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Age-specific differences in influenza virus type and subtype distribution in the 2012/2013 season in 12 European countries.

Beauté J, Zucs P, Korsun N, Bragstad K, Enouf V, Kossyvakis A, Griškevičius A, Olinger CM, Meijer A, Guiomar R, Prosenc K, Staroňová E, Delgado C, Brytting M, Broberg E, European Influenza Surveillance Netwo - Epidemiol. Infect. (2015)

Bottom Line: The analysis by age group suggests that the overall distribution of circulating (sub)types may mask substantial differences between age groups.This means that the intepretation of syndromic surveillance data without age group-specific virological data may be misleading.Surveillance at the European level would benefit from the reporting of age-specific influenza data.

View Article: PubMed Central - PubMed

Affiliation: European Centre for Disease Prevention and Control (ECDC),Solna,Sweden.

ABSTRACT
The epidemiology of seasonal influenza is influenced by age. During the influenza season, the European Influenza Surveillance Network (EISN) reports weekly virological and syndromic surveillance data [mostly influenza-like illness (ILI)] based on national networks of sentinel primary-care providers. Aggregated numbers by age group are available for ILI, but not linked to the virological data. At the end of the influenza season 2012/2013, all EISN laboratories were invited to submit a subset of their virological data for this season, including information on age. The analysis by age group suggests that the overall distribution of circulating (sub)types may mask substantial differences between age groups. Thus, in cases aged 5-14 years, 75% tested positive for influenza B virus whereas all other age groups had an even distribution of influenza A and B viruses. This means that the intepretation of syndromic surveillance data without age group-specific virological data may be misleading. Surveillance at the European level would benefit from the reporting of age-specific influenza data.

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Influenza virus type and subtype distribution by age group, 12 European Union countries, influenza season 2012/2013.
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fig02: Influenza virus type and subtype distribution by age group, 12 European Union countries, influenza season 2012/2013.

Mentions: Of the 7849 positive specimens reported with information on age, 1227 (16%) were from the 0–4 years age group, 2161 (28%) from 5–14 years, 4067 (52%) from 15–64 years and 394 (5%) from cases aged ⩾65 years. In cases aged 5–14 years, 75% tested positive for influenza B virus whereas all other age groups had an even distribution of influenza A and B viruses (Fig. 2). Of the influenza A viruses subtyped, A(H1)pdm09 viruses dominated over A(H3) viruses in all cases up to age 64 years (68% vs. 32% overall) whereas in those aged ⩾65 years, A(H3) viruses dominated (65% vs. 35%). Overall, the distribution of the virus types and subtypes were significantly different in age groups (P < 0·0001).Fig. 2.


Age-specific differences in influenza virus type and subtype distribution in the 2012/2013 season in 12 European countries.

Beauté J, Zucs P, Korsun N, Bragstad K, Enouf V, Kossyvakis A, Griškevičius A, Olinger CM, Meijer A, Guiomar R, Prosenc K, Staroňová E, Delgado C, Brytting M, Broberg E, European Influenza Surveillance Netwo - Epidemiol. Infect. (2015)

Influenza virus type and subtype distribution by age group, 12 European Union countries, influenza season 2012/2013.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4595855&req=5

fig02: Influenza virus type and subtype distribution by age group, 12 European Union countries, influenza season 2012/2013.
Mentions: Of the 7849 positive specimens reported with information on age, 1227 (16%) were from the 0–4 years age group, 2161 (28%) from 5–14 years, 4067 (52%) from 15–64 years and 394 (5%) from cases aged ⩾65 years. In cases aged 5–14 years, 75% tested positive for influenza B virus whereas all other age groups had an even distribution of influenza A and B viruses (Fig. 2). Of the influenza A viruses subtyped, A(H1)pdm09 viruses dominated over A(H3) viruses in all cases up to age 64 years (68% vs. 32% overall) whereas in those aged ⩾65 years, A(H3) viruses dominated (65% vs. 35%). Overall, the distribution of the virus types and subtypes were significantly different in age groups (P < 0·0001).Fig. 2.

Bottom Line: The analysis by age group suggests that the overall distribution of circulating (sub)types may mask substantial differences between age groups.This means that the intepretation of syndromic surveillance data without age group-specific virological data may be misleading.Surveillance at the European level would benefit from the reporting of age-specific influenza data.

View Article: PubMed Central - PubMed

Affiliation: European Centre for Disease Prevention and Control (ECDC),Solna,Sweden.

ABSTRACT
The epidemiology of seasonal influenza is influenced by age. During the influenza season, the European Influenza Surveillance Network (EISN) reports weekly virological and syndromic surveillance data [mostly influenza-like illness (ILI)] based on national networks of sentinel primary-care providers. Aggregated numbers by age group are available for ILI, but not linked to the virological data. At the end of the influenza season 2012/2013, all EISN laboratories were invited to submit a subset of their virological data for this season, including information on age. The analysis by age group suggests that the overall distribution of circulating (sub)types may mask substantial differences between age groups. Thus, in cases aged 5-14 years, 75% tested positive for influenza B virus whereas all other age groups had an even distribution of influenza A and B viruses. This means that the intepretation of syndromic surveillance data without age group-specific virological data may be misleading. Surveillance at the European level would benefit from the reporting of age-specific influenza data.

Show MeSH
Related in: MedlinePlus