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Ocular Tuberculosis with Progressive Unilateral Corneal Melting.

Bayraktutar BN, Uçakhan-Gündüz Ö - Case Rep Ophthalmol (2015)

Bottom Line: In this case report, we present a patient with ocular tuberculosis presenting with progressive unilateral corneal melting.A 47-year-old female was admitted with melting at the inferior half of the peripheral cornea and inferior subconjunctival nodules.In endemic areas, ocular tuberculosis should be kept in mind in the differential diagnosis of patients with chronic and atypical corneal involvement.

View Article: PubMed Central - PubMed

Affiliation: Ophthalmology Department, Ankara University Faculty of Medicine, Ankara, Turkey.

ABSTRACT

Objectives: In this case report, we present a patient with ocular tuberculosis presenting with progressive unilateral corneal melting.

Patient: A 47-year-old female was admitted with melting at the inferior half of the peripheral cornea and inferior subconjunctival nodules. Biopsy material of the nodules was negative for tuberculosis bacillus. However, polymerase chain reaction of the biopsy sample revealed the DNA of the bacillus, and the diagnosis was confirmed.

Conclusion: In endemic areas, ocular tuberculosis should be kept in mind in the differential diagnosis of patients with chronic and atypical corneal involvement.

No MeSH data available.


Related in: MedlinePlus

Histopathology specimen of the subconjunctival nodules showing granuloma formation (small arrow) and caseation necrosis (large arrow).
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Figure 3: Histopathology specimen of the subconjunctival nodules showing granuloma formation (small arrow) and caseation necrosis (large arrow).

Mentions: Total excisional biopsies of the subconjunctival nodules were performed. Histopathological examination of the samples revealed granulomatous inflammation with caseation necrosis surrounded by multinuclear giant cells and histiocytes (fig. 3, fig. 4). Ziehl-Neelsen staining for acid fast bacilli (AFB) was negative, but on evaluation of specimens with polymerase chain reaction (PCR). M. Tuberculosis DNA was demonstrated.


Ocular Tuberculosis with Progressive Unilateral Corneal Melting.

Bayraktutar BN, Uçakhan-Gündüz Ö - Case Rep Ophthalmol (2015)

Histopathology specimen of the subconjunctival nodules showing granuloma formation (small arrow) and caseation necrosis (large arrow).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4608636&req=5

Figure 3: Histopathology specimen of the subconjunctival nodules showing granuloma formation (small arrow) and caseation necrosis (large arrow).
Mentions: Total excisional biopsies of the subconjunctival nodules were performed. Histopathological examination of the samples revealed granulomatous inflammation with caseation necrosis surrounded by multinuclear giant cells and histiocytes (fig. 3, fig. 4). Ziehl-Neelsen staining for acid fast bacilli (AFB) was negative, but on evaluation of specimens with polymerase chain reaction (PCR). M. Tuberculosis DNA was demonstrated.

Bottom Line: In this case report, we present a patient with ocular tuberculosis presenting with progressive unilateral corneal melting.A 47-year-old female was admitted with melting at the inferior half of the peripheral cornea and inferior subconjunctival nodules.In endemic areas, ocular tuberculosis should be kept in mind in the differential diagnosis of patients with chronic and atypical corneal involvement.

View Article: PubMed Central - PubMed

Affiliation: Ophthalmology Department, Ankara University Faculty of Medicine, Ankara, Turkey.

ABSTRACT

Objectives: In this case report, we present a patient with ocular tuberculosis presenting with progressive unilateral corneal melting.

Patient: A 47-year-old female was admitted with melting at the inferior half of the peripheral cornea and inferior subconjunctival nodules. Biopsy material of the nodules was negative for tuberculosis bacillus. However, polymerase chain reaction of the biopsy sample revealed the DNA of the bacillus, and the diagnosis was confirmed.

Conclusion: In endemic areas, ocular tuberculosis should be kept in mind in the differential diagnosis of patients with chronic and atypical corneal involvement.

No MeSH data available.


Related in: MedlinePlus