Limits...
Correlation between uterine fibroids with various magnetic resonance imaging features and therapeutic effects of high-intensity focused ultrasound ablation.

Cheng H, Wang C, Tian J - Pak J Med Sci (2015 Jul-Aug)

Bottom Line: Having significantly different ablative effects on UFs with different radial line lengths (F=29.94, P<0.05), HIFUA ablated those with radial line lengths of 3-5 cm most effectively.HIFUA exerted significantly different ablative effects on UFs with various MRI features.Therefore, these features were well correlated with the therapeutic effects of HIFUA, allowing MRI as a promising diagnostic protocol.

View Article: PubMed Central - PubMed

Affiliation: Hailing Cheng, Huaihe Hospital of Henan University, Kaifeng 475000, P. R. China.

ABSTRACT

Objective: To explore the correlation between magnetic resonance imaging (MRI) features of uterine fibroids (UFs) and therapeutic effects of high-intensity focused ultrasound ablation (HIFUA), and to provide evidence for UFs diagnosis with MRI in clinical practice.

Methods: Forty-three UFs patients who were treated in our hospital from April 2012 to June 2014 were selected, including 72 UFs (48 multiple and 24 single UFs). Transverse, sagittal and coronal MRI scanning was performed one week before and after HIFUA to record UF number, location, type (intramural fibroid, submucosal fibroid and subserosal fibroid), mean diameter, hemoperfusion state, volume and ablation rate. The patients were followed up in the postoperative 1st, 2nd and 3rd months.

Results: HIFUA exerted the best ablative effect on fibroids on the anterior uterine wall (F=26.763, P=0.036). Various types of fibroids were ablated significantly differently (F=3.406, P<0.05) by HIFUA that was most effective for ablating the subserosal ones. Having significantly different ablative effects on UFs with different radial line lengths (F=29.94, P<0.05), HIFUA ablated those with radial line lengths of 3-5 cm most effectively. For UFs with different T2WI signal intensities, HIFUA also functioned significantly differently (F=3.179, P=0. 03).

Conclusion: HIFUA exerted significantly different ablative effects on UFs with various MRI features. Therefore, these features were well correlated with the therapeutic effects of HIFUA, allowing MRI as a promising diagnostic protocol.

No MeSH data available.


Related in: MedlinePlus

MRI images for UFs with different locations. Left: Before HIFUA; right: after HIFUA.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4590370&req=5

Figure 4: MRI images for UFs with different locations. Left: Before HIFUA; right: after HIFUA.

Mentions: As shown in Fig.3, UFs with different locations are all significantly shrunken by HIFUA (P<0.05). Univariate F test showed these UFs had significantly different ablation rates (F=26.763, P=0.036). Meanwhile, SNK-q test exhibited that HIFUA exerted the best ablative effect on fibroids on the anterior uterine wall, which significantly surpassed those on the lateral, posterior and basal walls (P<0.05). The MRI images before and after HIFUA are shown in Fig.4.


Correlation between uterine fibroids with various magnetic resonance imaging features and therapeutic effects of high-intensity focused ultrasound ablation.

Cheng H, Wang C, Tian J - Pak J Med Sci (2015 Jul-Aug)

MRI images for UFs with different locations. Left: Before HIFUA; right: after HIFUA.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4590370&req=5

Figure 4: MRI images for UFs with different locations. Left: Before HIFUA; right: after HIFUA.
Mentions: As shown in Fig.3, UFs with different locations are all significantly shrunken by HIFUA (P<0.05). Univariate F test showed these UFs had significantly different ablation rates (F=26.763, P=0.036). Meanwhile, SNK-q test exhibited that HIFUA exerted the best ablative effect on fibroids on the anterior uterine wall, which significantly surpassed those on the lateral, posterior and basal walls (P<0.05). The MRI images before and after HIFUA are shown in Fig.4.

Bottom Line: Having significantly different ablative effects on UFs with different radial line lengths (F=29.94, P<0.05), HIFUA ablated those with radial line lengths of 3-5 cm most effectively.HIFUA exerted significantly different ablative effects on UFs with various MRI features.Therefore, these features were well correlated with the therapeutic effects of HIFUA, allowing MRI as a promising diagnostic protocol.

View Article: PubMed Central - PubMed

Affiliation: Hailing Cheng, Huaihe Hospital of Henan University, Kaifeng 475000, P. R. China.

ABSTRACT

Objective: To explore the correlation between magnetic resonance imaging (MRI) features of uterine fibroids (UFs) and therapeutic effects of high-intensity focused ultrasound ablation (HIFUA), and to provide evidence for UFs diagnosis with MRI in clinical practice.

Methods: Forty-three UFs patients who were treated in our hospital from April 2012 to June 2014 were selected, including 72 UFs (48 multiple and 24 single UFs). Transverse, sagittal and coronal MRI scanning was performed one week before and after HIFUA to record UF number, location, type (intramural fibroid, submucosal fibroid and subserosal fibroid), mean diameter, hemoperfusion state, volume and ablation rate. The patients were followed up in the postoperative 1st, 2nd and 3rd months.

Results: HIFUA exerted the best ablative effect on fibroids on the anterior uterine wall (F=26.763, P=0.036). Various types of fibroids were ablated significantly differently (F=3.406, P<0.05) by HIFUA that was most effective for ablating the subserosal ones. Having significantly different ablative effects on UFs with different radial line lengths (F=29.94, P<0.05), HIFUA ablated those with radial line lengths of 3-5 cm most effectively. For UFs with different T2WI signal intensities, HIFUA also functioned significantly differently (F=3.179, P=0. 03).

Conclusion: HIFUA exerted significantly different ablative effects on UFs with various MRI features. Therefore, these features were well correlated with the therapeutic effects of HIFUA, allowing MRI as a promising diagnostic protocol.

No MeSH data available.


Related in: MedlinePlus