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Metastatic Testicular Choriocarcinoma: A Rare Cause of Upper GI Bleeding.

Lowe K, Paterson J, Armstrong S, Walsh S, Groome M, Mowat C - ACG Case Rep J (2015)

Bottom Line: We present a case of upper gastrointestinal bleeding in an otherwise healthy 18-year-old man who presented with melena.Endoscopy revealed an ulcerated mass in the stomach and pathology confirmed this to be a malignant, poorly differentiated choriocarcinoma.Further imaging showed a left testicular mass with evidence of pulmonary, gastric, and brain metastases, and blood tests revealed an hCG level of 32,219 U/L.

View Article: PubMed Central - PubMed

Affiliation: Department of Gastroenterology, NHS Tayside, Dundee, United Kingdom.

ABSTRACT
We present a case of upper gastrointestinal bleeding in an otherwise healthy 18-year-old man who presented with melena. Endoscopy revealed an ulcerated mass in the stomach and pathology confirmed this to be a malignant, poorly differentiated choriocarcinoma. Further imaging showed a left testicular mass with evidence of pulmonary, gastric, and brain metastases, and blood tests revealed an hCG level of 32,219 U/L. He was diagnosed with advanced metastatic testicular choriocarcinoma and underwent intensive induction chemotherapy and an orchidectomy. Metastatic testicular choriocarcinoma is a rare cause of gastrointestinal bleeding.

No MeSH data available.


Related in: MedlinePlus

A 1.5-cm ulcerated mass on the lower body of the greater curve of the stomach.
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Figure 1: A 1.5-cm ulcerated mass on the lower body of the greater curve of the stomach.

Mentions: He had no significant past medical or family history. He took no regular medications and had no known drug allergies. He smoked 10 cigarettes a day, 3-4 g of cannabis per week, and was an occasional binge drinker. Admission laboratory values revealed a severe microcytic anemia with a hemoglobin of 4.7 g/dL. Following fluid resuscitation and blood transfusion, upper GI endoscopy revealed a 1.5-cm ulcerated mass on the lower body of the greater curve of the stomach (Figure 1). Biopsies revealed a poorly differentiated choriocarcinoma (Figure 2).


Metastatic Testicular Choriocarcinoma: A Rare Cause of Upper GI Bleeding.

Lowe K, Paterson J, Armstrong S, Walsh S, Groome M, Mowat C - ACG Case Rep J (2015)

A 1.5-cm ulcerated mass on the lower body of the greater curve of the stomach.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4612755&req=5

Figure 1: A 1.5-cm ulcerated mass on the lower body of the greater curve of the stomach.
Mentions: He had no significant past medical or family history. He took no regular medications and had no known drug allergies. He smoked 10 cigarettes a day, 3-4 g of cannabis per week, and was an occasional binge drinker. Admission laboratory values revealed a severe microcytic anemia with a hemoglobin of 4.7 g/dL. Following fluid resuscitation and blood transfusion, upper GI endoscopy revealed a 1.5-cm ulcerated mass on the lower body of the greater curve of the stomach (Figure 1). Biopsies revealed a poorly differentiated choriocarcinoma (Figure 2).

Bottom Line: We present a case of upper gastrointestinal bleeding in an otherwise healthy 18-year-old man who presented with melena.Endoscopy revealed an ulcerated mass in the stomach and pathology confirmed this to be a malignant, poorly differentiated choriocarcinoma.Further imaging showed a left testicular mass with evidence of pulmonary, gastric, and brain metastases, and blood tests revealed an hCG level of 32,219 U/L.

View Article: PubMed Central - PubMed

Affiliation: Department of Gastroenterology, NHS Tayside, Dundee, United Kingdom.

ABSTRACT
We present a case of upper gastrointestinal bleeding in an otherwise healthy 18-year-old man who presented with melena. Endoscopy revealed an ulcerated mass in the stomach and pathology confirmed this to be a malignant, poorly differentiated choriocarcinoma. Further imaging showed a left testicular mass with evidence of pulmonary, gastric, and brain metastases, and blood tests revealed an hCG level of 32,219 U/L. He was diagnosed with advanced metastatic testicular choriocarcinoma and underwent intensive induction chemotherapy and an orchidectomy. Metastatic testicular choriocarcinoma is a rare cause of gastrointestinal bleeding.

No MeSH data available.


Related in: MedlinePlus