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Hypertensive Crisis, Burden, Management, and Outcome at a Tertiary Care Center in Karachi.

Almas A, Ghouse A, Iftikhar AR, Khursheed M - Int J Chronic Dis (2014)

Bottom Line: Results.Acute renal failure was the most common complication with a prevalence of 11.5% (24).Conclusion.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, Stadium Road, Aga Khan University, P.O. Box 3500, Karachi 74800, Pakistan.

ABSTRACT
Objectives. Hypertension, if uncontrolled, can lead to hypertensive crisis. We aim to determine the prevalence of hypertensive crisis, its management, and outcome in patients presenting to a tertiary care center in Karachi. Methods. This was a cross-sectional study conducted at the Aga Khan University, Karachi, Pakistan. Adult inpatients (>18 yrs) presenting to the ER who were known hypertensive and had uncontrolled hypertension were included. Results. Out of 1336 patients, 28.6% (387) had uncontrolled hypertension. The prevalence of hypertensive crisis among uncontrolled hypertensive was 56.3% (218). Per oral calcium channel blocker; 35.4% (137) and intravenous nitrate; 22.7% (88) were the most commonly administered medication in the ER. The mean (SD) drop in SBP in patients with hypertensive crisis on intravenous treatment was 53.1 (29) mm Hg and on per oral treatment was 43 (27) mm Hg. The maximum mean (SD) drop in blood pressure was seen by intravenous sodium nitroprusside; 80 (51) mm Hg in SBP. Acute renal failure was the most common complication with a prevalence of 11.5% (24). Conclusion. The prevalence of hypertensive crisis is high. Per oral calcium channel blocker and intravenous nitrate are the most commonly administered medications in our setup.

No MeSH data available.


Related in: MedlinePlus

Trend of systolic blood pressure in ER.
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fig1: Trend of systolic blood pressure in ER.

Mentions: Blood Pressure Trends of Patients with Hypertensive Crisis and without Hypertensive Crisis. The mean (SD) systolic blood pressure (SBP) recorded in patients with hypertensive crisis versus no hypertensive crisis in ER was 202 (17.971) and 158 (13.387) (P value ≤ 0.001). The mean (SD) diastolic blood pressure in patients with hypertensive crisis versus no hypertensive crisis in ER was 108 (17.429) mm Hg and 87 (14.984) mm Hg, respectively, (P value ≤ 0.001). The trend of blood pressure recorded in the ER is shown in Figures 1 and 2.


Hypertensive Crisis, Burden, Management, and Outcome at a Tertiary Care Center in Karachi.

Almas A, Ghouse A, Iftikhar AR, Khursheed M - Int J Chronic Dis (2014)

Trend of systolic blood pressure in ER.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4590913&req=5

fig1: Trend of systolic blood pressure in ER.
Mentions: Blood Pressure Trends of Patients with Hypertensive Crisis and without Hypertensive Crisis. The mean (SD) systolic blood pressure (SBP) recorded in patients with hypertensive crisis versus no hypertensive crisis in ER was 202 (17.971) and 158 (13.387) (P value ≤ 0.001). The mean (SD) diastolic blood pressure in patients with hypertensive crisis versus no hypertensive crisis in ER was 108 (17.429) mm Hg and 87 (14.984) mm Hg, respectively, (P value ≤ 0.001). The trend of blood pressure recorded in the ER is shown in Figures 1 and 2.

Bottom Line: Results.Acute renal failure was the most common complication with a prevalence of 11.5% (24).Conclusion.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, Stadium Road, Aga Khan University, P.O. Box 3500, Karachi 74800, Pakistan.

ABSTRACT
Objectives. Hypertension, if uncontrolled, can lead to hypertensive crisis. We aim to determine the prevalence of hypertensive crisis, its management, and outcome in patients presenting to a tertiary care center in Karachi. Methods. This was a cross-sectional study conducted at the Aga Khan University, Karachi, Pakistan. Adult inpatients (>18 yrs) presenting to the ER who were known hypertensive and had uncontrolled hypertension were included. Results. Out of 1336 patients, 28.6% (387) had uncontrolled hypertension. The prevalence of hypertensive crisis among uncontrolled hypertensive was 56.3% (218). Per oral calcium channel blocker; 35.4% (137) and intravenous nitrate; 22.7% (88) were the most commonly administered medication in the ER. The mean (SD) drop in SBP in patients with hypertensive crisis on intravenous treatment was 53.1 (29) mm Hg and on per oral treatment was 43 (27) mm Hg. The maximum mean (SD) drop in blood pressure was seen by intravenous sodium nitroprusside; 80 (51) mm Hg in SBP. Acute renal failure was the most common complication with a prevalence of 11.5% (24). Conclusion. The prevalence of hypertensive crisis is high. Per oral calcium channel blocker and intravenous nitrate are the most commonly administered medications in our setup.

No MeSH data available.


Related in: MedlinePlus