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Lipoprotein cholesterol and triglyceride concentrations associated with dog body condition score; effect of recommended fasting duration on sample concentrations in Japanese private clinics.

Usui S, Yasuda H, Koketsu Y - J. Vet. Med. Sci. (2015)

Bottom Line: Two-level linear mixed-effects models were applied to the data.Across all BCS, as dog age rose from 0 to 8 years old, HDL cholesterol concentrations decreased by 13.5 mg/dl, whereas VLDL triglyceride concentrations increased by 81.7 mg/dl (P<0.05).In conclusion, FD of 8 hr or less may affect lipoprotein lipid concentrations.

View Article: PubMed Central - PubMed

Affiliation: School of Agriculture, Meiji University, 1-1-1 Higashi-mita, Tama-ku, Kawasaki, Kanagawa 214-8571, Japan.

ABSTRACT
The objectives of this study were to survey clinics' guidance about recommended fasting duration (FD) prior to lipoprotein analysis, and to characterize lipoprotein cholesterol and triglyceride concentrations in obese and overweight dogs categorized on the basis of the 5-point body condition score (BCS) scale. A dataset was created from lipoprotein analysis medical records of 1,538 dogs from 75 breeds in 354 clinics from 2012 to 2013. A phone survey was conducted to obtain the clinics' FD. Two-level linear mixed-effects models were applied to the data. Over 50% of the clinics said they recommended fasting for 12 hr or more. Dogs in clinics with FD 12 hr or more had lower chylomicron triglyceride concentrations than those in clinics with FD less than 8 hr (P=0.05). Mean (± SEM) BCS at sampling was 3.7 ± 0.02. Obese and overweight dogs had higher very low density lipoprotein (VLDL) and high density lipoprotein (HDL) cholesterol and triglyceride concentrations than ideal dogs (P<0.05), but no such difference was found for low density lipoprotein cholesterol and triglyceride concentrations (P≥0.07). Across all BCS, as dog age rose from 0 to 8 years old, HDL cholesterol concentrations decreased by 13.5 mg/dl, whereas VLDL triglyceride concentrations increased by 81.7 mg/dl (P<0.05). In conclusion, FD of 8 hr or less may affect lipoprotein lipid concentrations. Obese and overweight dogs were characterized as having high VLDL and HDL cholesterol and triglyceride concentrations.

No MeSH data available.


Related in: MedlinePlus

Estimated cholesterol (A) and triglyceride (B) concentrations(mg/dl) in 4 lipoprotein classes* of dogs at different ages. *The 4lipoprotein classes were chylomicrons (CM), very low density lipoproteins (VLDL), lowdensity lipoproteins (LDL) and high density lipoproteins (HDL).
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fig_001: Estimated cholesterol (A) and triglyceride (B) concentrations(mg/dl) in 4 lipoprotein classes* of dogs at different ages. *The 4lipoprotein classes were chylomicrons (CM), very low density lipoproteins (VLDL), lowdensity lipoproteins (LDL) and high density lipoproteins (HDL).

Mentions: Cholesterol and triglyceride concentrations in the four lipoprotein classes were associatedwith increased age (P<0.05; Tables3 and 4). The HDL and LDL cholesterolconcentrations decreased respectively from 203.9 mg/dl to 190.4mg/dl and from 60.1 mg/dl to 40.0 mg/dlas the dog age rose from 0 to 8 and 7 years old, and then, both concentrations rose again asage increased further (P<0.05; Fig.1AFig. 1.


Lipoprotein cholesterol and triglyceride concentrations associated with dog body condition score; effect of recommended fasting duration on sample concentrations in Japanese private clinics.

Usui S, Yasuda H, Koketsu Y - J. Vet. Med. Sci. (2015)

Estimated cholesterol (A) and triglyceride (B) concentrations(mg/dl) in 4 lipoprotein classes* of dogs at different ages. *The 4lipoprotein classes were chylomicrons (CM), very low density lipoproteins (VLDL), lowdensity lipoproteins (LDL) and high density lipoproteins (HDL).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4591146&req=5

fig_001: Estimated cholesterol (A) and triglyceride (B) concentrations(mg/dl) in 4 lipoprotein classes* of dogs at different ages. *The 4lipoprotein classes were chylomicrons (CM), very low density lipoproteins (VLDL), lowdensity lipoproteins (LDL) and high density lipoproteins (HDL).
Mentions: Cholesterol and triglyceride concentrations in the four lipoprotein classes were associatedwith increased age (P<0.05; Tables3 and 4). The HDL and LDL cholesterolconcentrations decreased respectively from 203.9 mg/dl to 190.4mg/dl and from 60.1 mg/dl to 40.0 mg/dlas the dog age rose from 0 to 8 and 7 years old, and then, both concentrations rose again asage increased further (P<0.05; Fig.1AFig. 1.

Bottom Line: Two-level linear mixed-effects models were applied to the data.Across all BCS, as dog age rose from 0 to 8 years old, HDL cholesterol concentrations decreased by 13.5 mg/dl, whereas VLDL triglyceride concentrations increased by 81.7 mg/dl (P<0.05).In conclusion, FD of 8 hr or less may affect lipoprotein lipid concentrations.

View Article: PubMed Central - PubMed

Affiliation: School of Agriculture, Meiji University, 1-1-1 Higashi-mita, Tama-ku, Kawasaki, Kanagawa 214-8571, Japan.

ABSTRACT
The objectives of this study were to survey clinics' guidance about recommended fasting duration (FD) prior to lipoprotein analysis, and to characterize lipoprotein cholesterol and triglyceride concentrations in obese and overweight dogs categorized on the basis of the 5-point body condition score (BCS) scale. A dataset was created from lipoprotein analysis medical records of 1,538 dogs from 75 breeds in 354 clinics from 2012 to 2013. A phone survey was conducted to obtain the clinics' FD. Two-level linear mixed-effects models were applied to the data. Over 50% of the clinics said they recommended fasting for 12 hr or more. Dogs in clinics with FD 12 hr or more had lower chylomicron triglyceride concentrations than those in clinics with FD less than 8 hr (P=0.05). Mean (± SEM) BCS at sampling was 3.7 ± 0.02. Obese and overweight dogs had higher very low density lipoprotein (VLDL) and high density lipoprotein (HDL) cholesterol and triglyceride concentrations than ideal dogs (P<0.05), but no such difference was found for low density lipoprotein cholesterol and triglyceride concentrations (P≥0.07). Across all BCS, as dog age rose from 0 to 8 years old, HDL cholesterol concentrations decreased by 13.5 mg/dl, whereas VLDL triglyceride concentrations increased by 81.7 mg/dl (P<0.05). In conclusion, FD of 8 hr or less may affect lipoprotein lipid concentrations. Obese and overweight dogs were characterized as having high VLDL and HDL cholesterol and triglyceride concentrations.

No MeSH data available.


Related in: MedlinePlus