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AIT (allergen immunotherapy): a model for the "precision medicine".

Passalacqua G, Canonica GW - Clin Mol Allergy (2015)

Bottom Line: The interpretation of medical approaches, especially therapy, evolved rapidly in the last century.Starting from the simple description of symptoms, we moved to the pathophysiological descriptions, to the evidence-based medicine, until the so-called "precision medicine".This latter can be defined as a structural model aimed at customizing healthcare, with medical decisions/products tailored on an individual patient at a highly detailed level.

View Article: PubMed Central - PubMed

Affiliation: Allergy and Respiratory Diseases, Department of Internal Medicine, S. Martino Hospital, IRCCS San Martino-IST-University of Genoa, Pad.Maragliano, L.go R Benzi 10, 16133 Genoa, Italy.

ABSTRACT
The interpretation of medical approaches, especially therapy, evolved rapidly in the last century. Starting from the simple description of symptoms, we moved to the pathophysiological descriptions, to the evidence-based medicine, until the so-called "precision medicine". This latter can be defined as a structural model aimed at customizing healthcare, with medical decisions/products tailored on an individual patient at a highly detailed level. In this sense, allergen immunotherapy represents an optimal model of "precision medicine", since we know and describe symptoms, function, aetiological agents at molecular level, and we have the possibility to intervene on the natural history of the disease. If considered under the point of view of pharmaco-economy, that is prescribing the optimal treatment to the right patient, allergen immunotherapy represents an almost-ideal model of precision medicine.

No MeSH data available.


The role of allergen immunotherapy (AIT) as a personalized or precision medicine
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Fig2: The role of allergen immunotherapy (AIT) as a personalized or precision medicine

Mentions: Under a clinical point of view, AIT is well characterized by numerous clinical trials showing the effectiveness of the treatment [19–21], and this is even more apparent for sublingual immunotherapy (SLIT), for which large trials involving hundreds of patients are nowadays available [21]. According to this, we can perform an optimized prescription (Fig. 2) [17].Fig. 2


AIT (allergen immunotherapy): a model for the "precision medicine".

Passalacqua G, Canonica GW - Clin Mol Allergy (2015)

The role of allergen immunotherapy (AIT) as a personalized or precision medicine
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4597399&req=5

Fig2: The role of allergen immunotherapy (AIT) as a personalized or precision medicine
Mentions: Under a clinical point of view, AIT is well characterized by numerous clinical trials showing the effectiveness of the treatment [19–21], and this is even more apparent for sublingual immunotherapy (SLIT), for which large trials involving hundreds of patients are nowadays available [21]. According to this, we can perform an optimized prescription (Fig. 2) [17].Fig. 2

Bottom Line: The interpretation of medical approaches, especially therapy, evolved rapidly in the last century.Starting from the simple description of symptoms, we moved to the pathophysiological descriptions, to the evidence-based medicine, until the so-called "precision medicine".This latter can be defined as a structural model aimed at customizing healthcare, with medical decisions/products tailored on an individual patient at a highly detailed level.

View Article: PubMed Central - PubMed

Affiliation: Allergy and Respiratory Diseases, Department of Internal Medicine, S. Martino Hospital, IRCCS San Martino-IST-University of Genoa, Pad.Maragliano, L.go R Benzi 10, 16133 Genoa, Italy.

ABSTRACT
The interpretation of medical approaches, especially therapy, evolved rapidly in the last century. Starting from the simple description of symptoms, we moved to the pathophysiological descriptions, to the evidence-based medicine, until the so-called "precision medicine". This latter can be defined as a structural model aimed at customizing healthcare, with medical decisions/products tailored on an individual patient at a highly detailed level. In this sense, allergen immunotherapy represents an optimal model of "precision medicine", since we know and describe symptoms, function, aetiological agents at molecular level, and we have the possibility to intervene on the natural history of the disease. If considered under the point of view of pharmaco-economy, that is prescribing the optimal treatment to the right patient, allergen immunotherapy represents an almost-ideal model of precision medicine.

No MeSH data available.