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Clinical application of sartorius tendon transposition during radical vulvectomy: a case control study of 58 cases at a single institution.

Li L, Kou X, Feng X, Liu F, Chao H, Wang L - J Gynecol Oncol (2015)

Bottom Line: No significant differences were found at median surgical times and amounts of bleeding (p=0.316 and p=0.249, respectively), neither at the incidences of groin cellulitis and lymphocele (p=0.673 and p=0.473, respectively), but the recovery times of the inguinal wounds were shorter (p=0.026) and the incidences of wound break and chronic lymphedema were significantly decreased in the tendon transposition group (p=0.012 and p=0.022, respectively).Postoperative quality of life in tendon transposition group was significantly improved as indicated by the EORTC QLQ-C30 questionnaire.Recurrences were similar (p=0.346) and no significant differences were found at PFS and OS (p=0.990 and p=0.683, respectively).

View Article: PubMed Central - PubMed

Affiliation: Department of Gynecologic Oncology, Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou, China. lilei04301596@163.com.

ABSTRACT

Objective: The aim of this study was to investigate the clinical effects of sartorius tendon transposition versus sartorius transposition during bilateral inguinal lymphadenectomy of radical vulvectomy.

Methods: A total of 58 vulvar cancer patients who had surgery from May 2007 to October 2013, in which 30 patients received sartorius transposition and 28 patients received sartorius tendon transposition. All patients were matched by age, body mass index, stage, histology, and grade. Intraoperative variables and postoperative complications, recurrence, progression-free survival (PFS), and overall survival (OS) and postoperative life quality were compared and analyzed.

Results: No significant differences were found at median surgical times and amounts of bleeding (p=0.316 and p=0.249, respectively), neither at the incidences of groin cellulitis and lymphocele (p=0.673 and p=0.473, respectively), but the recovery times of the inguinal wounds were shorter (p=0.026) and the incidences of wound break and chronic lymphedema were significantly decreased in the tendon transposition group (p=0.012 and p=0.022, respectively). Postoperative quality of life in tendon transposition group was significantly improved as indicated by the EORTC QLQ-C30 questionnaire. Recurrences were similar (p=0.346) and no significant differences were found at PFS and OS (p=0.990 and p=0.683, respectively).

Conclusion: Compared to sartorius transposition, sartorius tendon transposition during inguinal lymphadenectomy led to improved patient recovery, reduced postoperative complications, and improved life quality without compromising the outcomes.

No MeSH data available.


Related in: MedlinePlus

Kaplan-Meier survival curves for the (A) progression-free survival (PFS) and (B) overall survival (OS) of the patients. No significance differences in PFS (p=0.990) or OS (p=0.683) were found.
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Figure 3: Kaplan-Meier survival curves for the (A) progression-free survival (PFS) and (B) overall survival (OS) of the patients. No significance differences in PFS (p=0.990) or OS (p=0.683) were found.

Mentions: During the postoperative follow-up, seven patients in the sartorius transposition group experienced recurrences that included two cases of vulvar recurrence, three cases of inguinal region lymph node recurrence, and two cases of distant metastasis. There were six recurrences in the tendon transposition-treated group that included three case of inguinal region lymph node recurrence, one case of pelvic recurrence, and two cases of distant metastasis. The postoperative recurrence rates of the sartorius transposition and tendon transposition groups were 23.3% and 21.4%. The median PFS at sartorius transposition group and tendon transposition group were 66.0% and 60.0% (Fig. 3A). Corresponding figures for OS were 68.7% and 75.4% (Fig. 3B). The log-rank test on PFS and OS did not show significant difference between two groups (p=0.990 and p=0.683, respectively).


Clinical application of sartorius tendon transposition during radical vulvectomy: a case control study of 58 cases at a single institution.

Li L, Kou X, Feng X, Liu F, Chao H, Wang L - J Gynecol Oncol (2015)

Kaplan-Meier survival curves for the (A) progression-free survival (PFS) and (B) overall survival (OS) of the patients. No significance differences in PFS (p=0.990) or OS (p=0.683) were found.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4620369&req=5

Figure 3: Kaplan-Meier survival curves for the (A) progression-free survival (PFS) and (B) overall survival (OS) of the patients. No significance differences in PFS (p=0.990) or OS (p=0.683) were found.
Mentions: During the postoperative follow-up, seven patients in the sartorius transposition group experienced recurrences that included two cases of vulvar recurrence, three cases of inguinal region lymph node recurrence, and two cases of distant metastasis. There were six recurrences in the tendon transposition-treated group that included three case of inguinal region lymph node recurrence, one case of pelvic recurrence, and two cases of distant metastasis. The postoperative recurrence rates of the sartorius transposition and tendon transposition groups were 23.3% and 21.4%. The median PFS at sartorius transposition group and tendon transposition group were 66.0% and 60.0% (Fig. 3A). Corresponding figures for OS were 68.7% and 75.4% (Fig. 3B). The log-rank test on PFS and OS did not show significant difference between two groups (p=0.990 and p=0.683, respectively).

Bottom Line: No significant differences were found at median surgical times and amounts of bleeding (p=0.316 and p=0.249, respectively), neither at the incidences of groin cellulitis and lymphocele (p=0.673 and p=0.473, respectively), but the recovery times of the inguinal wounds were shorter (p=0.026) and the incidences of wound break and chronic lymphedema were significantly decreased in the tendon transposition group (p=0.012 and p=0.022, respectively).Postoperative quality of life in tendon transposition group was significantly improved as indicated by the EORTC QLQ-C30 questionnaire.Recurrences were similar (p=0.346) and no significant differences were found at PFS and OS (p=0.990 and p=0.683, respectively).

View Article: PubMed Central - PubMed

Affiliation: Department of Gynecologic Oncology, Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou, China. lilei04301596@163.com.

ABSTRACT

Objective: The aim of this study was to investigate the clinical effects of sartorius tendon transposition versus sartorius transposition during bilateral inguinal lymphadenectomy of radical vulvectomy.

Methods: A total of 58 vulvar cancer patients who had surgery from May 2007 to October 2013, in which 30 patients received sartorius transposition and 28 patients received sartorius tendon transposition. All patients were matched by age, body mass index, stage, histology, and grade. Intraoperative variables and postoperative complications, recurrence, progression-free survival (PFS), and overall survival (OS) and postoperative life quality were compared and analyzed.

Results: No significant differences were found at median surgical times and amounts of bleeding (p=0.316 and p=0.249, respectively), neither at the incidences of groin cellulitis and lymphocele (p=0.673 and p=0.473, respectively), but the recovery times of the inguinal wounds were shorter (p=0.026) and the incidences of wound break and chronic lymphedema were significantly decreased in the tendon transposition group (p=0.012 and p=0.022, respectively). Postoperative quality of life in tendon transposition group was significantly improved as indicated by the EORTC QLQ-C30 questionnaire. Recurrences were similar (p=0.346) and no significant differences were found at PFS and OS (p=0.990 and p=0.683, respectively).

Conclusion: Compared to sartorius transposition, sartorius tendon transposition during inguinal lymphadenectomy led to improved patient recovery, reduced postoperative complications, and improved life quality without compromising the outcomes.

No MeSH data available.


Related in: MedlinePlus