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Escherichia fergusonii Associated with Pneumonia in a Beef Cow.

Rimoldi GM, Moeller RB - J Vet Med (2013)

Bottom Line: E. fergusonii is a member of Enterobacteriaceae, related to Escherichia coli and Salmonella sp.In veterinary medicine, E. fergusonii has been reported in calves and sheep with clinical cases suggestive of salmonellosis; in a horse and a goat with enteritis and septicemia; and in ostriches with fibrinonecrotic typhlitis.To our knowledge, this report represents the first description of E. fergusonii associated with an acute pneumonia in cattle.

View Article: PubMed Central - PubMed

Affiliation: California Animal Health and Food Safety Laboratory System (CAHFS), Davis and Tulare Branches, 620 West Health Sciences Drive, Davis, CA 95616, USA.

ABSTRACT
An adult Angus cow developed hyperthermia, prostration, and respiratory distress, dying 36 hours after the onset of clinical signs. The main finding during postmortem examination was a severe focally extensive pneumonia. Icterus and a chronic mastitis were also noticed. Histologic examination of the lungs detected fibrinonecrotic pneumonia, with large number of oat cells and intralesional Gram-negative bacterial colonies. Samples from lung lesions were collected, and a pure growth of Escherichia fergusonii was obtained. E. fergusonii is a member of Enterobacteriaceae, related to Escherichia coli and Salmonella sp. In veterinary medicine, E. fergusonii has been reported in calves and sheep with clinical cases suggestive of salmonellosis; in a horse and a goat with enteritis and septicemia; and in ostriches with fibrinonecrotic typhlitis. To our knowledge, this report represents the first description of E. fergusonii associated with an acute pneumonia in cattle.

No MeSH data available.


Related in: MedlinePlus

Outermost section of a necrotic area, densely packed neutrophils, and numerous oat cells. Hematoxylin and eosin, 40x, bar = 20 μm. Insert (upper left) displays intralesional, bacterial colonies, Gram-negative coccobacilli. Hucker-Conn Gram stain 100x, bar = 10 μm.
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fig2: Outermost section of a necrotic area, densely packed neutrophils, and numerous oat cells. Hematoxylin and eosin, 40x, bar = 20 μm. Insert (upper left) displays intralesional, bacterial colonies, Gram-negative coccobacilli. Hucker-Conn Gram stain 100x, bar = 10 μm.

Mentions: Sections of lung, liver, spleen, kidney, heart, rumen, abomasum, small, intestine, spiral colon, mammary gland, and brain were fixed in 10% buffered formalin, routinely processed for histology and examined. The primary microscopic lesion was identified in the lungs. It consisted of a fibrinonecrotic bronchopneumonia with large, irregular, necrotic alveolar areas, filled with fibrin and surrounded by densely packed neutrophilic infiltrates, including oat cells, suggestive of Mannheimia spp. or Pasteurella spp. infection (Figure 1). Within the necrotic areas, large numbers of Gram-negative coccobacilli were detected (Figure 2). Lymphatic vessels within interlobular septa were severely distended, filled with fibrin and debris. The liver displayed centrilobular hepatocellular degeneration, with incipient hepatocyte necrosis (suggestive of hypoxic changes), mild histiocytic infiltration in sinusoids, and increased bile in canaliculi. The mammary gland had a chronic-active suppurative mastitis with increased interlobular fibrosis, multifocal acinar necrosis, neutrophilic exudates into the acinar and ductal lumina, and moderate numbers of intralesional Gram-negative coccobacilli. Rare intraerythrocytic parasites consistent with Anaplasma sp. were detected with Wolbach-Giemsa staining in the liver and lungs and in a smear from the fresh blood sample stained with Diff-Quick (in >1% of RBC, estimated).


Escherichia fergusonii Associated with Pneumonia in a Beef Cow.

Rimoldi GM, Moeller RB - J Vet Med (2013)

Outermost section of a necrotic area, densely packed neutrophils, and numerous oat cells. Hematoxylin and eosin, 40x, bar = 20 μm. Insert (upper left) displays intralesional, bacterial colonies, Gram-negative coccobacilli. Hucker-Conn Gram stain 100x, bar = 10 μm.
© Copyright Policy - open-access
Related In: Results  -  Collection

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getmorefigures.php?uid=PMC4590865&req=5

fig2: Outermost section of a necrotic area, densely packed neutrophils, and numerous oat cells. Hematoxylin and eosin, 40x, bar = 20 μm. Insert (upper left) displays intralesional, bacterial colonies, Gram-negative coccobacilli. Hucker-Conn Gram stain 100x, bar = 10 μm.
Mentions: Sections of lung, liver, spleen, kidney, heart, rumen, abomasum, small, intestine, spiral colon, mammary gland, and brain were fixed in 10% buffered formalin, routinely processed for histology and examined. The primary microscopic lesion was identified in the lungs. It consisted of a fibrinonecrotic bronchopneumonia with large, irregular, necrotic alveolar areas, filled with fibrin and surrounded by densely packed neutrophilic infiltrates, including oat cells, suggestive of Mannheimia spp. or Pasteurella spp. infection (Figure 1). Within the necrotic areas, large numbers of Gram-negative coccobacilli were detected (Figure 2). Lymphatic vessels within interlobular septa were severely distended, filled with fibrin and debris. The liver displayed centrilobular hepatocellular degeneration, with incipient hepatocyte necrosis (suggestive of hypoxic changes), mild histiocytic infiltration in sinusoids, and increased bile in canaliculi. The mammary gland had a chronic-active suppurative mastitis with increased interlobular fibrosis, multifocal acinar necrosis, neutrophilic exudates into the acinar and ductal lumina, and moderate numbers of intralesional Gram-negative coccobacilli. Rare intraerythrocytic parasites consistent with Anaplasma sp. were detected with Wolbach-Giemsa staining in the liver and lungs and in a smear from the fresh blood sample stained with Diff-Quick (in >1% of RBC, estimated).

Bottom Line: E. fergusonii is a member of Enterobacteriaceae, related to Escherichia coli and Salmonella sp.In veterinary medicine, E. fergusonii has been reported in calves and sheep with clinical cases suggestive of salmonellosis; in a horse and a goat with enteritis and septicemia; and in ostriches with fibrinonecrotic typhlitis.To our knowledge, this report represents the first description of E. fergusonii associated with an acute pneumonia in cattle.

View Article: PubMed Central - PubMed

Affiliation: California Animal Health and Food Safety Laboratory System (CAHFS), Davis and Tulare Branches, 620 West Health Sciences Drive, Davis, CA 95616, USA.

ABSTRACT
An adult Angus cow developed hyperthermia, prostration, and respiratory distress, dying 36 hours after the onset of clinical signs. The main finding during postmortem examination was a severe focally extensive pneumonia. Icterus and a chronic mastitis were also noticed. Histologic examination of the lungs detected fibrinonecrotic pneumonia, with large number of oat cells and intralesional Gram-negative bacterial colonies. Samples from lung lesions were collected, and a pure growth of Escherichia fergusonii was obtained. E. fergusonii is a member of Enterobacteriaceae, related to Escherichia coli and Salmonella sp. In veterinary medicine, E. fergusonii has been reported in calves and sheep with clinical cases suggestive of salmonellosis; in a horse and a goat with enteritis and septicemia; and in ostriches with fibrinonecrotic typhlitis. To our knowledge, this report represents the first description of E. fergusonii associated with an acute pneumonia in cattle.

No MeSH data available.


Related in: MedlinePlus