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Incidence of HIV and Syphilis among Men Who Have Sex with Men (MSM) in Beijing: An Open Cohort Study.

Liu G, Lu H, Wang J, Xia D, Sun Y, Mi G, Wang L - PLoS ONE (2015)

Bottom Line: Variables which corresponded to increased loss to follow-up included younger age, less education, non-identification of homosexual identity, and migrant status.The predictors for the high HIV incidence included unsafe anal sex, sex after drinking alcohol and STI infection.More research is needed to provide multi-pronged HIV prevention interventions among MSM in order to reduce the increasing burden of HIV and sexually transmitted infections (STIs) in China.

View Article: PubMed Central - PubMed

Affiliation: Beijing Municipality Center for Disease Control and Prevention, Beijing, China.

ABSTRACT

Background: This study investigated HIV and syphilis incidence among men who have sex with men (MSM) in Beijing, China.

Methods: An open cohort was established from September 2009 to April 2012. Participants were followed up with every three to four months after recruitment and for thirty-one months in total. Chi-square tests were used to compare demographic and behavioral characteristics between participants who were followed up with and those lost to follow up. Univariate and multivariate Cox proportional hazards regression analyses were used to examine demographic and behavioral associations with HIV and syphilis incidence.

Results: 69.7% (699/1,003) of the participants finished at least two follow-up surveys during the study period. Variables which corresponded to increased loss to follow-up included younger age, less education, non-identification of homosexual identity, and migrant status. A total of 1,045 person-years (PYs) and 1,016.4 PYs were followed up for HIV and syphilis incidence estimation, respectively. The HIV incidence was 5.9 per 100 PYs and 7.8 per 100 PYs for syphilis. The predictors for the high HIV incidence included unsafe anal sex, sex after drinking alcohol and STI infection.

Conclusion: HIV incidence increased rapidly within the cohort, but syphilis incidence remained stable and decreased. More research is needed to provide multi-pronged HIV prevention interventions among MSM in order to reduce the increasing burden of HIV and sexually transmitted infections (STIs) in China.

No MeSH data available.


Related in: MedlinePlus

Participation of eligible men who have sex with mem in the open cohort study in Beijing, 2009–2012.
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pone.0138232.g002: Participation of eligible men who have sex with mem in the open cohort study in Beijing, 2009–2012.

Mentions: During the study period, 1,041 MSM were surveyed, among whom 1,003 baseline HIV- negative MSM were recruited in the open cohort. 612 participants were recruited through RDS, while 220 and 171 from the second and third round were recruited from the VCT site mentioned above. In total, eight sessions of follow up visits were conducted. Among 1,003 participants, 218 completed all eight follow up visits. 699 finished at least two surveys during the study period. These 699 participants were included in the final data analysis for incidence estimation. 304 participants were lost-to-follow-up. Fig 2 shows the participation of subjects in our study at baseline and at each follow-up visit.


Incidence of HIV and Syphilis among Men Who Have Sex with Men (MSM) in Beijing: An Open Cohort Study.

Liu G, Lu H, Wang J, Xia D, Sun Y, Mi G, Wang L - PLoS ONE (2015)

Participation of eligible men who have sex with mem in the open cohort study in Beijing, 2009–2012.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4591335&req=5

pone.0138232.g002: Participation of eligible men who have sex with mem in the open cohort study in Beijing, 2009–2012.
Mentions: During the study period, 1,041 MSM were surveyed, among whom 1,003 baseline HIV- negative MSM were recruited in the open cohort. 612 participants were recruited through RDS, while 220 and 171 from the second and third round were recruited from the VCT site mentioned above. In total, eight sessions of follow up visits were conducted. Among 1,003 participants, 218 completed all eight follow up visits. 699 finished at least two surveys during the study period. These 699 participants were included in the final data analysis for incidence estimation. 304 participants were lost-to-follow-up. Fig 2 shows the participation of subjects in our study at baseline and at each follow-up visit.

Bottom Line: Variables which corresponded to increased loss to follow-up included younger age, less education, non-identification of homosexual identity, and migrant status.The predictors for the high HIV incidence included unsafe anal sex, sex after drinking alcohol and STI infection.More research is needed to provide multi-pronged HIV prevention interventions among MSM in order to reduce the increasing burden of HIV and sexually transmitted infections (STIs) in China.

View Article: PubMed Central - PubMed

Affiliation: Beijing Municipality Center for Disease Control and Prevention, Beijing, China.

ABSTRACT

Background: This study investigated HIV and syphilis incidence among men who have sex with men (MSM) in Beijing, China.

Methods: An open cohort was established from September 2009 to April 2012. Participants were followed up with every three to four months after recruitment and for thirty-one months in total. Chi-square tests were used to compare demographic and behavioral characteristics between participants who were followed up with and those lost to follow up. Univariate and multivariate Cox proportional hazards regression analyses were used to examine demographic and behavioral associations with HIV and syphilis incidence.

Results: 69.7% (699/1,003) of the participants finished at least two follow-up surveys during the study period. Variables which corresponded to increased loss to follow-up included younger age, less education, non-identification of homosexual identity, and migrant status. A total of 1,045 person-years (PYs) and 1,016.4 PYs were followed up for HIV and syphilis incidence estimation, respectively. The HIV incidence was 5.9 per 100 PYs and 7.8 per 100 PYs for syphilis. The predictors for the high HIV incidence included unsafe anal sex, sex after drinking alcohol and STI infection.

Conclusion: HIV incidence increased rapidly within the cohort, but syphilis incidence remained stable and decreased. More research is needed to provide multi-pronged HIV prevention interventions among MSM in order to reduce the increasing burden of HIV and sexually transmitted infections (STIs) in China.

No MeSH data available.


Related in: MedlinePlus