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Eosinophilic Liver Infiltration.

Santiago Rivera L, Figueroa Rivera I, Toro DH, Gutierrez J, Acosta E - ACG Case Rep J (2015)

Bottom Line: Eosinophilic liver infiltration is a commonly encountered focal eosinophil-related inflammation with or without necrosis, which can be seen on computed tomography (CT) in the presence of peripheral eosinophilia.Although this entity has a relatively benign course, it is related to numerable conditions for which diagnosis may be challenging and requires substantial diagnostic work-up for proper management and care of the underlying disease.We report a case of a 60-year-old man who presented with a 1-week history of right upper quadrant abdominal pain with multiple ill-defined liver hypodensities associated with significant eosinophilia.

View Article: PubMed Central - PubMed

Affiliation: Department of Gastroenterology, VA Caribbean Healthcare System, San Juan, Puerto Rico.

ABSTRACT
Eosinophilic liver infiltration is a commonly encountered focal eosinophil-related inflammation with or without necrosis, which can be seen on computed tomography (CT) in the presence of peripheral eosinophilia. Although this entity has a relatively benign course, it is related to numerable conditions for which diagnosis may be challenging and requires substantial diagnostic work-up for proper management and care of the underlying disease. We report a case of a 60-year-old man who presented with a 1-week history of right upper quadrant abdominal pain with multiple ill-defined liver hypodensities associated with significant eosinophilia.

No MeSH data available.


Related in: MedlinePlus

Heterogeneous liver parenchyma with multiples hypoattenuating ill-defined lesions on the portal venous phase.
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Figure 1: Heterogeneous liver parenchyma with multiples hypoattenuating ill-defined lesions on the portal venous phase.

Mentions: On physical evaluation, the patient was afebrile with an abdomen tender to palpation in the right upper quadrant and epigastric region. Initial laboratories showed leukocytosis associated with marked eosinophilia, with a white blood cell count of 19,200/µL, and 60% eosinophils corresponding to a total eosinophil count of 11,520/µL. Liver enzymes and alkaline phosphatase were mildly elevated. Chest x-ray revealed clear and well-expanded lungs, with no consolidates or effusions. Abdominal/pelvic CT revealed heterogeneous attenuation of the liver with multiple, ill-defined hypodensities, mural thickening of the gastric wall, and multiple, sub-centimeter mesenteric and retroperitoneal adenopathies. A 1.4 x 2-cm portocaval adenopathy was also identified (Figure 1).


Eosinophilic Liver Infiltration.

Santiago Rivera L, Figueroa Rivera I, Toro DH, Gutierrez J, Acosta E - ACG Case Rep J (2015)

Heterogeneous liver parenchyma with multiples hypoattenuating ill-defined lesions on the portal venous phase.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4612763&req=5

Figure 1: Heterogeneous liver parenchyma with multiples hypoattenuating ill-defined lesions on the portal venous phase.
Mentions: On physical evaluation, the patient was afebrile with an abdomen tender to palpation in the right upper quadrant and epigastric region. Initial laboratories showed leukocytosis associated with marked eosinophilia, with a white blood cell count of 19,200/µL, and 60% eosinophils corresponding to a total eosinophil count of 11,520/µL. Liver enzymes and alkaline phosphatase were mildly elevated. Chest x-ray revealed clear and well-expanded lungs, with no consolidates or effusions. Abdominal/pelvic CT revealed heterogeneous attenuation of the liver with multiple, ill-defined hypodensities, mural thickening of the gastric wall, and multiple, sub-centimeter mesenteric and retroperitoneal adenopathies. A 1.4 x 2-cm portocaval adenopathy was also identified (Figure 1).

Bottom Line: Eosinophilic liver infiltration is a commonly encountered focal eosinophil-related inflammation with or without necrosis, which can be seen on computed tomography (CT) in the presence of peripheral eosinophilia.Although this entity has a relatively benign course, it is related to numerable conditions for which diagnosis may be challenging and requires substantial diagnostic work-up for proper management and care of the underlying disease.We report a case of a 60-year-old man who presented with a 1-week history of right upper quadrant abdominal pain with multiple ill-defined liver hypodensities associated with significant eosinophilia.

View Article: PubMed Central - PubMed

Affiliation: Department of Gastroenterology, VA Caribbean Healthcare System, San Juan, Puerto Rico.

ABSTRACT
Eosinophilic liver infiltration is a commonly encountered focal eosinophil-related inflammation with or without necrosis, which can be seen on computed tomography (CT) in the presence of peripheral eosinophilia. Although this entity has a relatively benign course, it is related to numerable conditions for which diagnosis may be challenging and requires substantial diagnostic work-up for proper management and care of the underlying disease. We report a case of a 60-year-old man who presented with a 1-week history of right upper quadrant abdominal pain with multiple ill-defined liver hypodensities associated with significant eosinophilia.

No MeSH data available.


Related in: MedlinePlus