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nextflu: real-time tracking of seasonal influenza virus evolution in humans.

Neher RA, Bedford T - Bioinformatics (2015)

Bottom Line: Seasonal influenza viruses evolve rapidly, allowing them to evade immunity in their human hosts and reinfect previously infected individuals.Similarly, vaccines against seasonal influenza need to be updated frequently to protect against an evolving virus population.We have thus developed a processing pipeline and browser-based visualization that allows convenient exploration and analysis of the most recent influenza virus sequence data.

View Article: PubMed Central - PubMed

Affiliation: Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany and.

No MeSH data available.


Related in: MedlinePlus

The nextflu website with the user interface on the left and the phylogenetic tree on the right
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Related In: Results  -  Collection

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btv381-F1: The nextflu website with the user interface on the left and the phylogenetic tree on the right

Mentions: At the end of the augur pipeline, JSON files are exported containing the annotated phylogenetic tree, sequence data and frequency trajectories. These JSON files are then visualized by auspice using D3 (Bostock et al., 2011) and a phylogenetic tree is displayed with branches scaled according to evolutionary distance across all sites (Fig. 1). The user can explore the data interactively by selecting viruses from different dates or by coloring the tree by attributes such as:


nextflu: real-time tracking of seasonal influenza virus evolution in humans.

Neher RA, Bedford T - Bioinformatics (2015)

The nextflu website with the user interface on the left and the phylogenetic tree on the right
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4612219&req=5

btv381-F1: The nextflu website with the user interface on the left and the phylogenetic tree on the right
Mentions: At the end of the augur pipeline, JSON files are exported containing the annotated phylogenetic tree, sequence data and frequency trajectories. These JSON files are then visualized by auspice using D3 (Bostock et al., 2011) and a phylogenetic tree is displayed with branches scaled according to evolutionary distance across all sites (Fig. 1). The user can explore the data interactively by selecting viruses from different dates or by coloring the tree by attributes such as:

Bottom Line: Seasonal influenza viruses evolve rapidly, allowing them to evade immunity in their human hosts and reinfect previously infected individuals.Similarly, vaccines against seasonal influenza need to be updated frequently to protect against an evolving virus population.We have thus developed a processing pipeline and browser-based visualization that allows convenient exploration and analysis of the most recent influenza virus sequence data.

View Article: PubMed Central - PubMed

Affiliation: Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany and.

No MeSH data available.


Related in: MedlinePlus