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Six-month quality-of-life and functional status of acute respiratory distress syndrome survivors compared to patients at risk: a population-based study.

Biehl M, Kashyap R, Ahmed AH, Reriani MK, Ofoma UR, Wilson GA, Li G, Malinchoc M, Sloan JA, Gajic O - Crit Care (2015)

Bottom Line: The primary outcomes were changes in QOL and functional status, measured through 12-Item Short Form Survey (SF-12) and Barthel Index (BI) respectively, from baseline to 6 months, compared between survivors who did and did not develop ARDS.Both ARDS and non-ARDS groups had lower physical component of SF-12 at baseline compared to general population (P < 0.001 for both).In this population-based study, decreased QOL and functional status 6 months after hospitalization were largely explained by baseline condition, with similar recovery in survivors who did and did not develop ARDS.

View Article: PubMed Central - PubMed

Affiliation: Multidisciplinary Epidemiology and Translational Research in Intensive Care (METRIC) Group, Mayo Clinic, Rochester, MN, USA. mibiehl@yahoo.com.br.

ABSTRACT

Introduction: The long-term attributable burden related to acute respiratory distress syndrome (ARDS) is not fully investigated. The aim of this study is to evaluate the quality of life (QOL) and functional status at 6 months after hospitalization in patients at risk for ARDS who did and did not develop the syndrome.

Method: This is a population-based prospective cohort study of adult patients from Olmsted County, Minnesota, with or at risk for ARDS hospitalized from October 2008 to July 2011. The primary outcomes were changes in QOL and functional status, measured through 12-Item Short Form Survey (SF-12) and Barthel Index (BI) respectively, from baseline to 6 months, compared between survivors who did and did not develop ARDS.

Results: Of 410 patients with or at risk for ARDS, 98 had baseline surveys collected and 67 responded to a 6-month survey (26 ARDS, 41 non-ARDS). Both ARDS and non-ARDS groups had lower physical component of SF-12 at baseline compared to general population (P < 0.001 for both). ARDS patients had poorer baseline functional status compared to non-ARDS (mean BI 80 ± 25 vs. 88 ± 22, P = 0.03). No significant differences were observed for the change between 6 months and baseline BI (delta 2.3 for ARDS vs. 2.0 for non-ARDS, P = 0.5), or mental (delta 2.7 vs. 2.4, P = 0.9) or physical (delta -3 vs. -3.3, P = 0.9) component of SF-12 between survivors with and without ARDS.

Conclusion: In this population-based study, decreased QOL and functional status 6 months after hospitalization were largely explained by baseline condition, with similar recovery in survivors who did and did not develop ARDS.

No MeSH data available.


Related in: MedlinePlus

Consolidated Standards of Reporting Trials (CONSORT) flowchart diagram. ARDS acute respiratory distress syndrome
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Fig1: Consolidated Standards of Reporting Trials (CONSORT) flowchart diagram. ARDS acute respiratory distress syndrome

Mentions: Of 410 patients who were identified with ARDS or at risk of ARDS at the time of hospital admission during the 3-year study period (2008 − 2011), 98 had baseline surveys collected (Consolidated Standards of Reporting Trials (CONSORT) flowchart diagram, Fig. 1). Eligible patients who did and did not complete the baseline survey had similar sex, race, ARDS status and Charlson comorbidity index (Additional file 1: Online Resource 1). Patients who did not complete the baseline survey were older (67 vs. 62 years), had a higher APACHE III score (80 vs. 71), were more often treated in the ICU (68 vs. 54 %), and had higher mortality (Additional file 1: Online Resource 1).Fig. 1


Six-month quality-of-life and functional status of acute respiratory distress syndrome survivors compared to patients at risk: a population-based study.

Biehl M, Kashyap R, Ahmed AH, Reriani MK, Ofoma UR, Wilson GA, Li G, Malinchoc M, Sloan JA, Gajic O - Crit Care (2015)

Consolidated Standards of Reporting Trials (CONSORT) flowchart diagram. ARDS acute respiratory distress syndrome
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4591714&req=5

Fig1: Consolidated Standards of Reporting Trials (CONSORT) flowchart diagram. ARDS acute respiratory distress syndrome
Mentions: Of 410 patients who were identified with ARDS or at risk of ARDS at the time of hospital admission during the 3-year study period (2008 − 2011), 98 had baseline surveys collected (Consolidated Standards of Reporting Trials (CONSORT) flowchart diagram, Fig. 1). Eligible patients who did and did not complete the baseline survey had similar sex, race, ARDS status and Charlson comorbidity index (Additional file 1: Online Resource 1). Patients who did not complete the baseline survey were older (67 vs. 62 years), had a higher APACHE III score (80 vs. 71), were more often treated in the ICU (68 vs. 54 %), and had higher mortality (Additional file 1: Online Resource 1).Fig. 1

Bottom Line: The primary outcomes were changes in QOL and functional status, measured through 12-Item Short Form Survey (SF-12) and Barthel Index (BI) respectively, from baseline to 6 months, compared between survivors who did and did not develop ARDS.Both ARDS and non-ARDS groups had lower physical component of SF-12 at baseline compared to general population (P < 0.001 for both).In this population-based study, decreased QOL and functional status 6 months after hospitalization were largely explained by baseline condition, with similar recovery in survivors who did and did not develop ARDS.

View Article: PubMed Central - PubMed

Affiliation: Multidisciplinary Epidemiology and Translational Research in Intensive Care (METRIC) Group, Mayo Clinic, Rochester, MN, USA. mibiehl@yahoo.com.br.

ABSTRACT

Introduction: The long-term attributable burden related to acute respiratory distress syndrome (ARDS) is not fully investigated. The aim of this study is to evaluate the quality of life (QOL) and functional status at 6 months after hospitalization in patients at risk for ARDS who did and did not develop the syndrome.

Method: This is a population-based prospective cohort study of adult patients from Olmsted County, Minnesota, with or at risk for ARDS hospitalized from October 2008 to July 2011. The primary outcomes were changes in QOL and functional status, measured through 12-Item Short Form Survey (SF-12) and Barthel Index (BI) respectively, from baseline to 6 months, compared between survivors who did and did not develop ARDS.

Results: Of 410 patients with or at risk for ARDS, 98 had baseline surveys collected and 67 responded to a 6-month survey (26 ARDS, 41 non-ARDS). Both ARDS and non-ARDS groups had lower physical component of SF-12 at baseline compared to general population (P < 0.001 for both). ARDS patients had poorer baseline functional status compared to non-ARDS (mean BI 80 ± 25 vs. 88 ± 22, P = 0.03). No significant differences were observed for the change between 6 months and baseline BI (delta 2.3 for ARDS vs. 2.0 for non-ARDS, P = 0.5), or mental (delta 2.7 vs. 2.4, P = 0.9) or physical (delta -3 vs. -3.3, P = 0.9) component of SF-12 between survivors with and without ARDS.

Conclusion: In this population-based study, decreased QOL and functional status 6 months after hospitalization were largely explained by baseline condition, with similar recovery in survivors who did and did not develop ARDS.

No MeSH data available.


Related in: MedlinePlus