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Gastric involvement of sarcoidosis in a patient with multiple lung nodules.

Ceylan E, Şen S, Coşkun A, Meteoğlu İ, Demirtaş N, Çildağ O - J Res Med Sci (2015)

Bottom Line: The gastric involvement is rare and the symptoms may be non-specific.Positron emission tomography/CT showed lung nodules and gastric involvement with mesenteric lymphadenomegalies with pathological uptake of 18F-fluoro-2-deoxy-d-glucose.Pathological examination of the lung biopsy taken by thoracotomy demonstrated non-caseating granulomas.

View Article: PubMed Central - PubMed

Affiliation: Department of Pulmonary Medicine, Adnan Menderes University, Aydin, Turkey.

ABSTRACT
Sarcoidosis is a granulomatous disorder mostly could involve intrathoracic structures. The gastric involvement is rare and the symptoms may be non-specific. We herein report a case of a 56-year-old female patient who was admitted due to chest tightness and discomfort. Computed tomography (CT) of the thorax revealed bilaterally nodular lesions in the lower lobes of the lung and pleural effusion on the left side. Positron emission tomography/CT showed lung nodules and gastric involvement with mesenteric lymphadenomegalies with pathological uptake of 18F-fluoro-2-deoxy-d-glucose. Pathological examination of the lung biopsy taken by thoracotomy demonstrated non-caseating granulomas. The gastric biopsies taken by endoscopy also showed non-caseating granulomas consistent with a diagnosis of sarcoidosis.

No MeSH data available.


Related in: MedlinePlus

Pathology of the gastric antral biopsy (H and E, ×100) showed non-caseating granulomas composed of epithelial and multinucleated giant cells extend under the epithelium from gastric biopsy
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Figure 3: Pathology of the gastric antral biopsy (H and E, ×100) showed non-caseating granulomas composed of epithelial and multinucleated giant cells extend under the epithelium from gastric biopsy

Mentions: Oesophagogastroduodenoscopy was performed due to gastric symptoms and it was revealed a mucosal hyperemia with edema of the gastric antrum and some erosive lesions [Figure 2]. The antral erythematous gastritis and erythematous pangastritis were diagnosed. The specimen was negative for Helicobacter pylori. Mucosal biopsies from the lesions of the gastric antrum showed non-caseating granulomas composed of epithelial and multinucleated giant cells [Figure 3]. Nor microorganism was detected with Periodic Acid-Schiff (PAS) ve Ziehl-Neelsen staining nor foreign or phagocytic particles.


Gastric involvement of sarcoidosis in a patient with multiple lung nodules.

Ceylan E, Şen S, Coşkun A, Meteoğlu İ, Demirtaş N, Çildağ O - J Res Med Sci (2015)

Pathology of the gastric antral biopsy (H and E, ×100) showed non-caseating granulomas composed of epithelial and multinucleated giant cells extend under the epithelium from gastric biopsy
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4590208&req=5

Figure 3: Pathology of the gastric antral biopsy (H and E, ×100) showed non-caseating granulomas composed of epithelial and multinucleated giant cells extend under the epithelium from gastric biopsy
Mentions: Oesophagogastroduodenoscopy was performed due to gastric symptoms and it was revealed a mucosal hyperemia with edema of the gastric antrum and some erosive lesions [Figure 2]. The antral erythematous gastritis and erythematous pangastritis were diagnosed. The specimen was negative for Helicobacter pylori. Mucosal biopsies from the lesions of the gastric antrum showed non-caseating granulomas composed of epithelial and multinucleated giant cells [Figure 3]. Nor microorganism was detected with Periodic Acid-Schiff (PAS) ve Ziehl-Neelsen staining nor foreign or phagocytic particles.

Bottom Line: The gastric involvement is rare and the symptoms may be non-specific.Positron emission tomography/CT showed lung nodules and gastric involvement with mesenteric lymphadenomegalies with pathological uptake of 18F-fluoro-2-deoxy-d-glucose.Pathological examination of the lung biopsy taken by thoracotomy demonstrated non-caseating granulomas.

View Article: PubMed Central - PubMed

Affiliation: Department of Pulmonary Medicine, Adnan Menderes University, Aydin, Turkey.

ABSTRACT
Sarcoidosis is a granulomatous disorder mostly could involve intrathoracic structures. The gastric involvement is rare and the symptoms may be non-specific. We herein report a case of a 56-year-old female patient who was admitted due to chest tightness and discomfort. Computed tomography (CT) of the thorax revealed bilaterally nodular lesions in the lower lobes of the lung and pleural effusion on the left side. Positron emission tomography/CT showed lung nodules and gastric involvement with mesenteric lymphadenomegalies with pathological uptake of 18F-fluoro-2-deoxy-d-glucose. Pathological examination of the lung biopsy taken by thoracotomy demonstrated non-caseating granulomas. The gastric biopsies taken by endoscopy also showed non-caseating granulomas consistent with a diagnosis of sarcoidosis.

No MeSH data available.


Related in: MedlinePlus