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High levels of contamination and antimicrobial-resistant non-typhoidal Salmonella serovars on pig and poultry farms in the Mekong Delta of Vietnam.

Tu LT, Hoang NV, Cuong NV, Campbell J, Bryant JE, Hoa NT, Kiet BT, Thompson C, Duy DT, Phat VV, Hien VB, Thwaites G, Baker S, Carrique-Mas JJ - Epidemiol. Infect. (2015)

Bottom Line: Factors independently associated with NTS were duck farms [odds ratio (OR) 21·2], farm with >50 pigs (OR 11·9), pig farm with 5-50 pigs (OR 4·88) (vs. chickens), and frequent rodent sightings (OR 2·3).Both S.Multidrug resistance (resistance against ⩾3 classes of antimicrobial) was independently associated with monophasic S.

View Article: PubMed Central - PubMed

Affiliation: Hospital for Tropical Diseases,Wellcome Trust Major Overseas Programme,Oxford University Clinical Research Unit,Ho Chi Minh City,Vietnam.

ABSTRACT
We investigated the prevalence, diversity, and antimicrobial resistance (AMR) profiles of non-typhoidal Salmonella (NTS) and associated risk factors on 341 pig, chicken, and duck farms in Dong Thap province (Mekong Delta, Vietnam). Sampling was stratified by species, district (four categories), and farm size (three categories). Pooled faeces, collected using boot swabs, were tested using ISO 6575: 2002 (Annex D). Isolates were serogrouped; group B isolates were tested by polymerase chain reaction to detect S. Typhimurium and (monophasic) serovar 4,[5],12:i:- variants. The farm-level adjusted NTS prevalence was 64·7%, 94·3% and 91·3% for chicken, duck and pig farms, respectively. Factors independently associated with NTS were duck farms [odds ratio (OR) 21·2], farm with >50 pigs (OR 11·9), pig farm with 5-50 pigs (OR 4·88) (vs. chickens), and frequent rodent sightings (OR 2·3). Both S. Typhimurium and monophasic S. Typhimurium were more common in duck farms. Isolates had a high prevalence of resistance (77·6%) against tetracycline, moderate resistance (20-30%) against chloramphenicol, sulfamethoxazole-trimethoprim, ampicillin and nalidixic acid, and low resistance (<5%) against ciprofloxacin and third-generation cephalosporins. Multidrug resistance (resistance against ⩾3 classes of antimicrobial) was independently associated with monophasic S. Typhimurium and other group B isolates (excluding S. Typhimurium) and pig farms. The unusually high prevalence of NTS on Mekong Delta farms poses formidable challenges for control.

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Distribution of farms by number of boot swabs positive for non-typhoidalSalmonella, presented separately by host species and size (DongThap, Mekong Delta, 2012).
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fig02: Distribution of farms by number of boot swabs positive for non-typhoidalSalmonella, presented separately by host species and size (DongThap, Mekong Delta, 2012).

Mentions: At the sample (swab) level, the highest prevalence of NTS corresponded to samples fromduck farms (69·8%, 95% CI 61·2–76·3), followed by pig (65·4%, 95% CI 59·0–71·9) andchicken (31·0%, 95% CI 22·3–39·3) farms (Fig. 2).Fig. 2.


High levels of contamination and antimicrobial-resistant non-typhoidal Salmonella serovars on pig and poultry farms in the Mekong Delta of Vietnam.

Tu LT, Hoang NV, Cuong NV, Campbell J, Bryant JE, Hoa NT, Kiet BT, Thompson C, Duy DT, Phat VV, Hien VB, Thwaites G, Baker S, Carrique-Mas JJ - Epidemiol. Infect. (2015)

Distribution of farms by number of boot swabs positive for non-typhoidalSalmonella, presented separately by host species and size (DongThap, Mekong Delta, 2012).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4595858&req=5

fig02: Distribution of farms by number of boot swabs positive for non-typhoidalSalmonella, presented separately by host species and size (DongThap, Mekong Delta, 2012).
Mentions: At the sample (swab) level, the highest prevalence of NTS corresponded to samples fromduck farms (69·8%, 95% CI 61·2–76·3), followed by pig (65·4%, 95% CI 59·0–71·9) andchicken (31·0%, 95% CI 22·3–39·3) farms (Fig. 2).Fig. 2.

Bottom Line: Factors independently associated with NTS were duck farms [odds ratio (OR) 21·2], farm with >50 pigs (OR 11·9), pig farm with 5-50 pigs (OR 4·88) (vs. chickens), and frequent rodent sightings (OR 2·3).Both S.Multidrug resistance (resistance against ⩾3 classes of antimicrobial) was independently associated with monophasic S.

View Article: PubMed Central - PubMed

Affiliation: Hospital for Tropical Diseases,Wellcome Trust Major Overseas Programme,Oxford University Clinical Research Unit,Ho Chi Minh City,Vietnam.

ABSTRACT
We investigated the prevalence, diversity, and antimicrobial resistance (AMR) profiles of non-typhoidal Salmonella (NTS) and associated risk factors on 341 pig, chicken, and duck farms in Dong Thap province (Mekong Delta, Vietnam). Sampling was stratified by species, district (four categories), and farm size (three categories). Pooled faeces, collected using boot swabs, were tested using ISO 6575: 2002 (Annex D). Isolates were serogrouped; group B isolates were tested by polymerase chain reaction to detect S. Typhimurium and (monophasic) serovar 4,[5],12:i:- variants. The farm-level adjusted NTS prevalence was 64·7%, 94·3% and 91·3% for chicken, duck and pig farms, respectively. Factors independently associated with NTS were duck farms [odds ratio (OR) 21·2], farm with >50 pigs (OR 11·9), pig farm with 5-50 pigs (OR 4·88) (vs. chickens), and frequent rodent sightings (OR 2·3). Both S. Typhimurium and monophasic S. Typhimurium were more common in duck farms. Isolates had a high prevalence of resistance (77·6%) against tetracycline, moderate resistance (20-30%) against chloramphenicol, sulfamethoxazole-trimethoprim, ampicillin and nalidixic acid, and low resistance (<5%) against ciprofloxacin and third-generation cephalosporins. Multidrug resistance (resistance against ⩾3 classes of antimicrobial) was independently associated with monophasic S. Typhimurium and other group B isolates (excluding S. Typhimurium) and pig farms. The unusually high prevalence of NTS on Mekong Delta farms poses formidable challenges for control.

Show MeSH
Related in: MedlinePlus