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The first case of feline sinonasal aspergillosis due to Aspergillus fischeri in Japan.

Kano R, Takahashi T, Hayakawa T, Yamaya Y, Hasegawa A, Kamata H - J. Vet. Med. Sci. (2015)

Bottom Line: The patient presented after 2 months of progressive facial deformity around the nose and nasal discharge.The isolate from this case was susceptible to itraconazole (ITZ), voriconazole and micafungin, but was resistant to amphotericine B.However, the infected cat died approximately 1 month after referral, despite treatment for 12 days ITZ administered orally at 10 mg/kg.

View Article: PubMed Central - PubMed

Affiliation: Veterinary Pathobiology, Nihon University College of Bioresource Sciences, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan.

ABSTRACT
Feline upper respiratory tract infection due to Aspergillus spp. is considered an emerging disease, with the number of reported cases continuing to rise. In this study, we report the first case of feline sinonasal aspergillosis caused by Aspergillus fischeri in Japan. The patient presented after 2 months of progressive facial deformity around the nose and nasal discharge. The isolate from this case was susceptible to itraconazole (ITZ), voriconazole and micafungin, but was resistant to amphotericine B. However, the infected cat died approximately 1 month after referral, despite treatment for 12 days ITZ administered orally at 10 mg/kg.

No MeSH data available.


Related in: MedlinePlus

Pus discharge and an ulcer were observed on the mass on the left side of the bridge ofthe nose.
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fig_001: Pus discharge and an ulcer were observed on the mass on the left side of the bridge ofthe nose.

Mentions: Case: A castrated Russian blue cat (11 years old; weight, 2.9 kg) wasreferred to the Nihon University Animal Medical Center, Kanagawa, Japan, in June 2014 afterexhibited progressive facial deformity around the nose with nasal discharge over the previous2 months. The cat suffered from diabetes mellitus and had been treated with insulin for 5years. However, control by insulin injection was not succeesful in the patient cat. Physicalexamination of the cat showed swelling on the nose (Fig.1Fig. 1.


The first case of feline sinonasal aspergillosis due to Aspergillus fischeri in Japan.

Kano R, Takahashi T, Hayakawa T, Yamaya Y, Hasegawa A, Kamata H - J. Vet. Med. Sci. (2015)

Pus discharge and an ulcer were observed on the mass on the left side of the bridge ofthe nose.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4591165&req=5

fig_001: Pus discharge and an ulcer were observed on the mass on the left side of the bridge ofthe nose.
Mentions: Case: A castrated Russian blue cat (11 years old; weight, 2.9 kg) wasreferred to the Nihon University Animal Medical Center, Kanagawa, Japan, in June 2014 afterexhibited progressive facial deformity around the nose with nasal discharge over the previous2 months. The cat suffered from diabetes mellitus and had been treated with insulin for 5years. However, control by insulin injection was not succeesful in the patient cat. Physicalexamination of the cat showed swelling on the nose (Fig.1Fig. 1.

Bottom Line: The patient presented after 2 months of progressive facial deformity around the nose and nasal discharge.The isolate from this case was susceptible to itraconazole (ITZ), voriconazole and micafungin, but was resistant to amphotericine B.However, the infected cat died approximately 1 month after referral, despite treatment for 12 days ITZ administered orally at 10 mg/kg.

View Article: PubMed Central - PubMed

Affiliation: Veterinary Pathobiology, Nihon University College of Bioresource Sciences, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan.

ABSTRACT
Feline upper respiratory tract infection due to Aspergillus spp. is considered an emerging disease, with the number of reported cases continuing to rise. In this study, we report the first case of feline sinonasal aspergillosis caused by Aspergillus fischeri in Japan. The patient presented after 2 months of progressive facial deformity around the nose and nasal discharge. The isolate from this case was susceptible to itraconazole (ITZ), voriconazole and micafungin, but was resistant to amphotericine B. However, the infected cat died approximately 1 month after referral, despite treatment for 12 days ITZ administered orally at 10 mg/kg.

No MeSH data available.


Related in: MedlinePlus