentration and/or VOC change were high except for one subject. HF values were low for five subjects during subjective symptoms. Examining the time-series data for VOC exposure and HF of each subject showed that the subjective symptoms, VOC exposure, and HF seemed well related in some symptoms. Based on these characteristics, prevention measures of symptoms for each subject may be proposed.

No MeSH data available.


Related in: MedlinePlus