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Heart Failure: An Exploration of Recent Advances in Research and Treatment (A).

Szema A, McLarty A, Skopicki H, Bloom M, Jermyn R - Clin Med Insights Cardiol (2015)

View Article: PubMed Central - PubMed

Affiliation: Adjunct Professor, College of Engineering and Applied Sciences, Department of Technology and Society, Stony Brook University, Stony Brook, NY, USA. Clinical Assistant Professor, Occupational and Environmental Medicine, Preventive Medicine, and Epidemiology, Department of Population Health, Hofstra North Shore LIJ School of Medicine, Hofstra University, Hempstead, NY, USA.

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The supplement aims to provide readers with an exploration of recent advances in research on and treatment of heart failure... Common etiological mechanisms of heart failure include coronary ischemia, valvular disease, hypertension, and diastolic dysfunction... Yet, other causes include: post-partum cardiomyopathy, post-infectious, chronic tachycardia, metabolic dysregulation, adverse medication side effects (particularly adriamycin chemotherapy), orphan disease Duchenne’s Muscular Dystrophy, infiltrative diseases (such as amyloidosis), and inflammatory/connective tissue diseases (such as systemic lupus erythematosus)... When known causes of heart failure are excluded then heart failure is classified as idiopathic... Less often studied versus chronic heart failure, is acute decompensated heart failure associated with abrupt-onset symptoms associated with hospitalization... Nearly half of admitted patients with heart failure have preserved ejection fraction., Survival among heart failure patients long-term may be improved with β-blockers, angiotensin converting enzyme inhibitors, aldosterone antagonists, electrophysiology devices such as automatic implantable cardiovascular defibrillators, and vasodilators... Other drugs such as digoxin and diuretics do not alter death rates–digoxin reduces hospitalizations, while diuretics (furosemide or lasix) improve symptoms... Another aspect of heart failure is diastolic dysfunction with preserved left ventricular ejection fraction, accounting for half of hospitalizations... Medications for diastolic dysfunction are similar to systolic dysfunction: ACE inhibitors, ARBs, diuretics, and β-blockers... Dr. McLarty presents a practical review and guideline for LVAD use... Dr. Fahad Gilani et al. discuss “Percutaneous Mechanical Support in Cardiogenic Shock: A Review” and note that mortality is not improved with Intra-Aortic Balloon Pumps (IABP), Extracorporeal Membrane Oxygenation (ECMO) or percutaneous LVADs... Finally, I would like to comment on “Reversible Cardiomyopathies” by Dr. Harsh Patel and co-authors, which reminds us to search the treatable, such as Sympathoexcitation-Induced Takotsubo Cardiomyopathy due to excess catecholamines from autonomic dysfunction... What this may hold for the short-term treatment of heart failure remains to be seen, but ultimately the goal will be to help us improve upon current practice... She now practices as a cardiologist specifically within heart failure and transplant... Dr Jermyn is the author or co-author of 5 published papers and has presented at 3 conferences in the 2014–2015 academic year, including HFSA and ACC.

No MeSH data available.


anthony.szema@stonybrook.eduhttp://www.stonybrook.edu/est/people/bios/aszema.shtml
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f1-cmc-suppl.2-2015-053: anthony.szema@stonybrook.eduhttp://www.stonybrook.edu/est/people/bios/aszema.shtml


Heart Failure: An Exploration of Recent Advances in Research and Treatment (A).

Szema A, McLarty A, Skopicki H, Bloom M, Jermyn R - Clin Med Insights Cardiol (2015)

anthony.szema@stonybrook.eduhttp://www.stonybrook.edu/est/people/bios/aszema.shtml
© Copyright Policy - open-access
Related In: Results  -  Collection

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getmorefigures.php?uid=PMC4597586&req=5

f1-cmc-suppl.2-2015-053: anthony.szema@stonybrook.eduhttp://www.stonybrook.edu/est/people/bios/aszema.shtml

View Article: PubMed Central - PubMed

Affiliation: Adjunct Professor, College of Engineering and Applied Sciences, Department of Technology and Society, Stony Brook University, Stony Brook, NY, USA. Clinical Assistant Professor, Occupational and Environmental Medicine, Preventive Medicine, and Epidemiology, Department of Population Health, Hofstra North Shore LIJ School of Medicine, Hofstra University, Hempstead, NY, USA.

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

The supplement aims to provide readers with an exploration of recent advances in research on and treatment of heart failure... Common etiological mechanisms of heart failure include coronary ischemia, valvular disease, hypertension, and diastolic dysfunction... Yet, other causes include: post-partum cardiomyopathy, post-infectious, chronic tachycardia, metabolic dysregulation, adverse medication side effects (particularly adriamycin chemotherapy), orphan disease Duchenne’s Muscular Dystrophy, infiltrative diseases (such as amyloidosis), and inflammatory/connective tissue diseases (such as systemic lupus erythematosus)... When known causes of heart failure are excluded then heart failure is classified as idiopathic... Less often studied versus chronic heart failure, is acute decompensated heart failure associated with abrupt-onset symptoms associated with hospitalization... Nearly half of admitted patients with heart failure have preserved ejection fraction., Survival among heart failure patients long-term may be improved with β-blockers, angiotensin converting enzyme inhibitors, aldosterone antagonists, electrophysiology devices such as automatic implantable cardiovascular defibrillators, and vasodilators... Other drugs such as digoxin and diuretics do not alter death rates–digoxin reduces hospitalizations, while diuretics (furosemide or lasix) improve symptoms... Another aspect of heart failure is diastolic dysfunction with preserved left ventricular ejection fraction, accounting for half of hospitalizations... Medications for diastolic dysfunction are similar to systolic dysfunction: ACE inhibitors, ARBs, diuretics, and β-blockers... Dr. McLarty presents a practical review and guideline for LVAD use... Dr. Fahad Gilani et al. discuss “Percutaneous Mechanical Support in Cardiogenic Shock: A Review” and note that mortality is not improved with Intra-Aortic Balloon Pumps (IABP), Extracorporeal Membrane Oxygenation (ECMO) or percutaneous LVADs... Finally, I would like to comment on “Reversible Cardiomyopathies” by Dr. Harsh Patel and co-authors, which reminds us to search the treatable, such as Sympathoexcitation-Induced Takotsubo Cardiomyopathy due to excess catecholamines from autonomic dysfunction... What this may hold for the short-term treatment of heart failure remains to be seen, but ultimately the goal will be to help us improve upon current practice... She now practices as a cardiologist specifically within heart failure and transplant... Dr Jermyn is the author or co-author of 5 published papers and has presented at 3 conferences in the 2014–2015 academic year, including HFSA and ACC.

No MeSH data available.