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The first case of feline sinonasal aspergillosis due to Aspergillus fischeri in Japan.

Kano R, Takahashi T, Hayakawa T, Yamaya Y, Hasegawa A, Kamata H - J. Vet. Med. Sci. (2015)

Bottom Line: The patient presented after 2 months of progressive facial deformity around the nose and nasal discharge.The isolate from this case was susceptible to itraconazole (ITZ), voriconazole and micafungin, but was resistant to amphotericine B.However, the infected cat died approximately 1 month after referral, despite treatment for 12 days ITZ administered orally at 10 mg/kg.

View Article: PubMed Central - PubMed

Affiliation: Veterinary Pathobiology, Nihon University College of Bioresource Sciences, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan.

ABSTRACT
Feline upper respiratory tract infection due to Aspergillus spp. is considered an emerging disease, with the number of reported cases continuing to rise. In this study, we report the first case of feline sinonasal aspergillosis caused by Aspergillus fischeri in Japan. The patient presented after 2 months of progressive facial deformity around the nose and nasal discharge. The isolate from this case was susceptible to itraconazole (ITZ), voriconazole and micafungin, but was resistant to amphotericine B. However, the infected cat died approximately 1 month after referral, despite treatment for 12 days ITZ administered orally at 10 mg/kg.

No MeSH data available.


Related in: MedlinePlus

Histopathologic examination of the mass from the right nasal cavity of the caserevealed chronic purulent inflammation with many branching hyphal filaments (HEstain).
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fig_003: Histopathologic examination of the mass from the right nasal cavity of the caserevealed chronic purulent inflammation with many branching hyphal filaments (HEstain).

Mentions: The left panel shows a computed tomographic (CT) image after administration of acontrast agent at the level of the canine teeth. The animal’s right nasal cavity (R)is occupied by a large mass (*) that lacks contrast enhancement. The right panel showsa reconstructed image from multiple CT images of the head; the right side of the nasalbone is largely destroyed.


The first case of feline sinonasal aspergillosis due to Aspergillus fischeri in Japan.

Kano R, Takahashi T, Hayakawa T, Yamaya Y, Hasegawa A, Kamata H - J. Vet. Med. Sci. (2015)

Histopathologic examination of the mass from the right nasal cavity of the caserevealed chronic purulent inflammation with many branching hyphal filaments (HEstain).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4591165&req=5

fig_003: Histopathologic examination of the mass from the right nasal cavity of the caserevealed chronic purulent inflammation with many branching hyphal filaments (HEstain).
Mentions: The left panel shows a computed tomographic (CT) image after administration of acontrast agent at the level of the canine teeth. The animal’s right nasal cavity (R)is occupied by a large mass (*) that lacks contrast enhancement. The right panel showsa reconstructed image from multiple CT images of the head; the right side of the nasalbone is largely destroyed.

Bottom Line: The patient presented after 2 months of progressive facial deformity around the nose and nasal discharge.The isolate from this case was susceptible to itraconazole (ITZ), voriconazole and micafungin, but was resistant to amphotericine B.However, the infected cat died approximately 1 month after referral, despite treatment for 12 days ITZ administered orally at 10 mg/kg.

View Article: PubMed Central - PubMed

Affiliation: Veterinary Pathobiology, Nihon University College of Bioresource Sciences, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan.

ABSTRACT
Feline upper respiratory tract infection due to Aspergillus spp. is considered an emerging disease, with the number of reported cases continuing to rise. In this study, we report the first case of feline sinonasal aspergillosis caused by Aspergillus fischeri in Japan. The patient presented after 2 months of progressive facial deformity around the nose and nasal discharge. The isolate from this case was susceptible to itraconazole (ITZ), voriconazole and micafungin, but was resistant to amphotericine B. However, the infected cat died approximately 1 month after referral, despite treatment for 12 days ITZ administered orally at 10 mg/kg.

No MeSH data available.


Related in: MedlinePlus