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Novel X-ray image noise reduction technology reduces patient radiation dose while maintaining image quality in coronary angiography.

Ten Cate T, van Wely M, Gehlmann H, Mauti M, Camaro C, Reifart N, Suryapranata H, de Boer MJ - Neth Heart J (2015)

Bottom Line: The consequences of high radiation dose for patient and staff demand constant improvements in X-ray dose reduction technology.The median dose area product per frame decreased from 55 to 26 mGy.cm(2)/frame (53 % reduction, p < 0.001).This study demonstrates that the novel X-ray imaging technology provides non-inferior image quality compared with conventional angiographic systems for interventional cardiology with a 53 % patient dose reduction.

View Article: PubMed Central - PubMed

Affiliation: Department of Interventional Cardiology, RadboudUMC, Geert Grooteplein-Zuid 22, 6525, Nijmegen, GA, The Netherlands. tim.tencate@radboudumc.nl.

ABSTRACT

Aims: The consequences of high radiation dose for patient and staff demand constant improvements in X-ray dose reduction technology. This study assessed non-inferiority of image quality and quantified patient dose reduction in interventional cardiology for an anatomy-specific optimised cine acquisition chain combined with advanced real-time image noise reduction algorithms referred to as 'study cine', compared with conventional angiography.

Methods: Fifty patients underwent two coronary angiographic acquisitions: one with advanced image processing and optimised exposure system settings to enable dose reduction (study cine) and one with standard image processing and exposure settings (reference cine). The image sets of 39 patients (18 females, 21 males) were rated by six experienced independent reviewers, blinded to the patient and image characteristics. The image pairs were randomly presented. Overall 85 % of the study cine images were rated as better or equal quality compared with the reference cine (95 % CI 0.81-0.90). The median dose area product per frame decreased from 55 to 26 mGy.cm(2)/frame (53 % reduction, p < 0.001).

Conclusion: This study demonstrates that the novel X-ray imaging technology provides non-inferior image quality compared with conventional angiographic systems for interventional cardiology with a 53 % patient dose reduction.

No MeSH data available.


Related in: MedlinePlus

Example of a 55-year-old female (BMI 30.2 kg/m2), current smoker with a medical history of hypertension, hyperlipidaemia and a family history of premature coronary artery disease (CAD). The patient already underwent PCI (stent in LAD and RCA) and was admitted for diagnostic procedure for complaints of progressive angina without symptoms at rest. The top panel, a represents the reference image and b the study image. Cine acquisitions obtained at 15 fps, field of view 20 cm, LAO 45 CRA 20 with (a) reference cine (DAP: 60.40 mGy.cm2/frame), (b) study cine (DAP: 27.01 mGy.cm2/frame)
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Fig3: Example of a 55-year-old female (BMI 30.2 kg/m2), current smoker with a medical history of hypertension, hyperlipidaemia and a family history of premature coronary artery disease (CAD). The patient already underwent PCI (stent in LAD and RCA) and was admitted for diagnostic procedure for complaints of progressive angina without symptoms at rest. The top panel, a represents the reference image and b the study image. Cine acquisitions obtained at 15 fps, field of view 20 cm, LAO 45 CRA 20 with (a) reference cine (DAP: 60.40 mGy.cm2/frame), (b) study cine (DAP: 27.01 mGy.cm2/frame)

Mentions: All images acquired with the study cine were of diagnostic quality to assess clinically relevant information. Overall, 85 % of the image sets were considered of better or equal (non-inferior) image quality compared with the reference cine (95 % CI 0.81–0.90) with the study cine considered better in 32 % of the images. Figs. 1 and 2 show the rating of the images in more detail for the complete group and for patients with BMI > 28 kg/m2, respectively. Fig. 3 shows an example of a study patient.Fig. 1


Novel X-ray image noise reduction technology reduces patient radiation dose while maintaining image quality in coronary angiography.

Ten Cate T, van Wely M, Gehlmann H, Mauti M, Camaro C, Reifart N, Suryapranata H, de Boer MJ - Neth Heart J (2015)

Example of a 55-year-old female (BMI 30.2 kg/m2), current smoker with a medical history of hypertension, hyperlipidaemia and a family history of premature coronary artery disease (CAD). The patient already underwent PCI (stent in LAD and RCA) and was admitted for diagnostic procedure for complaints of progressive angina without symptoms at rest. The top panel, a represents the reference image and b the study image. Cine acquisitions obtained at 15 fps, field of view 20 cm, LAO 45 CRA 20 with (a) reference cine (DAP: 60.40 mGy.cm2/frame), (b) study cine (DAP: 27.01 mGy.cm2/frame)
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4608924&req=5

Fig3: Example of a 55-year-old female (BMI 30.2 kg/m2), current smoker with a medical history of hypertension, hyperlipidaemia and a family history of premature coronary artery disease (CAD). The patient already underwent PCI (stent in LAD and RCA) and was admitted for diagnostic procedure for complaints of progressive angina without symptoms at rest. The top panel, a represents the reference image and b the study image. Cine acquisitions obtained at 15 fps, field of view 20 cm, LAO 45 CRA 20 with (a) reference cine (DAP: 60.40 mGy.cm2/frame), (b) study cine (DAP: 27.01 mGy.cm2/frame)
Mentions: All images acquired with the study cine were of diagnostic quality to assess clinically relevant information. Overall, 85 % of the image sets were considered of better or equal (non-inferior) image quality compared with the reference cine (95 % CI 0.81–0.90) with the study cine considered better in 32 % of the images. Figs. 1 and 2 show the rating of the images in more detail for the complete group and for patients with BMI > 28 kg/m2, respectively. Fig. 3 shows an example of a study patient.Fig. 1

Bottom Line: The consequences of high radiation dose for patient and staff demand constant improvements in X-ray dose reduction technology.The median dose area product per frame decreased from 55 to 26 mGy.cm(2)/frame (53 % reduction, p < 0.001).This study demonstrates that the novel X-ray imaging technology provides non-inferior image quality compared with conventional angiographic systems for interventional cardiology with a 53 % patient dose reduction.

View Article: PubMed Central - PubMed

Affiliation: Department of Interventional Cardiology, RadboudUMC, Geert Grooteplein-Zuid 22, 6525, Nijmegen, GA, The Netherlands. tim.tencate@radboudumc.nl.

ABSTRACT

Aims: The consequences of high radiation dose for patient and staff demand constant improvements in X-ray dose reduction technology. This study assessed non-inferiority of image quality and quantified patient dose reduction in interventional cardiology for an anatomy-specific optimised cine acquisition chain combined with advanced real-time image noise reduction algorithms referred to as 'study cine', compared with conventional angiography.

Methods: Fifty patients underwent two coronary angiographic acquisitions: one with advanced image processing and optimised exposure system settings to enable dose reduction (study cine) and one with standard image processing and exposure settings (reference cine). The image sets of 39 patients (18 females, 21 males) were rated by six experienced independent reviewers, blinded to the patient and image characteristics. The image pairs were randomly presented. Overall 85 % of the study cine images were rated as better or equal quality compared with the reference cine (95 % CI 0.81-0.90). The median dose area product per frame decreased from 55 to 26 mGy.cm(2)/frame (53 % reduction, p < 0.001).

Conclusion: This study demonstrates that the novel X-ray imaging technology provides non-inferior image quality compared with conventional angiographic systems for interventional cardiology with a 53 % patient dose reduction.

No MeSH data available.


Related in: MedlinePlus